Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | LINDSTEDT_DENDRITIC_CELL_MATURATION_A |
| Enrichment Score (ES) | 0.7998641 |
| Normalized Enrichment Score (NES) | 1.914647 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0016329492 |
| FWER p-Value | 0.018 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.990 | 0.0642 | Yes |
| 2 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 1 | 4.986 | 0.1283 | Yes |
| 3 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 2 | 4.934 | 0.1917 | Yes |
| 4 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 6 | 4.903 | 0.2546 | Yes |
| 5 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 13 | 4.731 | 0.3153 | Yes |
| 6 | HCAR3 | hydroxycarboxylic acid receptor 3 [Source:HGNC Symbol;Acc:HGNC:16824] | 29 | 4.435 | 0.3719 | Yes |
| 7 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 39 | 4.237 | 0.4261 | Yes |
| 8 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 44 | 4.198 | 0.4800 | Yes |
| 9 | SLC7A11 | solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059] | 55 | 4.083 | 0.5322 | Yes |
| 10 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 212 | 2.871 | 0.5649 | Yes |
| 11 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 222 | 2.805 | 0.6007 | Yes |
| 12 | PLEK | pleckstrin [Source:HGNC Symbol;Acc:HGNC:9070] | 225 | 2.789 | 0.6365 | Yes |
| 13 | MALT1 | MALT1 paracaspase [Source:HGNC Symbol;Acc:HGNC:6819] | 255 | 2.673 | 0.6701 | Yes |
| 14 | CREM | cAMP responsive element modulator [Source:HGNC Symbol;Acc:HGNC:2352] | 276 | 2.600 | 0.7030 | Yes |
| 15 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 305 | 2.496 | 0.7343 | Yes |
| 16 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 616 | 1.846 | 0.7497 | Yes |
| 17 | SLC3A2 | solute carrier family 3 member 2 [Source:HGNC Symbol;Acc:HGNC:11026] | 1015 | 1.400 | 0.7569 | Yes |
| 18 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1022 | 1.395 | 0.7747 | Yes |
| 19 | PSMA3 | proteasome 20S subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:9532] | 1575 | 1.075 | 0.7736 | Yes |
| 20 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 1767 | 0.978 | 0.7810 | Yes |
| 21 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 2056 | 0.871 | 0.7844 | Yes |
| 22 | TFEC | transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754] | 2352 | 0.769 | 0.7864 | Yes |
| 23 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 2626 | 0.683 | 0.7878 | Yes |
| 24 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2775 | 0.646 | 0.7921 | Yes |
| 25 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 2892 | 0.618 | 0.7969 | Yes |
| 26 | RAB5A | RAB5A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9783] | 3058 | 0.578 | 0.7999 | Yes |
| 27 | FKBP5 | FKBP prolyl isomerase 5 [Source:HGNC Symbol;Acc:HGNC:3721] | 3421 | 0.504 | 0.7966 | No |
| 28 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 4002 | 0.397 | 0.7860 | No |
| 29 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 4022 | 0.393 | 0.7905 | No |
| 30 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 4084 | 0.383 | 0.7938 | No |
| 31 | ACVR2A | activin A receptor type 2A [Source:HGNC Symbol;Acc:HGNC:173] | 4245 | 0.353 | 0.7940 | No |
| 32 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 4513 | 0.310 | 0.7908 | No |
| 33 | PTGER4 | prostaglandin E receptor 4 [Source:HGNC Symbol;Acc:HGNC:9596] | 4559 | 0.302 | 0.7935 | No |
| 34 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4624 | 0.294 | 0.7955 | No |
| 35 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 5243 | 0.197 | 0.7814 | No |
| 36 | P2RX4 | purinergic receptor P2X 4 [Source:HGNC Symbol;Acc:HGNC:8535] | 5337 | 0.183 | 0.7812 | No |
| 37 | GPR137B | G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862] | 6472 | 0.030 | 0.7510 | No |
| 38 | STAT4 | signal transducer and activator of transcription 4 [Source:HGNC Symbol;Acc:HGNC:11365] | 7641 | 0.000 | 0.7194 | No |
| 39 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9128 | 0.000 | 0.6793 | No |
| 40 | TNFRSF4 | TNF receptor superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11918] | 10031 | 0.000 | 0.6549 | No |
| 41 | PLAT | plasminogen activator, tissue type [Source:HGNC Symbol;Acc:HGNC:9051] | 10184 | 0.000 | 0.6508 | No |
| 42 | RTN1 | reticulon 1 [Source:HGNC Symbol;Acc:HGNC:10467] | 10752 | 0.000 | 0.6355 | No |
| 43 | NFE2L3 | nuclear factor, erythroid 2 like 3 [Source:HGNC Symbol;Acc:HGNC:7783] | 17610 | 0.000 | 0.4503 | No |
| 44 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18266 | 0.000 | 0.4327 | No |
| 45 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18906 | 0.000 | 0.4154 | No |
| 46 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19424 | 0.000 | 0.4014 | No |
| 47 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19433 | 0.000 | 0.4012 | No |
| 48 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 22057 | 0.000 | 0.3304 | No |
| 49 | PLA2G7 | phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040] | 22126 | 0.000 | 0.3286 | No |
| 50 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22930 | 0.000 | 0.3069 | No |
| 51 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 22940 | 0.000 | 0.3066 | No |
| 52 | CD48 | CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683] | 23049 | 0.000 | 0.3037 | No |
| 53 | CD58 | CD58 molecule [Source:HGNC Symbol;Acc:HGNC:1688] | 23081 | 0.000 | 0.3029 | No |
| 54 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 24555 | 0.000 | 0.2631 | No |
| 55 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27677 | -0.024 | 0.1791 | No |
| 56 | ATP13A3 | ATPase 13A3 [Source:HGNC Symbol;Acc:HGNC:24113] | 28002 | -0.062 | 0.1712 | No |
| 57 | TRIM16 | tripartite motif containing 16 [Source:HGNC Symbol;Acc:HGNC:17241] | 30728 | -0.401 | 0.1027 | No |
| 58 | PLA2G4A | phospholipase A2 group IVA [Source:HGNC Symbol;Acc:HGNC:9035] | 32235 | -0.661 | 0.0706 | No |
| 59 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 33770 | -1.054 | 0.0427 | No |
| 60 | SCARF1 | scavenger receptor class F member 1 [Source:HGNC Symbol;Acc:HGNC:16820] | 34172 | -1.186 | 0.0471 | No |
| 61 | ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3363] | 36353 | -2.463 | 0.0199 | No |
