Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | SEKI_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.8160238 |
| Normalized Enrichment Score (NES) | 2.0000148 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 10 | 4.776 | 0.0384 | Yes |
| 2 | RND1 | Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314] | 19 | 4.543 | 0.0749 | Yes |
| 3 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 28 | 4.437 | 0.1106 | Yes |
| 4 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 37 | 4.309 | 0.1453 | Yes |
| 5 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 48 | 4.167 | 0.1788 | Yes |
| 6 | ZC3H12A | zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259] | 51 | 4.110 | 0.2120 | Yes |
| 7 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 102 | 3.525 | 0.2392 | Yes |
| 8 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 114 | 3.436 | 0.2667 | Yes |
| 9 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 116 | 3.430 | 0.2944 | Yes |
| 10 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 124 | 3.334 | 0.3212 | Yes |
| 11 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 126 | 3.326 | 0.3481 | Yes |
| 12 | SLC4A7 | solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033] | 148 | 3.162 | 0.3732 | Yes |
| 13 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 165 | 3.081 | 0.3977 | Yes |
| 14 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 212 | 2.871 | 0.4197 | Yes |
| 15 | SH3PXD2B | SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242] | 216 | 2.833 | 0.4425 | Yes |
| 16 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 218 | 2.817 | 0.4653 | Yes |
| 17 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 257 | 2.668 | 0.4859 | Yes |
| 18 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 273 | 2.608 | 0.5066 | Yes |
| 19 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 284 | 2.578 | 0.5272 | Yes |
| 20 | ZMYND15 | zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] | 320 | 2.459 | 0.5461 | Yes |
| 21 | SLC11A2 | solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908] | 333 | 2.436 | 0.5655 | Yes |
| 22 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 339 | 2.422 | 0.5850 | Yes |
| 23 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 360 | 2.368 | 0.6036 | Yes |
| 24 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 387 | 2.298 | 0.6215 | Yes |
| 25 | GBP6 | guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395] | 411 | 2.249 | 0.6391 | Yes |
| 26 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 430 | 2.196 | 0.6564 | Yes |
| 27 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 435 | 2.177 | 0.6739 | Yes |
| 28 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 467 | 2.108 | 0.6901 | Yes |
| 29 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 544 | 1.978 | 0.7041 | Yes |
| 30 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 595 | 1.883 | 0.7180 | Yes |
| 31 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 633 | 1.809 | 0.7316 | Yes |
| 32 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 689 | 1.730 | 0.7442 | Yes |
| 33 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 699 | 1.719 | 0.7578 | Yes |
| 34 | EXOC3L4 | exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120] | 773 | 1.618 | 0.7689 | Yes |
| 35 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 847 | 1.549 | 0.7795 | Yes |
| 36 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 900 | 1.503 | 0.7903 | Yes |
| 37 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1022 | 1.395 | 0.7983 | Yes |
| 38 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 1033 | 1.388 | 0.8093 | Yes |
| 39 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 1169 | 1.286 | 0.8160 | Yes |
| 40 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 2056 | 0.871 | 0.7991 | No |
| 41 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 2983 | 0.590 | 0.7789 | No |
| 42 | FAS | Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920] | 3013 | 0.586 | 0.7829 | No |
| 43 | SCHIP1 | schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678] | 3258 | 0.538 | 0.7806 | No |
| 44 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 4411 | 0.326 | 0.7521 | No |
| 45 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 4486 | 0.315 | 0.7527 | No |
| 46 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4624 | 0.294 | 0.7514 | No |
| 47 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 4753 | 0.271 | 0.7501 | No |
| 48 | SELE | selectin E [Source:HGNC Symbol;Acc:HGNC:10718] | 7478 | 0.000 | 0.6765 | No |
| 49 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8892 | 0.000 | 0.6383 | No |
| 50 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 9023 | 0.000 | 0.6348 | No |
| 51 | NGFR | nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809] | 10597 | 0.000 | 0.5923 | No |
| 52 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11434 | 0.000 | 0.5697 | No |
| 53 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11729 | 0.000 | 0.5618 | No |
| 54 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 14058 | 0.000 | 0.4989 | No |
| 55 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 17815 | 0.000 | 0.3974 | No |
| 56 | LRATD1 | LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743] | 18049 | 0.000 | 0.3911 | No |
| 57 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18266 | 0.000 | 0.3853 | No |
| 58 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18985 | 0.000 | 0.3659 | No |
| 59 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19419 | 0.000 | 0.3542 | No |
| 60 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19433 | 0.000 | 0.3538 | No |
| 61 | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223] | 20015 | 0.000 | 0.3381 | No |
| 62 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 22132 | 0.000 | 0.2810 | No |
| 63 | EGFR | epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236] | 22165 | 0.000 | 0.2801 | No |
| 64 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22932 | 0.000 | 0.2594 | No |
| 65 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 26813 | 0.000 | 0.1546 | No |
| 66 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 27655 | -0.021 | 0.1320 | No |
| 67 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27677 | -0.024 | 0.1316 | No |
| 68 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 28166 | -0.080 | 0.1191 | No |
| 69 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 28537 | -0.124 | 0.1101 | No |
| 70 | NEURL3 | neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] | 30127 | -0.321 | 0.0698 | No |
| 71 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 33770 | -1.054 | -0.0201 | No |
| 72 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 33786 | -1.059 | -0.0119 | No |
| 73 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 34600 | -1.356 | -0.0229 | No |
| 74 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 34982 | -1.506 | -0.0210 | No |
| 75 | SLCO4A1 | solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] | 35723 | -1.921 | -0.0254 | No |
| 76 | TJP2 | tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828] | 35885 | -2.032 | -0.0133 | No |
| 77 | RFX5 | regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986] | 36312 | -2.421 | -0.0053 | No |
| 78 | BMP2 | bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069] | 36817 | -3.243 | 0.0074 | No |
