Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HECKER_IFNB1_TARGETS |
| Enrichment Score (ES) | 0.82635576 |
| Normalized Enrichment Score (NES) | 2.1066663 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 63 | 3.976 | 0.0402 | Yes |
| 2 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 69 | 3.916 | 0.0813 | Yes |
| 3 | STAP1 | signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133] | 107 | 3.481 | 0.1170 | Yes |
| 4 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 121 | 3.365 | 0.1521 | Yes |
| 5 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 143 | 3.206 | 0.1854 | Yes |
| 6 | DDX58 | DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102] | 151 | 3.149 | 0.2184 | Yes |
| 7 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 154 | 3.130 | 0.2513 | Yes |
| 8 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 168 | 3.071 | 0.2833 | Yes |
| 9 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 173 | 3.047 | 0.3153 | Yes |
| 10 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 181 | 3.025 | 0.3470 | Yes |
| 11 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 183 | 3.012 | 0.3787 | Yes |
| 12 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 184 | 3.012 | 0.4104 | Yes |
| 13 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 211 | 2.872 | 0.4400 | Yes |
| 14 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 214 | 2.849 | 0.4700 | Yes |
| 15 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 233 | 2.756 | 0.4985 | Yes |
| 16 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 235 | 2.744 | 0.5274 | Yes |
| 17 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 258 | 2.666 | 0.5549 | Yes |
| 18 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 272 | 2.610 | 0.5821 | Yes |
| 19 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 305 | 2.496 | 0.6075 | Yes |
| 20 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 365 | 2.347 | 0.6307 | Yes |
| 21 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 391 | 2.293 | 0.6541 | Yes |
| 22 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 421 | 2.219 | 0.6767 | Yes |
| 23 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 506 | 2.036 | 0.6959 | Yes |
| 24 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 509 | 2.033 | 0.7173 | Yes |
| 25 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 595 | 1.883 | 0.7349 | Yes |
| 26 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 613 | 1.855 | 0.7539 | Yes |
| 27 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 658 | 1.777 | 0.7715 | Yes |
| 28 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 977 | 1.436 | 0.7780 | Yes |
| 29 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 981 | 1.431 | 0.7930 | Yes |
| 30 | SH3BGRL2 | SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567] | 1122 | 1.313 | 0.8031 | Yes |
| 31 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 1201 | 1.255 | 0.8142 | Yes |
| 32 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 1233 | 1.234 | 0.8264 | Yes |
| 33 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 2056 | 0.871 | 0.8133 | No |
| 34 | MYL9 | myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754] | 2420 | 0.750 | 0.8114 | No |
| 35 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 2626 | 0.683 | 0.8131 | No |
| 36 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 2983 | 0.590 | 0.8097 | No |
| 37 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 4002 | 0.397 | 0.7863 | No |
| 38 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 4132 | 0.371 | 0.7868 | No |
| 39 | SCO2 | synthesis of cytochrome C oxidase 2 [Source:HGNC Symbol;Acc:HGNC:10604] | 4197 | 0.361 | 0.7888 | No |
| 40 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4624 | 0.294 | 0.7804 | No |
| 41 | C1QB | complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242] | 4634 | 0.292 | 0.7833 | No |
| 42 | DTX3L | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | 4645 | 0.290 | 0.7860 | No |
| 43 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 5571 | 0.150 | 0.7626 | No |
| 44 | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368] | 5902 | 0.107 | 0.7548 | No |
| 45 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 6180 | 0.071 | 0.7481 | No |
| 46 | HES4 | hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149] | 7519 | 0.000 | 0.7119 | No |
| 47 | ARG1 | arginase 1 [Source:HGNC Symbol;Acc:HGNC:663] | 7617 | 0.000 | 0.7093 | No |
| 48 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 8044 | 0.000 | 0.6978 | No |
| 49 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9480 | 0.000 | 0.6590 | No |
| 50 | FCER1A | Fc fragment of IgE receptor Ia [Source:HGNC Symbol;Acc:HGNC:3609] | 10155 | 0.000 | 0.6408 | No |
| 51 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 10485 | 0.000 | 0.6319 | No |
| 52 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10770 | 0.000 | 0.6242 | No |
| 53 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12389 | 0.000 | 0.5805 | No |
| 54 | APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] | 12682 | 0.000 | 0.5726 | No |
| 55 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12685 | 0.000 | 0.5725 | No |
| 56 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13263 | 0.000 | 0.5569 | No |
| 57 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 17186 | 0.000 | 0.4509 | No |
| 58 | SERPING1 | serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] | 17806 | 0.000 | 0.4342 | No |
| 59 | SPON2 | spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253] | 18941 | 0.000 | 0.4036 | No |
| 60 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19424 | 0.000 | 0.3905 | No |
| 61 | CHI3L1 | chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932] | 19822 | 0.000 | 0.3798 | No |
| 62 | C1QA | complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241] | 20095 | 0.000 | 0.3725 | No |
| 63 | C1QC | complement C1q C chain [Source:HGNC Symbol;Acc:HGNC:1245] | 20110 | 0.000 | 0.3721 | No |
| 64 | FFAR2 | free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501] | 20659 | 0.000 | 0.3573 | No |
| 65 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 20673 | 0.000 | 0.3569 | No |
| 66 | MMP25 | matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246] | 20854 | 0.000 | 0.3521 | No |
| 67 | CMTM5 | CKLF like MARVEL transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19176] | 22092 | 0.000 | 0.3186 | No |
| 68 | CMTM2 | CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173] | 22105 | 0.000 | 0.3183 | No |
| 69 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 22694 | 0.000 | 0.3024 | No |
| 70 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22930 | 0.000 | 0.2960 | No |
| 71 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 23308 | 0.000 | 0.2859 | No |
| 72 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23719 | 0.000 | 0.2748 | No |
| 73 | KCNJ15 | potassium inwardly rectifying channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261] | 23922 | 0.000 | 0.2693 | No |
| 74 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 23999 | 0.000 | 0.2673 | No |
| 75 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24566 | 0.000 | 0.2520 | No |
| 76 | CABP5 | calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714] | 24820 | 0.000 | 0.2451 | No |
| 77 | ZBP1 | Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] | 25955 | 0.000 | 0.2145 | No |
| 78 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 26072 | 0.000 | 0.2113 | No |
| 79 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 27277 | 0.000 | 0.1788 | No |
| 80 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 27683 | -0.024 | 0.1681 | No |
| 81 | RPS23 | ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:10410] | 28126 | -0.075 | 0.1570 | No |
| 82 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 29170 | -0.202 | 0.1309 | No |
| 83 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 29220 | -0.206 | 0.1317 | No |
| 84 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 29418 | -0.231 | 0.1289 | No |
| 85 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 31061 | -0.449 | 0.0892 | No |
| 86 | TREML1 | triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434] | 31136 | -0.459 | 0.0920 | No |
| 87 | JUP | junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207] | 31339 | -0.492 | 0.0918 | No |
| 88 | ITGA2B | integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] | 31451 | -0.513 | 0.0942 | No |
| 89 | CYP4F3 | cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646] | 32649 | -0.746 | 0.0697 | No |
| 90 | PROS1 | protein S [Source:HGNC Symbol;Acc:HGNC:9456] | 34322 | -1.241 | 0.0376 | No |
| 91 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 34982 | -1.506 | 0.0356 | No |
| 92 | MGAM | maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043] | 35876 | -2.024 | 0.0328 | No |
