Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GHANDHI_BYSTANDER_IRRADIATION_UP |
| Enrichment Score (ES) | 0.80056137 |
| Normalized Enrichment Score (NES) | 2.0001433 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.990 | 0.0533 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 3 | 4.934 | 0.1060 | Yes |
| 3 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 10 | 4.776 | 0.1569 | Yes |
| 4 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 15 | 4.682 | 0.2068 | Yes |
| 5 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 40 | 4.234 | 0.2514 | Yes |
| 6 | DUSP5 | dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] | 45 | 4.193 | 0.2961 | Yes |
| 7 | CREB5 | cAMP responsive element binding protein 5 [Source:HGNC Symbol;Acc:HGNC:16844] | 46 | 4.192 | 0.3409 | Yes |
| 8 | SLC7A11 | solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059] | 55 | 4.083 | 0.3844 | Yes |
| 9 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 57 | 4.035 | 0.4275 | Yes |
| 10 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 77 | 3.745 | 0.4670 | Yes |
| 11 | OSGIN2 | oxidative stress induced growth inhibitor family member 2 [Source:HGNC Symbol;Acc:HGNC:1355] | 100 | 3.539 | 0.5042 | Yes |
| 12 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 165 | 3.081 | 0.5354 | Yes |
| 13 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 212 | 2.871 | 0.5649 | Yes |
| 14 | SLC39A14 | solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858] | 224 | 2.791 | 0.5944 | Yes |
| 15 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 257 | 2.668 | 0.6220 | Yes |
| 16 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 284 | 2.578 | 0.6489 | Yes |
| 17 | SERPINB2 | serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584] | 512 | 2.028 | 0.6644 | Yes |
| 18 | ZC3H12C | zinc finger CCCH-type containing 12C [Source:HGNC Symbol;Acc:HGNC:29362] | 513 | 2.024 | 0.6861 | Yes |
| 19 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 549 | 1.970 | 0.7062 | Yes |
| 20 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 673 | 1.758 | 0.7216 | Yes |
| 21 | MT1E | metallothionein 1E [Source:HGNC Symbol;Acc:HGNC:7397] | 1002 | 1.412 | 0.7279 | Yes |
| 22 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 1062 | 1.366 | 0.7409 | Yes |
| 23 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 1762 | 0.979 | 0.7325 | Yes |
| 24 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 2001 | 0.890 | 0.7355 | Yes |
| 25 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 2056 | 0.871 | 0.7434 | Yes |
| 26 | PPP4R3B | protein phosphatase 4 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:29267] | 2183 | 0.824 | 0.7488 | Yes |
| 27 | C9orf72 | C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337] | 2312 | 0.779 | 0.7537 | Yes |
| 28 | SLC16A6 | solute carrier family 16 member 6 [Source:HGNC Symbol;Acc:HGNC:10927] | 2409 | 0.753 | 0.7591 | Yes |
| 29 | SLC39A8 | solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862] | 2482 | 0.729 | 0.7650 | Yes |
| 30 | ZSWIM8 | zinc finger SWIM-type containing 8 [Source:HGNC Symbol;Acc:HGNC:23528] | 2507 | 0.720 | 0.7720 | Yes |
| 31 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 2674 | 0.672 | 0.7747 | Yes |
| 32 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 2716 | 0.662 | 0.7807 | Yes |
| 33 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2775 | 0.646 | 0.7860 | Yes |
| 34 | PLEK2 | pleckstrin 2 [Source:HGNC Symbol;Acc:HGNC:19238] | 2817 | 0.636 | 0.7917 | Yes |
| 35 | MT1B | metallothionein 1B [Source:HGNC Symbol;Acc:HGNC:7394] | 2847 | 0.630 | 0.7976 | Yes |
| 36 | TUT7 | terminal uridylyl transferase 7 [Source:HGNC Symbol;Acc:HGNC:25817] | 3059 | 0.578 | 0.7981 | Yes |
| 37 | MT1H | metallothionein 1H [Source:HGNC Symbol;Acc:HGNC:7400] | 3290 | 0.531 | 0.7976 | Yes |
| 38 | IRAK3 | interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020] | 3383 | 0.511 | 0.8006 | Yes |
| 39 | MT1G | metallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399] | 3901 | 0.417 | 0.7910 | No |
| 40 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 4022 | 0.393 | 0.7920 | No |
| 41 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 4411 | 0.326 | 0.7850 | No |
| 42 | DNAJB4 | DnaJ heat shock protein family (Hsp40) member B4 [Source:HGNC Symbol;Acc:HGNC:14886] | 4502 | 0.312 | 0.7859 | No |
