Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | REACTOME_FCGR_ACTIVATION |
| Enrichment Score (ES) | 0.90392303 |
| Normalized Enrichment Score (NES) | 2.188456 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 125 | 3.331 | 0.1953 | Yes |
| 2 | FGR | FGR proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3697] | 170 | 3.056 | 0.3764 | Yes |
| 3 | LYN | LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735] | 242 | 2.719 | 0.5366 | Yes |
| 4 | FCGR2A | Fc fragment of IgG receptor IIa [Source:HGNC Symbol;Acc:HGNC:3616] | 271 | 2.622 | 0.6922 | Yes |
| 5 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 707 | 1.710 | 0.7825 | Yes |
| 6 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 866 | 1.537 | 0.8699 | Yes |
| 7 | FYN | FYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4037] | 2383 | 0.760 | 0.8742 | Yes |
| 8 | YES1 | YES proto-oncogene 1, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12841] | 2734 | 0.656 | 0.9039 | Yes |
| 9 | FCGR1A | Fc fragment of IgG receptor Ia [Source:HGNC Symbol;Acc:HGNC:3613] | 4110 | 0.376 | 0.8892 | No |
| 10 | IGHV2-70 | immunoglobulin heavy variable 2-70 [Source:HGNC Symbol;Acc:HGNC:5577] | 6822 | 0.000 | 0.8160 | No |
| 11 | IGHV1-69 | immunoglobulin heavy variable 1-69 [Source:HGNC Symbol;Acc:HGNC:5558] | 7580 | 0.000 | 0.7955 | No |
| 12 | IGHV1-46 | immunoglobulin heavy variable 1-46 [Source:HGNC Symbol;Acc:HGNC:5554] | 7610 | 0.000 | 0.7947 | No |
| 13 | IGLV7-43 | immunoglobulin lambda variable 7-43 [Source:HGNC Symbol;Acc:HGNC:5929] | 8240 | 0.000 | 0.7778 | No |
| 14 | IGKV2-28 | immunoglobulin kappa variable 2-28 [Source:HGNC Symbol;Acc:HGNC:5783] | 8249 | 0.000 | 0.7775 | No |
| 15 | IGKV2-30 | immunoglobulin kappa variable 2-30 [Source:HGNC Symbol;Acc:HGNC:5785] | 8258 | 0.000 | 0.7773 | No |
| 16 | CD247 | CD247 molecule [Source:HGNC Symbol;Acc:HGNC:1677] | 8411 | 0.000 | 0.7732 | No |
| 17 | IGHV3-7 | immunoglobulin heavy variable 3-7 [Source:HGNC Symbol;Acc:HGNC:5620] | 9424 | 0.000 | 0.7459 | No |
| 18 | IGHV4-59 | immunoglobulin heavy variable 4-59 [Source:HGNC Symbol;Acc:HGNC:5654] | 11395 | 0.000 | 0.6927 | No |
| 19 | IGHV4-34 | immunoglobulin heavy variable 4-34 [Source:HGNC Symbol;Acc:HGNC:5650] | 11408 | 0.000 | 0.6923 | No |
| 20 | IGHV4-39 | immunoglobulin heavy variable 4-39 [Source:HGNC Symbol;Acc:HGNC:5651] | 11409 | 0.000 | 0.6923 | No |
| 21 | FCGR3A | Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619] | 11678 | 0.000 | 0.6851 | No |
| 22 | IGLV3-19 | immunoglobulin lambda variable 3-19 [Source:HGNC Symbol;Acc:HGNC:5903] | 11950 | 0.000 | 0.6778 | No |
| 23 | IGLV3-25 | immunoglobulin lambda variable 3-25 [Source:HGNC Symbol;Acc:HGNC:5908] | 11954 | 0.000 | 0.6777 | No |
