Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | CHR17Q12 |
| Enrichment Score (ES) | 0.47925806 |
| Normalized Enrichment Score (NES) | 1.2771527 |
| Nominal p-value | 0.008333334 |
| FDR q-value | 0.46354067 |
| FWER p-Value | 0.921 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 6 | 4.903 | 0.0603 | Yes |
| 2 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 13 | 4.731 | 0.1185 | Yes |
| 3 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 94 | 3.593 | 0.1607 | Yes |
| 4 | SLFN5 | schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286] | 127 | 3.326 | 0.2009 | Yes |
| 5 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 263 | 2.643 | 0.2298 | Yes |
| 6 | SLFN11 | schlafen family member 11 [Source:HGNC Symbol;Acc:HGNC:26633] | 343 | 2.413 | 0.2575 | Yes |
| 7 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 345 | 2.408 | 0.2871 | Yes |
| 8 | RFFL | ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821] | 401 | 2.272 | 0.3137 | Yes |
| 9 | SLFN13 | schlafen family member 13 [Source:HGNC Symbol;Acc:HGNC:26481] | 478 | 2.085 | 0.3374 | Yes |
| 10 | CDK12 | cyclin dependent kinase 12 [Source:HGNC Symbol;Acc:HGNC:24224] | 896 | 1.506 | 0.3446 | Yes |
| 11 | NLE1 | notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:19889] | 1029 | 1.392 | 0.3582 | Yes |
| 12 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 1191 | 1.261 | 0.3694 | Yes |
| 13 | PIGW | phosphatidylinositol glycan anchor biosynthesis class W [Source:HGNC Symbol;Acc:HGNC:23213] | 1210 | 1.249 | 0.3844 | Yes |
| 14 | CWC25 | CWC25 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:25989] | 1258 | 1.220 | 0.3982 | Yes |
| 15 | STARD3 | StAR related lipid transfer domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17579] | 1406 | 1.155 | 0.4084 | Yes |
| 16 | UNC45B | unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:HGNC:14304] | 1436 | 1.140 | 0.4217 | Yes |
| 17 | PEX12 | peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854] | 1626 | 1.050 | 0.4295 | Yes |
| 18 | MYO19 | myosin XIX [Source:HGNC Symbol;Acc:HGNC:26234] | 1864 | 0.938 | 0.4347 | Yes |
| 19 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 1904 | 0.927 | 0.4451 | Yes |
| 20 | MIEN1 | migration and invasion enhancer 1 [Source:HGNC Symbol;Acc:HGNC:28230] | 1931 | 0.919 | 0.4557 | Yes |
| 21 | DHRS11 | dehydrogenase/reductase 11 [Source:HGNC Symbol;Acc:HGNC:28639] | 1999 | 0.891 | 0.4649 | Yes |
| 22 | TCAP | titin-cap [Source:HGNC Symbol;Acc:HGNC:11610] | 2888 | 0.619 | 0.4485 | Yes |
| 23 | AP2B1 | adaptor related protein complex 2 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:563] | 3020 | 0.585 | 0.4522 | Yes |
| 24 | PSMB3 | proteasome 20S subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:9540] | 3050 | 0.579 | 0.4585 | Yes |
| 25 | AATF | apoptosis antagonizing transcription factor [Source:HGNC Symbol;Acc:HGNC:19235] | 3086 | 0.575 | 0.4647 | Yes |
| 26 | E2F3P1 | E2F transcription factor 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:3116] | 3170 | 0.557 | 0.4693 | Yes |
| 27 | EPOP | elongin BC and polycomb repressive complex 2 associated protein [Source:HGNC Symbol;Acc:HGNC:34493] | 3230 | 0.545 | 0.4744 | Yes |
| 28 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 3295 | 0.530 | 0.4793 | Yes |
| 29 | ZNHIT3 | zinc finger HIT-type containing 3 [Source:HGNC Symbol;Acc:HGNC:12309] | 3626 | 0.467 | 0.4761 | No |
| 30 | FBXO47 | F-box protein 47 [Source:HGNC Symbol;Acc:HGNC:31969] | 4151 | 0.368 | 0.4665 | No |
| 31 | YWHAEP7 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:49437] | 4184 | 0.364 | 0.4701 | No |
| 32 | SRCIN1 | SRC kinase signaling inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:29506] | 4227 | 0.356 | 0.4733 | No |
