Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | KONG_E2F3_TARGETS |
| Enrichment Score (ES) | -0.7800547 |
| Normalized Enrichment Score (NES) | -1.6659439 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0034921216 |
| FWER p-Value | 0.07 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAS5 | growth arrest specific 5 [Source:HGNC Symbol;Acc:HGNC:16355] | 84 | 3.651 | 0.0224 | No |
| 2 | NR1D1 | nuclear receptor subfamily 1 group D member 1 [Source:HGNC Symbol;Acc:HGNC:7962] | 204 | 2.899 | 0.0387 | No |
| 3 | SRSF7 | serine and arginine rich splicing factor 7 [Source:HGNC Symbol;Acc:HGNC:10789] | 1657 | 1.035 | 0.0065 | No |
| 4 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 1692 | 1.014 | 0.0124 | No |
| 5 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 3295 | 0.530 | -0.0273 | No |
| 6 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 4177 | 0.365 | -0.0487 | No |
| 7 | IGF2BP1 | insulin like growth factor 2 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:28866] | 4633 | 0.292 | -0.0590 | No |
| 8 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 5417 | 0.171 | -0.0790 | No |
| 9 | FBXO45 | F-box protein 45 [Source:HGNC Symbol;Acc:HGNC:29148] | 5491 | 0.160 | -0.0799 | No |
| 10 | H4C15 | H4 clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:29607] | 12862 | 0.000 | -0.2791 | No |
| 11 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16786 | 0.000 | -0.3852 | No |
| 12 | PRL | prolactin [Source:HGNC Symbol;Acc:HGNC:9445] | 20083 | 0.000 | -0.4743 | No |
| 13 | PSORS1C2 | psoriasis susceptibility 1 candidate 2 [Source:HGNC Symbol;Acc:HGNC:17199] | 20736 | 0.000 | -0.4919 | No |
| 14 | F13A1 | coagulation factor XIII A chain [Source:HGNC Symbol;Acc:HGNC:3531] | 22827 | 0.000 | -0.5484 | No |
| 15 | GP1BA | glycoprotein Ib platelet subunit alpha [Source:HGNC Symbol;Acc:HGNC:4439] | 23352 | 0.000 | -0.5626 | No |
| 16 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 27673 | -0.024 | -0.6792 | No |
| 17 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 28496 | -0.118 | -0.7006 | No |
| 18 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 29088 | -0.192 | -0.7153 | No |
| 19 | RPRD1B | regulation of nuclear pre-mRNA domain containing 1B [Source:HGNC Symbol;Acc:HGNC:16209] | 29528 | -0.244 | -0.7255 | No |
| 20 | FAM111A | family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725] | 30332 | -0.345 | -0.7449 | No |
| 21 | MAPK8 | mitogen-activated protein kinase 8 [Source:HGNC Symbol;Acc:HGNC:6881] | 30629 | -0.386 | -0.7503 | No |
| 22 | NUP50 | nucleoporin 50 [Source:HGNC Symbol;Acc:HGNC:8065] | 31395 | -0.504 | -0.7676 | No |
| 23 | CENPQ | centromere protein Q [Source:HGNC Symbol;Acc:HGNC:21347] | 31440 | -0.511 | -0.7653 | No |
| 24 | RPL12 | ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10302] | 31521 | -0.526 | -0.7639 | No |
| 25 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 31702 | -0.560 | -0.7650 | No |
| 26 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32050 | -0.618 | -0.7702 | No |
| 27 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 32315 | -0.677 | -0.7728 | No |
| 28 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 32562 | -0.724 | -0.7745 | No |
| 29 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 32767 | -0.774 | -0.7748 | Yes |
| 30 | TAF1D | TATA-box binding protein associated factor, RNA polymerase I subunit D [Source:HGNC Symbol;Acc:HGNC:28759] | 32784 | -0.779 | -0.7700 | Yes |
| 31 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 32873 | -0.802 | -0.7670 | Yes |
| 32 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33018 | -0.836 | -0.7652 | Yes |
| 33 | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase [Source:HGNC Symbol;Acc:HGNC:20794] | 33309 | -0.916 | -0.7669 | Yes |
| 34 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 33402 | -0.941 | -0.7630 | Yes |
| 35 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33435 | -0.948 | -0.7575 | Yes |
| 36 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33703 | -1.035 | -0.7577 | Yes |
| 37 | RBBP8 | RB binding protein 8, endonuclease [Source:HGNC Symbol;Acc:HGNC:9891] | 33843 | -1.077 | -0.7542 | Yes |
| 38 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33875 | -1.087 | -0.7477 | Yes |
| 39 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 33908 | -1.097 | -0.7412 | Yes |
| 40 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33965 | -1.117 | -0.7351 | Yes |
| 41 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33967 | -1.118 | -0.7276 | Yes |
| 42 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 34258 | -1.217 | -0.7272 | Yes |
| 43 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 34276 | -1.225 | -0.7194 | Yes |
| 44 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34678 | -1.382 | -0.7209 | Yes |
| 45 | FIGNL1 | fidgetin like 1 [Source:HGNC Symbol;Acc:HGNC:13286] | 34716 | -1.402 | -0.7125 | Yes |