| 24 | IGLV3-27 | immunoglobulin lambda variable 3-27 [Source:HGNC Symbol;Acc:HGNC:5910] | 11956 | 0.000 | 0.6777 | No |
| 25 | IGLV3-21 | immunoglobulin lambda variable 3-21 [Source:HGNC Symbol;Acc:HGNC:5905] | 11957 | 0.000 | 0.6777 | No |
| 26 | IGLV3-1 | immunoglobulin lambda variable 3-1 [Source:HGNC Symbol;Acc:HGNC:5896] | 12765 | 0.000 | 0.6559 | No |
| 27 | IGKV1-39 | immunoglobulin kappa variable 1-39 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5740] | 12771 | 0.000 | 0.6557 | No |
| 28 | IGKV1-33 | immunoglobulin kappa variable 1-33 [Source:HGNC Symbol;Acc:HGNC:5737] | 12781 | 0.000 | 0.6555 | No |
| 29 | IGKV1-16 | immunoglobulin kappa variable 1-16 [Source:HGNC Symbol;Acc:HGNC:5732] | 12799 | 0.000 | 0.6550 | No |
| 30 | IGKV1-17 | immunoglobulin kappa variable 1-17 [Source:HGNC Symbol;Acc:HGNC:5733] | 12800 | 0.000 | 0.6550 | No |
| 31 | IGKV1-12 | immunoglobulin kappa variable 1-12 [Source:HGNC Symbol;Acc:HGNC:5730] | 12801 | 0.000 | 0.6550 | No |
| 32 | IGKV2D-28 | immunoglobulin kappa variable 2D-28 [Source:HGNC Symbol;Acc:HGNC:5799] | 12924 | 0.000 | 0.6517 | No |
| 33 | IGKV2D-30 | immunoglobulin kappa variable 2D-30 [Source:HGNC Symbol;Acc:HGNC:5801] | 12933 | 0.000 | 0.6515 | No |
| 34 | IGKV2D-40 | immunoglobulin kappa variable 2D-40 [Source:HGNC Symbol;Acc:HGNC:5804] | 12937 | 0.000 | 0.6515 | No |
| 35 | IGKV5-2 | immunoglobulin kappa variable 5-2 [Source:HGNC Symbol;Acc:HGNC:5835] | 14117 | 0.000 | 0.6196 | No |
| 36 | IGLV2-8 | immunoglobulin lambda variable 2-8 [Source:HGNC Symbol;Acc:HGNC:5895] | 15137 | 0.000 | 0.5921 | No |
| 37 | IGLV2-11 | immunoglobulin lambda variable 2-11 [Source:HGNC Symbol;Acc:HGNC:5887] | 16288 | 0.000 | 0.5610 | No |
| 38 | IGLV2-14 | immunoglobulin lambda variable 2-14 [Source:HGNC Symbol;Acc:HGNC:5888] | 16289 | 0.000 | 0.5610 | No |
| 39 | IGLV2-23 | immunoglobulin lambda variable 2-23 [Source:HGNC Symbol;Acc:HGNC:5890] | 16296 | 0.000 | 0.5609 | No |
| 40 | IGHG4 | immunoglobulin heavy constant gamma 4 (G4m marker) [Source:HGNC Symbol;Acc:HGNC:5528] | 17218 | 0.000 | 0.5360 | No |
| 41 | IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) [Source:HGNC Symbol;Acc:HGNC:5525] | 17221 | 0.000 | 0.5359 | No |
| 42 | IGHG2 | immunoglobulin heavy constant gamma 2 (G2m marker) [Source:HGNC Symbol;Acc:HGNC:5526] | 17223 | 0.000 | 0.5359 | No |
| 43 | IGLC3 | immunoglobulin lambda constant 3 (Kern-Oz+ marker) [Source:HGNC Symbol;Acc:HGNC:5857] | 17764 | 0.000 | 0.5213 | No |
| 44 | IGLC2 | immunoglobulin lambda constant 2 [Source:HGNC Symbol;Acc:HGNC:5856] | 17768 | 0.000 | 0.5212 | No |
| 45 | IGHV3-23 | immunoglobulin heavy variable 3-23 [Source:HGNC Symbol;Acc:HGNC:5588] | 18015 | 0.000 | 0.5146 | No |
| 46 | IGHV3-30 | immunoglobulin heavy variable 3-30 [Source:HGNC Symbol;Acc:HGNC:5591] | 18032 | 0.000 | 0.5142 | No |
