Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.91458994 |
| Normalized Enrichment Score (NES) | 2.321175 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 2 | 4.934 | 0.0278 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 3 | 4.934 | 0.0557 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 16 | 4.671 | 0.0817 | Yes |
| 4 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 23 | 4.507 | 0.1070 | Yes |
| 5 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 31 | 4.386 | 0.1316 | Yes |
| 6 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 35 | 4.322 | 0.1559 | Yes |
| 7 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 39 | 4.237 | 0.1797 | Yes |
| 8 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 43 | 4.211 | 0.2034 | Yes |
| 9 | BCL2L1 | BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992] | 53 | 4.101 | 0.2263 | Yes |
| 10 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 69 | 3.916 | 0.2480 | Yes |
| 11 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 82 | 3.684 | 0.2685 | Yes |
| 12 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 89 | 3.621 | 0.2888 | Yes |
| 13 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 90 | 3.616 | 0.3092 | Yes |
| 14 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 94 | 3.593 | 0.3294 | Yes |
| 15 | GK | glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289] | 98 | 3.555 | 0.3494 | Yes |
| 16 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 102 | 3.525 | 0.3692 | Yes |
| 17 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 106 | 3.492 | 0.3888 | Yes |
| 18 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 114 | 3.436 | 0.4080 | Yes |
| 19 | RHOC | ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669] | 123 | 3.362 | 0.4268 | Yes |
| 20 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 125 | 3.331 | 0.4456 | Yes |
| 21 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 126 | 3.326 | 0.4644 | Yes |
| 22 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 138 | 3.244 | 0.4824 | Yes |
| 23 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 165 | 3.081 | 0.4991 | Yes |
| 24 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 189 | 2.991 | 0.5154 | Yes |
| 25 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 218 | 2.817 | 0.5305 | Yes |
| 26 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 222 | 2.805 | 0.5463 | Yes |
| 27 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 230 | 2.775 | 0.5617 | Yes |
| 28 | STK10 | serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388] | 251 | 2.695 | 0.5764 | Yes |
| 29 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 286 | 2.573 | 0.5900 | Yes |
| 30 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 305 | 2.496 | 0.6036 | Yes |
| 31 | SRGN | serglycin [Source:HGNC Symbol;Acc:HGNC:9361] | 313 | 2.469 | 0.6174 | Yes |
| 32 | PNP | purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892] | 316 | 2.465 | 0.6312 | Yes |
| 33 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 325 | 2.450 | 0.6448 | Yes |
| 34 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 345 | 2.408 | 0.6579 | Yes |
| 35 | MYO10 | myosin X [Source:HGNC Symbol;Acc:HGNC:7593] | 383 | 2.305 | 0.6699 | Yes |
| 36 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 390 | 2.296 | 0.6827 | Yes |
| 37 | LCP2 | lymphocyte cytosolic protein 2 [Source:HGNC Symbol;Acc:HGNC:6529] | 416 | 2.242 | 0.6947 | Yes |
| 38 | IFRD1 | interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456] | 418 | 2.239 | 0.7073 | Yes |
| 39 | TGFB1 | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | 425 | 2.208 | 0.7196 | Yes |
| 40 | APBB1IP | amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379] | 448 | 2.146 | 0.7312 | Yes |
| 41 | DEGS1 | delta 4-desaturase, sphingolipid 1 [Source:HGNC Symbol;Acc:HGNC:13709] | 470 | 2.106 | 0.7425 | Yes |
| 42 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 482 | 2.080 | 0.7539 | Yes |
| 43 | IL1RL1 | interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] | 507 | 2.036 | 0.7648 | Yes |
| 44 | CLEC4D | C-type lectin domain family 4 member D [Source:HGNC Symbol;Acc:HGNC:14554] | 526 | 2.007 | 0.7756 | Yes |