| 46 | RPL3 | ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332] | 34804 | -1.438 | -0.7051 | Yes |
| 47 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 34866 | -1.461 | -0.6969 | Yes |
| 48 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34948 | -1.490 | -0.6890 | Yes |
| 49 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35100 | -1.565 | -0.6826 | Yes |
| 50 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35135 | -1.581 | -0.6728 | Yes |
| 51 | RBL1 | RB transcriptional corepressor like 1 [Source:HGNC Symbol;Acc:HGNC:9893] | 35256 | -1.647 | -0.6649 | Yes |
| 52 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 35285 | -1.667 | -0.6544 | Yes |
| 53 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35380 | -1.712 | -0.6454 | Yes |
| 54 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 35395 | -1.722 | -0.6342 | Yes |
| 55 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35440 | -1.743 | -0.6236 | Yes |
| 56 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35447 | -1.747 | -0.6120 | Yes |
| 57 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35471 | -1.761 | -0.6007 | Yes |
| 58 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 35481 | -1.764 | -0.5891 | Yes |
| 59 | HLX | H2.0 like homeobox [Source:HGNC Symbol;Acc:HGNC:4978] | 35486 | -1.769 | -0.5772 | Yes |
| 60 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35498 | -1.774 | -0.5655 | Yes |
| 61 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 35578 | -1.826 | -0.5554 | Yes |
| 62 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35602 | -1.838 | -0.5436 | Yes |
| 63 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35608 | -1.839 | -0.5313 | Yes |
| 64 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35653 | -1.875 | -0.5198 | Yes |
| 65 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35691 | -1.899 | -0.5080 | Yes |
| 66 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35704 | -1.908 | -0.4955 | Yes |
| 67 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35709 | -1.910 | -0.4827 | Yes |
| 68 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35806 | -1.978 | -0.4719 | Yes |
| 69 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35808 | -1.979 | -0.4586 | Yes |
| 70 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35905 | -2.049 | -0.4473 | Yes |
| 71 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35949 | -2.088 | -0.4344 | Yes |
| 72 | CBX2 | chromobox 2 [Source:HGNC Symbol;Acc:HGNC:1552] | 35969 | -2.103 | -0.4207 | Yes |
| 73 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35971 | -2.105 | -0.4065 | Yes |
| 74 | PSIP1 | PC4 and SFRS1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9527] | 36040 | -2.168 | -0.3938 | Yes |
| 75 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36077 | -2.201 | -0.3799 | Yes |
| 76 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36078 | -2.201 | -0.3650 | Yes |
| 77 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36145 | -2.264 | -0.3515 | Yes |
| 78 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 36173 | -2.293 | -0.3368 | Yes |
| 79 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36182 | -2.302 | -0.3215 | Yes |
| 80 | NCAPG2 | non-SMC condensin II complex subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904] | 36193 | -2.309 | -0.3061 | Yes |
| 81 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36203 | -2.318 | -0.2907 | Yes |
| 82 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36336 | -2.447 | -0.2778 | Yes |
| 83 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36341 | -2.453 | -0.2613 | Yes |
| 84 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36418 | -2.536 | -0.2463 | Yes |
| 85 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36429 | -2.546 | -0.2294 | Yes |
| 86 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36471 | -2.598 | -0.2129 | Yes |
| 87 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36474 | -2.605 | -0.1954 | Yes |
| 88 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36530 | -2.698 | -0.1787 | Yes |
| 89 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36614 | -2.799 | -0.1620 | Yes |
| 90 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36617 | -2.804 | -0.1432 | Yes |
| 91 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36642 | -2.836 | -0.1247 | Yes |
| 92 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36707 | -2.964 | -0.1064 | Yes |
| 93 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36772 | -3.113 | -0.0871 | Yes |
| 94 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36823 | -3.251 | -0.0665 | Yes |
| 95 | BRCA1 | BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100] | 36824 | -3.259 | -0.0445 | Yes |
| 96 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36906 | -3.471 | -0.0233 | Yes |
| 97 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37048 | -4.181 | 0.0011 | Yes |
