Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | LEE_EARLY_T_LYMPHOCYTE_UP |
| Enrichment Score (ES) | -0.8068919 |
| Normalized Enrichment Score (NES) | -1.7222487 |
| Nominal p-value | 0.0 |
| FDR q-value | 5.516081E-4 |
| FWER p-Value | 0.006 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RAPGEF5 | Rap guanine nucleotide exchange factor 5 [Source:HGNC Symbol;Acc:HGNC:16862] | 536 | 1.990 | -0.0015 | No |
| 2 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 866 | 1.537 | -0.0004 | No |
| 3 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1522 | 1.100 | -0.0109 | No |
| 4 | SLC1A4 | solute carrier family 1 member 4 [Source:HGNC Symbol;Acc:HGNC:10942] | 1753 | 0.983 | -0.0108 | No |
| 5 | CENPW | centromere protein W [Source:HGNC Symbol;Acc:HGNC:21488] | 2046 | 0.874 | -0.0129 | No |
| 6 | AEBP1 | AE binding protein 1 [Source:HGNC Symbol;Acc:HGNC:303] | 2590 | 0.693 | -0.0231 | No |
| 7 | PON1 | paraoxonase 1 [Source:HGNC Symbol;Acc:HGNC:9204] | 2789 | 0.642 | -0.0243 | No |
| 8 | CDC25A | cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725] | 2842 | 0.631 | -0.0216 | No |
| 9 | GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4129] | 3664 | 0.461 | -0.0408 | No |
| 10 | GNA15 | G protein subunit alpha 15 [Source:HGNC Symbol;Acc:HGNC:4383] | 4897 | 0.247 | -0.0725 | No |
| 11 | PALLD | palladin, cytoskeletal associated protein [Source:HGNC Symbol;Acc:HGNC:17068] | 5394 | 0.173 | -0.0847 | No |
| 12 | FAIM | Fas apoptotic inhibitory molecule [Source:HGNC Symbol;Acc:HGNC:18703] | 5497 | 0.159 | -0.0865 | No |
| 13 | GSE1 | Gse1 coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:28979] | 6372 | 0.045 | -0.1098 | No |
| 14 | MIR646HG | MIR646 host gene [Source:HGNC Symbol;Acc:HGNC:27659] | 8341 | 0.000 | -0.1630 | No |
| 15 | HHIP | hedgehog interacting protein [Source:HGNC Symbol;Acc:HGNC:14866] | 8416 | 0.000 | -0.1650 | No |
| 16 | TNFRSF21 | TNF receptor superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:13469] | 9520 | 0.000 | -0.1948 | No |
| 17 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12730 | 0.000 | -0.2816 | No |
| 18 | SCRN1 | secernin 1 [Source:HGNC Symbol;Acc:HGNC:22192] | 14261 | 0.000 | -0.3230 | No |
| 19 | MZB1 | marginal zone B and B1 cell specific protein [Source:HGNC Symbol;Acc:HGNC:30125] | 14856 | 0.000 | -0.3390 | No |
| 20 | ARPP21 | cAMP regulated phosphoprotein 21 [Source:HGNC Symbol;Acc:HGNC:16968] | 20941 | 0.000 | -0.5036 | No |
| 21 | TSHR | thyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:12373] | 22096 | 0.000 | -0.5348 | No |
| 22 | FAM72C | family with sequence similarity 72 member C [Source:HGNC Symbol;Acc:HGNC:30602] | 22377 | 0.000 | -0.5423 | No |
| 23 | CD1E | CD1e molecule [Source:HGNC Symbol;Acc:HGNC:1638] | 22987 | 0.000 | -0.5588 | No |
| 24 | CD1B | CD1b molecule [Source:HGNC Symbol;Acc:HGNC:1635] | 22990 | 0.000 | -0.5588 | No |
| 25 | CD1A | CD1a molecule [Source:HGNC Symbol;Acc:HGNC:1634] | 22991 | 0.000 | -0.5588 | No |
| 26 | CD99 | CD99 molecule (Xg blood group) [Source:HGNC Symbol;Acc:HGNC:7082] | 23127 | 0.000 | -0.5625 | No |
| 27 | CPVL | carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399] | 23787 | 0.000 | -0.5803 | No |
| 28 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 24136 | 0.000 | -0.5897 | No |
| 29 | NLGN4X | neuroligin 4 X-linked [Source:HGNC Symbol;Acc:HGNC:14287] | 25523 | 0.000 | -0.6272 | No |
| 30 | PALM2AKAP2 | PALM2 and AKAP2 fusion [Source:HGNC Symbol;Acc:HGNC:33529] | 27507 | -0.000 | -0.6808 | No |
| 31 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27890 | -0.049 | -0.6908 | No |
| 32 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 28366 | -0.104 | -0.7030 | No |