| 43 | RGS9 | regulator of G protein signaling 9 [Source:HGNC Symbol;Acc:HGNC:10004] | 5483 | 0.162 | 0.7612 | No |
| 44 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 5492 | 0.160 | 0.7626 | No |
| 45 | NAMPTP1 | nicotinamide phosphoribosyltransferase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:17633] | 5806 | 0.116 | 0.7554 | No |
| 46 | ATP6V1C1 | ATPase H+ transporting V1 subunit C1 [Source:HGNC Symbol;Acc:HGNC:856] | 5899 | 0.107 | 0.7541 | No |
| 47 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 5930 | 0.103 | 0.7544 | No |
| 48 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 6078 | 0.083 | 0.7513 | No |
| 49 | MCTP2 | multiple C2 and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25636] | 8257 | 0.000 | 0.6924 | No |
| 50 | POPDC3 | popeye domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17649] | 8989 | 0.000 | 0.6727 | No |
| 51 | SLC16A6P1 | SLC16A6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:48932] | 10686 | 0.000 | 0.6269 | No |
| 52 | B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:15684] | 10998 | 0.000 | 0.6185 | No |
| 53 | SLC6A15 | solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621] | 12051 | 0.000 | 0.5900 | No |
| 54 | PTGFR | prostaglandin F receptor [Source:HGNC Symbol;Acc:HGNC:9600] | 12067 | 0.000 | 0.5896 | No |
| 55 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 14006 | 0.000 | 0.5373 | No |
| 56 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208] | 14564 | 0.000 | 0.5222 | No |
| 57 | EPB41L4B | erythrocyte membrane protein band 4.1 like 4B [Source:HGNC Symbol;Acc:HGNC:19818] | 15203 | 0.000 | 0.5050 | No |
| 58 | PRR7-AS1 | PRR7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27961] | 17163 | 0.000 | 0.4520 | No |
| 59 | SRSF12 | serine and arginine rich splicing factor 12 [Source:HGNC Symbol;Acc:HGNC:21220] | 17565 | 0.000 | 0.4412 | No |
| 60 | MMP1 | matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] | 19087 | 0.000 | 0.4001 | No |
| 61 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19424 | 0.000 | 0.3910 | No |
| 62 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19433 | 0.000 | 0.3908 | No |
| 63 | IFNE | interferon epsilon [Source:HGNC Symbol;Acc:HGNC:18163] | 20779 | 0.000 | 0.3545 | No |
| 64 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 20866 | 0.000 | 0.3521 | No |
| 65 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 22057 | 0.000 | 0.3200 | No |
| 66 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 22132 | 0.000 | 0.3180 | No |
| 67 | CD69 | CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694] | 23104 | 0.000 | 0.2918 | No |
| 68 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23782 | 0.000 | 0.2735 | No |
| 69 | C2CD4B | C2 calcium dependent domain containing 4B [Source:HGNC Symbol;Acc:HGNC:33628] | 24709 | 0.000 | 0.2484 | No |
| 70 | FGF2 | fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] | 25434 | 0.000 | 0.2289 | No |
| 71 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 27655 | -0.021 | 0.1691 | No |
| 72 | STC1 | stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373] | 28009 | -0.063 | 0.1602 | No |
| 73 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 28166 | -0.080 | 0.1569 | No |
| 74 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 28537 | -0.124 | 0.1482 | No |
| 75 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 29220 | -0.206 | 0.1320 | No |
| 76 | TESC | tescalcin [Source:HGNC Symbol;Acc:HGNC:26065] | 29256 | -0.212 | 0.1333 | No |
| 77 | GADD45G | growth arrest and DNA damage inducible gamma [Source:HGNC Symbol;Acc:HGNC:4097] | 29334 | -0.221 | 0.1336 | No |
| 78 | MCTP1 | multiple C2 and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26183] | 29456 | -0.236 | 0.1328 | No |
| 79 | PHEX | phosphate regulating endopeptidase homolog X-linked [Source:HGNC Symbol;Acc:HGNC:8918] | 30239 | -0.335 | 0.1153 | No |
| 80 | PLA2G4A | phospholipase A2 group IVA [Source:HGNC Symbol;Acc:HGNC:9035] | 32235 | -0.661 | 0.0685 | No |
| 81 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 33196 | -0.885 | 0.0520 | No |
| 82 | RNF128 | ring finger protein 128 [Source:HGNC Symbol;Acc:HGNC:21153] | 35516 | -1.781 | 0.0083 | No |
| 83 | LRRC8B | leucine rich repeat containing 8 VRAC subunit B [Source:HGNC Symbol;Acc:HGNC:30692] | 36795 | -3.196 | 0.0080 | No |