| 47 | IGHV3-33 | immunoglobulin heavy variable 3-33 [Source:HGNC Symbol;Acc:HGNC:5596] | 18035 | 0.000 | 0.5141 | No |
| 48 | IGHV3-11 | immunoglobulin heavy variable 3-11 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5580] | 18073 | 0.000 | 0.5131 | No |
| 49 | IGHV3-13 | immunoglobulin heavy variable 3-13 [Source:HGNC Symbol;Acc:HGNC:5581] | 18076 | 0.000 | 0.5130 | No |
| 50 | IGHV3-48 | immunoglobulin heavy variable 3-48 [Source:HGNC Symbol;Acc:HGNC:5606] | 18248 | 0.000 | 0.5084 | No |
| 51 | IGHV3-53 | immunoglobulin heavy variable 3-53 [Source:HGNC Symbol;Acc:HGNC:5610] | 18257 | 0.000 | 0.5082 | No |
| 52 | IGKV1-5 | immunoglobulin kappa variable 1-5 [Source:HGNC Symbol;Acc:HGNC:5741] | 18307 | 0.000 | 0.5069 | No |
| 53 | IGKV4-1 | immunoglobulin kappa variable 4-1 [Source:HGNC Symbol;Acc:HGNC:5834] | 19285 | 0.000 | 0.4805 | No |
| 54 | IGKV1D-39 | immunoglobulin kappa variable 1D-39 [Source:HGNC Symbol;Acc:HGNC:5756] | 22850 | 0.000 | 0.3842 | No |
| 55 | IGKV1D-33 | immunoglobulin kappa variable 1D-33 [Source:HGNC Symbol;Acc:HGNC:5753] | 22852 | 0.000 | 0.3842 | No |
| 56 | IGKV1D-16 | immunoglobulin kappa variable 1D-16 [Source:HGNC Symbol;Acc:HGNC:5748] | 22885 | 0.000 | 0.3833 | No |
| 57 | IGKV1D-12 | immunoglobulin kappa variable 1D-12 [Source:HGNC Symbol;Acc:HGNC:5746] | 22892 | 0.000 | 0.3832 | No |
| 58 | CD3G | CD3g molecule [Source:HGNC Symbol;Acc:HGNC:1675] | 23019 | 0.000 | 0.3798 | No |
| 59 | IGLV6-57 | immunoglobulin lambda variable 6-57 [Source:HGNC Symbol;Acc:HGNC:5927] | 23124 | 0.000 | 0.3770 | No |
| 60 | IGKV3D-20 | immunoglobulin kappa variable 3D-20 [Source:HGNC Symbol;Acc:HGNC:5825] | 23899 | 0.000 | 0.3561 | No |
| 61 | IGLV1-40 | immunoglobulin lambda variable 1-40 [Source:HGNC Symbol;Acc:HGNC:5877] | 24612 | 0.000 | 0.3368 | No |
| 62 | IGLV1-47 | immunoglobulin lambda variable 1-47 [Source:HGNC Symbol;Acc:HGNC:5880] | 24613 | 0.000 | 0.3368 | No |
| 63 | IGLV1-44 | immunoglobulin lambda variable 1-44 [Source:HGNC Symbol;Acc:HGNC:5879] | 24614 | 0.000 | 0.3368 | No |
| 64 | IGLV1-51 | immunoglobulin lambda variable 1-51 [Source:HGNC Symbol;Acc:HGNC:5882] | 24628 | 0.000 | 0.3365 | No |
| 65 | IGKV3-15 | immunoglobulin kappa variable 3-15 [Source:HGNC Symbol;Acc:HGNC:5816] | 25140 | 0.000 | 0.3227 | No |
| 66 | IGKV3-11 | immunoglobulin kappa variable 3-11 [Source:HGNC Symbol;Acc:HGNC:5815] | 25145 | 0.000 | 0.3226 | No |
| 67 | IGKV3-20 | immunoglobulin kappa variable 3-20 [Source:HGNC Symbol;Acc:HGNC:5817] | 25171 | 0.000 | 0.3219 | No |
| 68 | IGHV1-2 | immunoglobulin heavy variable 1-2 [Source:HGNC Symbol;Acc:HGNC:5550] | 26910 | 0.000 | 0.2749 | No |
| 69 | IGHV2-5 | immunoglobulin heavy variable 2-5 [Source:HGNC Symbol;Acc:HGNC:5576] | 27318 | 0.000 | 0.2640 | No |