| 45 | SLC20A1 | solute carrier family 20 member 1 [Source:HGNC Symbol;Acc:HGNC:10946] | 530 | 2.003 | 0.7868 | Yes |
| 46 | CFLAR | CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876] | 535 | 1.991 | 0.7980 | Yes |
| 47 | HCLS1 | hematopoietic cell-specific Lyn substrate 1 [Source:HGNC Symbol;Acc:HGNC:4844] | 542 | 1.983 | 0.8090 | Yes |
| 48 | CLN3 | CLN3 lysosomal/endosomal transmembrane protein, battenin [Source:HGNC Symbol;Acc:HGNC:2074] | 558 | 1.953 | 0.8196 | Yes |
| 49 | ETF1 | eukaryotic translation termination factor 1 [Source:HGNC Symbol;Acc:HGNC:3477] | 562 | 1.950 | 0.8306 | Yes |
| 50 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 563 | 1.945 | 0.8415 | Yes |
| 51 | ATF3 | activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785] | 582 | 1.916 | 0.8519 | Yes |
| 52 | RNF11 | ring finger protein 11 [Source:HGNC Symbol;Acc:HGNC:10056] | 666 | 1.767 | 0.8596 | Yes |
| 53 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 758 | 1.641 | 0.8664 | Yes |
| 54 | IRGM | immunity related GTPase M [Source:HGNC Symbol;Acc:HGNC:29597] | 899 | 1.504 | 0.8711 | Yes |
| 55 | JUND | JunD proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6206] | 946 | 1.458 | 0.8781 | Yes |
| 56 | EIF1 | eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249] | 1041 | 1.383 | 0.8834 | Yes |
| 57 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 1062 | 1.366 | 0.8906 | Yes |
| 58 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] | 1073 | 1.356 | 0.8979 | Yes |
| 59 | WSB1 | WD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:19221] | 1285 | 1.210 | 0.8991 | Yes |
| 60 | TOP1 | DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986] | 1427 | 1.145 | 0.9017 | Yes |
| 61 | SLC2A1 | solute carrier family 2 member 1 [Source:HGNC Symbol;Acc:HGNC:11005] | 1528 | 1.098 | 0.9052 | Yes |
| 62 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 1593 | 1.067 | 0.9095 | Yes |
| 63 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 2001 | 0.890 | 0.9035 | Yes |
| 64 | MLLT11 | MLLT11 transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997] | 2005 | 0.889 | 0.9085 | Yes |
| 65 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 2044 | 0.875 | 0.9124 | Yes |
| 66 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 2140 | 0.843 | 0.9146 | Yes |
| 67 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2410 | 0.753 | 0.9116 | No |
| 68 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 2691 | 0.668 | 0.9078 | No |
| 69 | MAP2K1 | mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840] | 2814 | 0.637 | 0.9081 | No |
| 70 | FCGR2B | Fc fragment of IgG receptor IIb [Source:HGNC Symbol;Acc:HGNC:3618] | 5921 | 0.104 | 0.8247 | No |
| 71 | RCN1 | reticulocalbin 1 [Source:HGNC Symbol;Acc:HGNC:9934] | 6463 | 0.031 | 0.8103 | No |
| 72 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6741 | 0.000 | 0.8028 | No |
| 73 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9128 | 0.000 | 0.7383 | No |
| 74 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 9564 | 0.000 | 0.7266 | No |
| 75 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11703 | 0.000 | 0.6688 | No |
| 76 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13628 | 0.000 | 0.6168 | No |
| 77 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 26813 | 0.000 | 0.2605 | No |
| 78 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27677 | -0.024 | 0.2374 | No |
| 79 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 29173 | -0.202 | 0.1981 | No |
| 80 | MAPKAPK2 | MAPK activated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:6887] | 29329 | -0.220 | 0.1951 | No |
| 81 | KPNA3 | karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396] | 29426 | -0.232 | 0.1939 | No |
| 82 | PRKCD | protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399] | 30600 | -0.381 | 0.1643 | No |
| 83 | SAP30 | Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532] | 31471 | -0.517 | 0.1437 | No |
| 84 | PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase type 1 beta [Source:HGNC Symbol;Acc:HGNC:8995] | 31571 | -0.535 | 0.1441 | No |
| 85 | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 [Source:HGNC Symbol;Acc:HGNC:1987] | 33223 | -0.893 | 0.1045 | No |
