Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| Enrichment Score (ES) | -0.8061862 |
| Normalized Enrichment Score (NES) | -1.690321 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0016491165 |
| FWER p-Value | 0.028 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1303 | 1.198 | -0.0265 | No |
| 2 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 1878 | 0.934 | -0.0352 | No |
| 3 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2035 | 0.878 | -0.0330 | No |
| 4 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 2691 | 0.668 | -0.0458 | No |
| 5 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 3413 | 0.506 | -0.0616 | No |
| 6 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 3961 | 0.404 | -0.0734 | No |
| 7 | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101] | 5473 | 0.163 | -0.1131 | No |
| 8 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 5700 | 0.132 | -0.1182 | No |
| 9 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 6544 | 0.021 | -0.1408 | No |
| 10 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12730 | 0.000 | -0.3080 | No |
| 11 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16786 | 0.000 | -0.4176 | No |
| 12 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18447 | 0.000 | -0.4625 | No |
| 13 | RAMP1 | receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843] | 20308 | 0.000 | -0.5127 | No |
| 14 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 24136 | 0.000 | -0.6162 | No |
| 15 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 27731 | -0.030 | -0.7131 | No |
| 16 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27890 | -0.049 | -0.7170 | No |
| 17 | CBX1 | chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551] | 28104 | -0.073 | -0.7222 | No |
| 18 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 28934 | -0.170 | -0.7434 | No |
| 19 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 29088 | -0.192 | -0.7461 | No |
| 20 | SLC16A1 | solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922] | 29283 | -0.215 | -0.7498 | No |
| 21 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30286 | -0.341 | -0.7744 | No |
| 22 | UCK2 | uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562] | 30999 | -0.439 | -0.7904 | No |
| 23 | ACTN4 | actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166] | 31562 | -0.533 | -0.8017 | Yes |
| 24 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31593 | -0.538 | -0.7986 | Yes |
| 25 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 31702 | -0.560 | -0.7974 | Yes |
| 26 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 31809 | -0.577 | -0.7961 | Yes |
| 27 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 31873 | -0.586 | -0.7935 | Yes |
| 28 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 32075 | -0.626 | -0.7944 | Yes |
| 29 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 32463 | -0.708 | -0.7997 | Yes |
| 30 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 32562 | -0.724 | -0.7970 | Yes |
| 31 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 32738 | -0.765 | -0.7962 | Yes |
| 32 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 32873 | -0.802 | -0.7939 | Yes |
| 33 | HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941] | 33269 | -0.909 | -0.7980 | Yes |
| 34 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 33574 | -0.990 | -0.7990 | Yes |
| 35 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 33691 | -1.029 | -0.7946 | Yes |
| 36 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33703 | -1.035 | -0.7873 | Yes |
| 37 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 33829 | -1.073 | -0.7829 | Yes |
| 38 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33967 | -1.118 | -0.7784 | Yes |
| 39 | XRCC6 | X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055] | 34157 | -1.183 | -0.7749 | Yes |
| 40 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34299 | -1.231 | -0.7697 | Yes |
| 41 | CKAP5 | cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] | 34442 | -1.288 | -0.7641 | Yes |
| 42 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 34653 | -1.373 | -0.7598 | Yes |
| 43 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34678 | -1.382 | -0.7503 | Yes |
| 44 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 34680 | -1.382 | -0.7403 | Yes |
| 45 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34692 | -1.386 | -0.7305 | Yes |
| 46 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 34745 | -1.413 | -0.7216 | Yes |
| 47 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34948 | -1.490 | -0.7161 | Yes |
| 48 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 35087 | -1.556 | -0.7085 | Yes |
| 49 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 35090 | -1.560 | -0.6972 | Yes |
| 50 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 35288 | -1.669 | -0.6903 | Yes |
| 51 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35380 | -1.712 | -0.6803 | Yes |
| 52 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35447 | -1.747 | -0.6693 | Yes |
| 53 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35498 | -1.774 | -0.6577 | Yes |
| 54 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 35510 | -1.778 | -0.6450 | Yes |
| 55 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35583 | -1.827 | -0.6336 | Yes |
| 56 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35602 | -1.838 | -0.6207 | Yes |
| 57 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35709 | -1.910 | -0.6096 | Yes |
| 58 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35769 | -1.949 | -0.5970 | Yes |
| 59 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35806 | -1.978 | -0.5835 | Yes |
| 60 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35905 | -2.049 | -0.5712 | Yes |
| 61 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35971 | -2.105 | -0.5576 | Yes |
| 62 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36065 | -2.187 | -0.5441 | Yes |
| 63 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36102 | -2.226 | -0.5289 | Yes |
| 64 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 36115 | -2.237 | -0.5129 | Yes |
| 65 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36147 | -2.266 | -0.4971 | Yes |
| 66 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 36173 | -2.293 | -0.4811 | Yes |
| 67 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36174 | -2.293 | -0.4643 | Yes |
| 68 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36182 | -2.302 | -0.4477 | Yes |
| 69 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36203 | -2.318 | -0.4314 | Yes |
| 70 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36291 | -2.397 | -0.4162 | Yes |
| 71 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36336 | -2.447 | -0.3995 | Yes |
| 72 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36377 | -2.484 | -0.3825 | Yes |
| 73 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36380 | -2.489 | -0.3644 | Yes |
| 74 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36418 | -2.536 | -0.3468 | Yes |
| 75 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36445 | -2.564 | -0.3288 | Yes |
| 76 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36468 | -2.596 | -0.3105 | Yes |
| 77 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36471 | -2.598 | -0.2916 | Yes |
| 78 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36474 | -2.605 | -0.2726 | Yes |
| 79 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36492 | -2.640 | -0.2538 | Yes |
| 80 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36530 | -2.698 | -0.2351 | Yes |
| 81 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36592 | -2.770 | -0.2165 | Yes |
| 82 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36614 | -2.799 | -0.1966 | Yes |
| 83 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36628 | -2.819 | -0.1764 | Yes |
| 84 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 36669 | -2.887 | -0.1564 | Yes |
| 85 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36694 | -2.936 | -0.1356 | Yes |
| 86 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36733 | -3.017 | -0.1146 | Yes |
| 87 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36779 | -3.125 | -0.0930 | Yes |
| 88 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36818 | -3.244 | -0.0704 | Yes |
| 89 | PTGR1 | prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429] | 36879 | -3.391 | -0.0472 | Yes |
| 90 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36896 | -3.444 | -0.0225 | Yes |
| 91 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36977 | -3.801 | 0.0031 | Yes |