| 33 | ZNF830 | zinc finger protein 830 [Source:HGNC Symbol;Acc:HGNC:28291] | 4254 | 0.351 | 0.4770 | No |
| 34 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4624 | 0.294 | 0.4706 | No |
| 35 | GGNBP2 | gametogenetin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19357] | 5058 | 0.225 | 0.4617 | No |
| 36 | ARHGAP23 | Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293] | 6037 | 0.087 | 0.4363 | No |
| 37 | PGAP3 | post-GPI attachment to proteins phospholipase 3 [Source:HGNC Symbol;Acc:HGNC:23719] | 6050 | 0.086 | 0.4370 | No |
| 38 | RPL19 | ribosomal protein L19 [Source:HGNC Symbol;Acc:HGNC:10312] | 6442 | 0.035 | 0.4269 | No |
| 39 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6710 | 0.000 | 0.4196 | No |
| 40 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6711 | 0.000 | 0.4196 | No |
| 41 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6712 | 0.000 | 0.4196 | No |
| 42 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6732 | 0.000 | 0.4191 | No |
| 43 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6735 | 0.000 | 0.4191 | No |
| 44 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6737 | 0.000 | 0.4190 | No |
| 45 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6741 | 0.000 | 0.4190 | No |
| 46 | TBC1D3 | TBC1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:19031] | 7874 | 0.000 | 0.3883 | No |
| 47 | LYZL6 | lysozyme like 6 [Source:HGNC Symbol;Acc:HGNC:29614] | 8181 | 0.000 | 0.3801 | No |
| 48 | ASIC2 | acid sensing ion channel subunit 2 [Source:HGNC Symbol;Acc:HGNC:99] | 8233 | 0.000 | 0.3787 | No |
| 49 | MIR2909 | microRNA 2909 [Source:HGNC Symbol;Acc:HGNC:38372] | 9392 | 0.000 | 0.3473 | No |
| 50 | RASL10B | RAS like family 10 member B [Source:HGNC Symbol;Acc:HGNC:30295] | 10070 | 0.000 | 0.3290 | No |
| 51 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 10135 | 0.000 | 0.3273 | No |
| 52 | AA06 | uncharacterized LOC100506677 [Source:NCBI gene (formerly Entrezgene);Acc:100506677] | 10433 | 0.000 | 0.3193 | No |
| 53 | PNMT | phenylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:9160] | 10808 | 0.000 | 0.3091 | No |
| 54 | C17orf78 | chromosome 17 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:26831] | 11964 | 0.000 | 0.2779 | No |
| 55 | C17orf98 | chromosome 17 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:34492] | 11986 | 0.000 | 0.2773 | No |
| 56 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 12223 | 0.000 | 0.2709 | No |
| 57 | SNHG30 | small nucleolar RNA host gene 30 [Source:HGNC Symbol;Acc:HGNC:52836] | 12420 | 0.000 | 0.2656 | No |
| 58 | SLFN14 | schlafen family member 14 [Source:HGNC Symbol;Acc:HGNC:32689] | 12478 | 0.000 | 0.2641 | No |
| 59 | RNU6-1192P | RNA, U6 small nuclear 1192, pseudogene [Source:HGNC Symbol;Acc:HGNC:48155] | 13080 | 0.000 | 0.2478 | No |
| 60 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14915 | 0.000 | 0.1982 | No |
| 61 | SLC35G3 | solute carrier family 35 member G3 [Source:HGNC Symbol;Acc:HGNC:26848] | 16032 | 0.000 | 0.1680 | No |
| 62 | RN7SL301P | RNA, 7SL, cytoplasmic 301, pseudogene [Source:HGNC Symbol;Acc:HGNC:46317] | 16106 | 0.000 | 0.1660 | No |
| 63 | SNORA21 | small nucleolar RNA, H/ACA box 21 [Source:HGNC Symbol;Acc:HGNC:32611] | 16180 | 0.000 | 0.1641 | No |
| 64 | C17orf102 | chromosome 17 open reading frame 102 [Source:HGNC Symbol;Acc:HGNC:34412] | 16649 | 0.000 | 0.1514 | No |
| 65 | RNU6-866P | RNA, U6 small nuclear 866, pseudogene [Source:HGNC Symbol;Acc:HGNC:47829] | 17123 | 0.000 | 0.1386 | No |
| 66 | RNA5SP440 | RNA, 5S ribosomal pseudogene 440 [Source:HGNC Symbol;Acc:HGNC:43340] | 17340 | 0.000 | 0.1328 | No |
| 67 | RNA5SP439 | RNA, 5S ribosomal pseudogene 439 [Source:HGNC Symbol;Acc:HGNC:43339] | 17373 | 0.000 | 0.1319 | No |