| 33 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 28496 | -0.118 | -0.7057 | No |
| 34 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 28817 | -0.156 | -0.7133 | No |
| 35 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 28864 | -0.162 | -0.7135 | No |
| 36 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 29208 | -0.205 | -0.7215 | No |
| 37 | LDLRAD4 | low density lipoprotein receptor class A domain containing 4 [Source:HGNC Symbol;Acc:HGNC:1224] | 29391 | -0.227 | -0.7249 | No |
| 38 | CRNDE | colorectal neoplasia differentially expressed [Source:HGNC Symbol;Acc:HGNC:37078] | 30564 | -0.377 | -0.7541 | No |
| 39 | LETM1 | leucine zipper and EF-hand containing transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:6556] | 30920 | -0.428 | -0.7610 | No |
| 40 | DNTT | DNA nucleotidylexotransferase [Source:HGNC Symbol;Acc:HGNC:2983] | 31010 | -0.441 | -0.7605 | No |
| 41 | TMSB15A | thymosin beta 15a [Source:HGNC Symbol;Acc:HGNC:30744] | 31537 | -0.528 | -0.7713 | No |
| 42 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31593 | -0.538 | -0.7693 | No |
| 43 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 31809 | -0.577 | -0.7713 | No |
| 44 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 32434 | -0.702 | -0.7836 | No |
| 45 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33018 | -0.836 | -0.7939 | No |
| 46 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33435 | -0.948 | -0.7990 | No |
| 47 | RCAN1 | regulator of calcineurin 1 [Source:HGNC Symbol;Acc:HGNC:3040] | 33533 | -0.978 | -0.7952 | No |
| 48 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33965 | -1.117 | -0.7996 | Yes |
| 49 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33967 | -1.118 | -0.7923 | Yes |
| 50 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 34387 | -1.263 | -0.7954 | Yes |
| 51 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34760 | -1.422 | -0.7962 | Yes |
| 52 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 34917 | -1.480 | -0.7908 | Yes |
| 53 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35070 | -1.546 | -0.7848 | Yes |
| 54 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35135 | -1.581 | -0.7763 | Yes |
| 55 | RUFY3 | RUN and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30285] | 35147 | -1.586 | -0.7662 | Yes |
| 56 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35150 | -1.587 | -0.7559 | Yes |
| 57 | DIAPH3 | diaphanous related formin 3 [Source:HGNC Symbol;Acc:HGNC:15480] | 35258 | -1.649 | -0.7481 | Yes |
| 58 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 35285 | -1.667 | -0.7379 | Yes |
| 59 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35447 | -1.747 | -0.7309 | Yes |
| 60 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35498 | -1.774 | -0.7207 | Yes |
| 61 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35559 | -1.810 | -0.7105 | Yes |
| 62 | LRR1 | leucine rich repeat protein 1 [Source:HGNC Symbol;Acc:HGNC:19742] | 35582 | -1.827 | -0.6992 | Yes |
| 63 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35583 | -1.827 | -0.6873 | Yes |
| 64 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35608 | -1.839 | -0.6759 | Yes |
| 65 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35704 | -1.908 | -0.6660 | Yes |
| 66 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35709 | -1.910 | -0.6537 | Yes |
| 67 | KNL1 | kinetochore scaffold 1 [Source:HGNC Symbol;Acc:HGNC:24054] | 35794 | -1.970 | -0.6431 | Yes |
| 68 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35808 | -1.979 | -0.6306 | Yes |
| 69 | DSCC1 | DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453] | 35830 | -1.996 | -0.6181 | Yes |
