Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | WORSCHECH_TUMOR_REJECTION_UP |
| Enrichment Score (ES) | 0.8203997 |
| Normalized Enrichment Score (NES) | 1.9348311 |
| Nominal p-value | 0.0 |
| FDR q-value | 7.725414E-4 |
| FWER p-Value | 0.008 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.990 | 0.0891 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 6 | 4.903 | 0.1764 | Yes |
| 3 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 10 | 4.776 | 0.2616 | Yes |
| 4 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 16 | 4.671 | 0.3448 | Yes |
| 5 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 40 | 4.234 | 0.4197 | Yes |
| 6 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 57 | 4.035 | 0.4913 | Yes |
| 7 | IL4I1 | interleukin 4 induced 1 [Source:HGNC Symbol;Acc:HGNC:19094] | 83 | 3.660 | 0.5559 | Yes |
| 8 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 189 | 2.991 | 0.6065 | Yes |
| 9 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 263 | 2.643 | 0.6516 | Yes |
| 10 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 391 | 2.293 | 0.6891 | Yes |
| 11 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 446 | 2.147 | 0.7260 | Yes |
| 12 | TLR6 | toll like receptor 6 [Source:HGNC Symbol;Acc:HGNC:16711] | 585 | 1.912 | 0.7564 | Yes |
| 13 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 803 | 1.594 | 0.7790 | Yes |
| 14 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 1180 | 1.276 | 0.7916 | Yes |
| 15 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 1502 | 1.109 | 0.8027 | Yes |
| 16 | NKRF | NFKB repressing factor [Source:HGNC Symbol;Acc:HGNC:19374] | 1562 | 1.081 | 0.8204 | Yes |
| 17 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2775 | 0.646 | 0.7992 | No |
| 18 | CKLF | chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253] | 3386 | 0.510 | 0.7918 | No |
| 19 | IRF6 | interferon regulatory factor 6 [Source:HGNC Symbol;Acc:HGNC:6121] | 3401 | 0.508 | 0.8005 | No |
| 20 | EBF4 | EBF family member 4 [Source:HGNC Symbol;Acc:HGNC:29278] | 3962 | 0.403 | 0.7926 | No |
| 21 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 4383 | 0.331 | 0.7872 | No |
| 22 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 4411 | 0.326 | 0.7923 | No |
| 23 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 4678 | 0.282 | 0.7901 | No |
| 24 | IRF4 | interferon regulatory factor 4 [Source:HGNC Symbol;Acc:HGNC:6119] | 4996 | 0.233 | 0.7857 | No |
| 25 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 5243 | 0.197 | 0.7826 | No |
| 26 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 5333 | 0.183 | 0.7834 | No |
| 27 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6712 | 0.000 | 0.7462 | No |
| 28 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6741 | 0.000 | 0.7455 | No |
| 29 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6742 | 0.000 | 0.7455 | No |
| 30 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 9023 | 0.000 | 0.6839 | No |
| 31 | LY6H | lymphocyte antigen 6 family member H [Source:HGNC Symbol;Acc:HGNC:6728] | 9479 | 0.000 | 0.6716 | No |
| 32 | TNFRSF4 | TNF receptor superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11918] | 10031 | 0.000 | 0.6567 | No |
| 33 | ACKR1 | atypical chemokine receptor 1 (Duffy blood group) [Source:HGNC Symbol;Acc:HGNC:4035] | 11331 | 0.000 | 0.6216 | No |
| 34 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11703 | 0.000 | 0.6116 | No |
| 35 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12389 | 0.000 | 0.5931 | No |
| 36 | TNFSF11 | TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926] | 12645 | 0.000 | 0.5862 | No |
| 37 | TCL1B | T cell leukemia/lymphoma 1B [Source:HGNC Symbol;Acc:HGNC:11649] | 13262 | 0.000 | 0.5696 | No |
| 38 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13628 | 0.000 | 0.5597 | No |
| 39 | IL31 | interleukin 31 [Source:HGNC Symbol;Acc:HGNC:19372] | 14009 | 0.000 | 0.5495 | No |
| 40 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14496 | 0.000 | 0.5364 | No |
| 41 | IL17RB | interleukin 17 receptor B [Source:HGNC Symbol;Acc:HGNC:18015] | 15221 | 0.000 | 0.5168 | No |
| 42 | IL36G | interleukin 36 gamma [Source:HGNC Symbol;Acc:HGNC:15741] | 15777 | 0.000 | 0.5018 | No |
| 43 | CLEC10A | C-type lectin domain containing 10A [Source:HGNC Symbol;Acc:HGNC:16916] | 15867 | 0.000 | 0.4994 | No |
| 44 | IL23R | interleukin 23 receptor [Source:HGNC Symbol;Acc:HGNC:19100] | 15988 | 0.000 | 0.4962 | No |
| 45 | IL5 | interleukin 5 [Source:HGNC Symbol;Acc:HGNC:6016] | 17755 | 0.000 | 0.4485 | No |
| 46 | ITK | IL2 inducible T cell kinase [Source:HGNC Symbol;Acc:HGNC:6171] | 17816 | 0.000 | 0.4469 | No |
| 47 | IFNA13 | interferon alpha 13 [Source:HGNC Symbol;Acc:HGNC:5419] | 18192 | 0.000 | 0.4367 | No |
| 48 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18906 | 0.000 | 0.4175 | No |
| 49 | FASLG | Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936] | 20237 | 0.000 | 0.3816 | No |
| 50 | IFNG | interferon gamma [Source:HGNC Symbol;Acc:HGNC:5438] | 20776 | 0.000 | 0.3670 | No |
| 51 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22930 | 0.000 | 0.3089 | No |
| 52 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 22940 | 0.000 | 0.3086 | No |
| 53 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 23999 | 0.000 | 0.2801 | No |
| 54 | IL17F | interleukin 17F [Source:HGNC Symbol;Acc:HGNC:16404] | 27050 | 0.000 | 0.1977 | No |
| 55 | JCHAIN | joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713] | 27440 | 0.000 | 0.1872 | No |
| 56 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 28206 | -0.085 | 0.1681 | No |
| 57 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 28458 | -0.113 | 0.1633 | No |
| 58 | TAGAP | T cell activation RhoGTPase activating protein [Source:HGNC Symbol;Acc:HGNC:15669] | 30399 | -0.355 | 0.1172 | No |
| 59 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 31061 | -0.449 | 0.1074 | No |
| 60 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 32705 | -0.760 | 0.0766 | No |
| 61 | NKIRAS2 | NFKB inhibitor interacting Ras like 2 [Source:HGNC Symbol;Acc:HGNC:17898] | 34011 | -1.133 | 0.0616 | No |
| 62 | TLR4 | toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850] | 34236 | -1.208 | 0.0771 | No |