| 68 | RNA5SP438 | RNA, 5S ribosomal pseudogene 438 [Source:HGNC Symbol;Acc:HGNC:43338] | 17374 | 0.000 | 0.1319 | No |
| 69 | CCL15-CCL14 | CCL15-CCL14 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44436] | 17485 | 0.000 | 0.1289 | No |
| 70 | SNORD7 | small nucleolar RNA, C/D box 7 [Source:HGNC Symbol;Acc:HGNC:32704] | 17521 | 0.000 | 0.1280 | No |
| 71 | HNF1B | HNF1 homeobox B [Source:HGNC Symbol;Acc:HGNC:11630] | 17642 | 0.000 | 0.1247 | No |
| 72 | PPP1R1B | protein phosphatase 1 regulatory inhibitor subunit 1B [Source:HGNC Symbol;Acc:HGNC:9287] | 17681 | 0.000 | 0.1237 | No |
| 73 | LRRC37A9P | leucine rich repeat containing 37 member A9, pseudogene [Source:HGNC Symbol;Acc:HGNC:43813] | 17724 | 0.000 | 0.1226 | No |
| 74 | RNU6-489P | RNA, U6 small nuclear 489, pseudogene [Source:HGNC Symbol;Acc:HGNC:47452] | 18493 | 0.000 | 0.1018 | No |
| 75 | RNU6-233P | RNA, U6 small nuclear 233, pseudogene [Source:HGNC Symbol;Acc:HGNC:47196] | 18890 | 0.000 | 0.0911 | No |
| 76 | NEUROD2 | neuronal differentiation 2 [Source:HGNC Symbol;Acc:HGNC:7763] | 19239 | 0.000 | 0.0816 | No |
| 77 | LINC01989 | long intergenic non-protein coding RNA 1989 [Source:HGNC Symbol;Acc:HGNC:52821] | 20361 | 0.000 | 0.0513 | No |
| 78 | HEATR9 | HEAT repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:26548] | 21582 | 0.000 | 0.0183 | No |
| 79 | LINC02079 | long intergenic non-protein coding RNA 2079 [Source:HGNC Symbol;Acc:HGNC:52927] | 21678 | 0.000 | 0.0157 | No |
| 80 | TBC1D3K | TBC1 domain family member 3K [Source:HGNC Symbol;Acc:HGNC:51245] | 22300 | 0.000 | -0.0011 | No |
| 81 | TBC1D3L | TBC1 domain family member 3L [Source:HGNC Symbol;Acc:HGNC:51246] | 22301 | 0.000 | -0.0011 | No |
| 82 | TBC1D3B | TBC1 domain family member 3B [Source:HGNC Symbol;Acc:HGNC:27011] | 22307 | 0.000 | -0.0012 | No |
| 83 | TBC1D3E | TBC1 domain family member 3E [Source:HGNC Symbol;Acc:HGNC:27071] | 22309 | 0.000 | -0.0012 | No |
| 84 | TBC1D3F | TBC1 domain family member 3F [Source:HGNC Symbol;Acc:HGNC:18257] | 22310 | 0.000 | -0.0012 | No |
| 85 | TBC1D3C | TBC1 domain family member 3C [Source:HGNC Symbol;Acc:HGNC:24889] | 22312 | 0.000 | -0.0013 | No |
| 86 | TBC1D3D | TBC1 domain family member 3D [Source:HGNC Symbol;Acc:HGNC:28944] | 22313 | 0.000 | -0.0013 | No |
| 87 | TBC1D3I | TBC1 domain family member 3I [Source:HGNC Symbol;Acc:HGNC:32709] | 22314 | 0.000 | -0.0013 | No |
| 88 | TBC1D3J | TBC1 domain family member 3J [Source:HGNC Symbol;Acc:HGNC:51247] | 22316 | 0.000 | -0.0013 | No |
| 89 | TBC1D3G | TBC1 domain family member 3G [Source:HGNC Symbol;Acc:HGNC:29860] | 22318 | 0.000 | -0.0013 | No |
| 90 | TBC1D3H | TBC1 domain family member 3H [Source:HGNC Symbol;Acc:HGNC:30708] | 22319 | 0.000 | -0.0013 | No |
| 91 | TMEM132E | transmembrane protein 132E [Source:HGNC Symbol;Acc:HGNC:26991] | 22545 | 0.000 | -0.0074 | No |
| 92 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22930 | 0.000 | -0.0178 | No |
| 93 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22932 | 0.000 | -0.0178 | No |
| 94 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 22940 | 0.000 | -0.0180 | No |
| 95 | LHX1 | LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6593] | 23261 | 0.000 | -0.0267 | No |
| 96 | FNDC8 | fibronectin type III domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25286] | 25881 | 0.000 | -0.0975 | No |
| 97 | RNU6-840P | RNA, U6 small nuclear 840, pseudogene [Source:HGNC Symbol;Acc:HGNC:47803] | 25985 | 0.000 | -0.1003 | No |
| 98 | GAS2L2 | growth arrest specific 2 like 2 [Source:HGNC Symbol;Acc:HGNC:24846] | 26809 | 0.000 | -0.1226 | No |
| 99 | MIR4734 | microRNA 4734 [Source:HGNC Symbol;Acc:HGNC:41572] | 27225 | 0.000 | -0.1338 | No |