| 70 | MPP1 | membrane palmitoylated protein 1 [Source:HGNC Symbol;Acc:HGNC:7219] | 35846 | -2.006 | -0.6055 | Yes |
| 71 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 35855 | -2.012 | -0.5926 | Yes |
| 72 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35949 | -2.088 | -0.5815 | Yes |
| 73 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35971 | -2.105 | -0.5683 | Yes |
| 74 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36065 | -2.187 | -0.5566 | Yes |
| 75 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36077 | -2.201 | -0.5425 | Yes |
| 76 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36078 | -2.201 | -0.5282 | Yes |
| 77 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36102 | -2.226 | -0.5143 | Yes |
| 78 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 36109 | -2.234 | -0.4999 | Yes |
| 79 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36111 | -2.235 | -0.4853 | Yes |
| 80 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 36115 | -2.237 | -0.4708 | Yes |
| 81 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36145 | -2.264 | -0.4569 | Yes |
| 82 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36147 | -2.266 | -0.4421 | Yes |
| 83 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 36150 | -2.269 | -0.4274 | Yes |
| 84 | UHRF1 | ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556] | 36191 | -2.308 | -0.4134 | Yes |
| 85 | CXXC5 | CXXC finger protein 5 [Source:HGNC Symbol;Acc:HGNC:26943] | 36260 | -2.367 | -0.3998 | Yes |
| 86 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36291 | -2.397 | -0.3850 | Yes |
| 87 | CEP128 | centrosomal protein 128 [Source:HGNC Symbol;Acc:HGNC:20359] | 36306 | -2.416 | -0.3696 | Yes |
| 88 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 36323 | -2.430 | -0.3542 | Yes |
| 89 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36336 | -2.447 | -0.3386 | Yes |
| 90 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36341 | -2.453 | -0.3227 | Yes |
| 91 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 36348 | -2.461 | -0.3068 | Yes |
| 92 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36380 | -2.489 | -0.2915 | Yes |
| 93 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36445 | -2.564 | -0.2765 | Yes |
| 94 | KIF15 | kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273] | 36451 | -2.572 | -0.2598 | Yes |
| 95 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36471 | -2.598 | -0.2434 | Yes |
| 96 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36474 | -2.605 | -0.2265 | Yes |
| 97 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36492 | -2.640 | -0.2097 | Yes |
| 98 | E2F7 | E2F transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:23820] | 36519 | -2.672 | -0.1930 | Yes |
| 99 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 36520 | -2.674 | -0.1756 | Yes |
| 100 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36541 | -2.717 | -0.1584 | Yes |
| 101 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36614 | -2.799 | -0.1421 | Yes |
| 102 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36707 | -2.964 | -0.1253 | Yes |
| 103 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36716 | -2.984 | -0.1061 | Yes |
| 104 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36779 | -3.125 | -0.0874 | Yes |
| 105 | E2F2 | E2F transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3114] | 36797 | -3.199 | -0.0670 | Yes |
| 106 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36896 | -3.444 | -0.0472 | Yes |
| 107 | NEIL3 | nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573] | 36953 | -3.685 | -0.0247 | Yes |
| 108 | TFDP2 | transcription factor Dp-2 [Source:HGNC Symbol;Acc:HGNC:11751] | 37064 | -4.346 | 0.0007 | Yes |