| 100 | MIR4726 | microRNA 4726 [Source:HGNC Symbol;Acc:HGNC:41722] | 27243 | 0.000 | -0.1343 | No |
| 101 | MIR4728 | microRNA 4728 [Source:HGNC Symbol;Acc:HGNC:41632] | 27246 | 0.000 | -0.1343 | No |
| 102 | MIR4727 | microRNA 4727 [Source:HGNC Symbol;Acc:HGNC:41709] | 27247 | 0.000 | -0.1343 | No |
| 103 | LRRC37A11P | leucine rich repeat containing 37 member A11, pseudogene [Source:HGNC Symbol;Acc:HGNC:43815] | 27502 | 0.000 | -0.1412 | No |
| 104 | LIG3 | DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600] | 27663 | -0.022 | -0.1453 | No |
| 105 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27677 | -0.024 | -0.1453 | No |
| 106 | TOMM20P2 | TOMM20 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:50519] | 27793 | -0.037 | -0.1480 | No |
| 107 | SOCS7 | suppressor of cytokine signaling 7 [Source:HGNC Symbol;Acc:HGNC:29846] | 29024 | -0.184 | -0.1790 | No |
| 108 | MLLT6 | MLLT6, PHD finger containing [Source:HGNC Symbol;Acc:HGNC:7138] | 29314 | -0.218 | -0.1841 | No |
| 109 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 29944 | -0.300 | -0.1974 | No |
| 110 | RPL23 | ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316] | 29969 | -0.303 | -0.1943 | No |
| 111 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 30045 | -0.311 | -0.1925 | No |
| 112 | C17orf50 | chromosome 17 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:29581] | 30060 | -0.313 | -0.1890 | No |
| 113 | SYNRG | synergin gamma [Source:HGNC Symbol;Acc:HGNC:557] | 30219 | -0.333 | -0.1892 | No |
| 114 | PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:8998] | 30499 | -0.367 | -0.1922 | No |
| 115 | ARL5C | ADP ribosylation factor like GTPase 5C [Source:HGNC Symbol;Acc:HGNC:31111] | 31227 | -0.474 | -0.2061 | No |
| 116 | HMGB1P24 | high mobility group box 1 pseudogene 24 [Source:HGNC Symbol;Acc:HGNC:39115] | 32453 | -0.705 | -0.2305 | No |
| 117 | MRM1 | mitochondrial rRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26202] | 32544 | -0.721 | -0.2240 | No |
| 118 | CISD3 | CDGSH iron sulfur domain 3 [Source:HGNC Symbol;Acc:HGNC:27578] | 33238 | -0.897 | -0.2317 | No |
| 119 | ACACA | acetyl-CoA carboxylase alpha [Source:HGNC Symbol;Acc:HGNC:84] | 33550 | -0.983 | -0.2280 | No |
| 120 | LINC00672 | long intergenic non-protein coding RNA 672 [Source:HGNC Symbol;Acc:HGNC:44353] | 33750 | -1.047 | -0.2205 | No |
| 121 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 34250 | -1.213 | -0.2190 | No |
| 122 | RDM1 | RAD52 motif containing 1 [Source:HGNC Symbol;Acc:HGNC:19950] | 34654 | -1.373 | -0.2130 | No |
| 123 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 35008 | -1.519 | -0.2038 | No |
| 124 | DDX52 | DExD-box helicase 52 [Source:HGNC Symbol;Acc:HGNC:20038] | 35137 | -1.582 | -0.1877 | No |
| 125 | TADA2A | transcriptional adaptor 2A [Source:HGNC Symbol;Acc:HGNC:11531] | 35302 | -1.677 | -0.1715 | No |
| 126 | MMP28 | matrix metallopeptidase 28 [Source:HGNC Symbol;Acc:HGNC:14366] | 35634 | -1.862 | -0.1575 | No |
| 127 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:1401] | 35832 | -1.997 | -0.1382 | No |
| 128 | GPR179 | G protein-coupled receptor 179 [Source:HGNC Symbol;Acc:HGNC:31371] | 35952 | -2.089 | -0.1156 | No |
| 129 | PLXDC1 | plexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20945] | 36123 | -2.246 | -0.0925 | No |
| 130 | PCGF2 | polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929] | 36648 | -2.843 | -0.0716 | No |
| 131 | FBXL20 | F-box and leucine rich repeat protein 20 [Source:HGNC Symbol;Acc:HGNC:24679] | 36827 | -3.270 | -0.0361 | No |
| 132 | STAC2 | SH3 and cysteine rich domain 2 [Source:HGNC Symbol;Acc:HGNC:23990] | 36912 | -3.499 | 0.0048 | No |
