Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GGGNNTTTCC_NFKB_Q6_01 |
| Enrichment Score (ES) | 0.4795423 |
| Normalized Enrichment Score (NES) | 1.2450205 |
| Nominal p-value | 0.02 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 2 | 4.934 | 0.0397 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 6 | 4.903 | 0.0792 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 16 | 4.671 | 0.1166 | Yes |
| 4 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 32 | 4.374 | 0.1515 | Yes |
| 5 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 43 | 4.211 | 0.1852 | Yes |
| 6 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 102 | 3.525 | 0.2120 | Yes |
| 7 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 124 | 3.334 | 0.2383 | Yes |
| 8 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 126 | 3.326 | 0.2651 | Yes |
| 9 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 226 | 2.781 | 0.2849 | Yes |
| 10 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 360 | 2.368 | 0.3004 | Yes |
| 11 | RYBP | RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480] | 370 | 2.328 | 0.3189 | Yes |
| 12 | FHL3 | four and a half LIM domains 3 [Source:HGNC Symbol;Acc:HGNC:3704] | 541 | 1.984 | 0.3303 | Yes |
| 13 | RAP2C | RAP2C, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:21165] | 568 | 1.937 | 0.3452 | Yes |
| 14 | SH2B3 | SH2B adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:29605] | 650 | 1.787 | 0.3574 | Yes |
| 15 | ORAI1 | ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896] | 740 | 1.665 | 0.3685 | Yes |
| 16 | CCDC80 | coiled-coil domain containing 80 [Source:HGNC Symbol;Acc:HGNC:30649] | 753 | 1.649 | 0.3814 | Yes |
| 17 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 790 | 1.606 | 0.3934 | Yes |
| 18 | CPEB4 | cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747] | 821 | 1.574 | 0.4053 | Yes |
| 19 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 947 | 1.457 | 0.4137 | Yes |
| 20 | IER5 | immediate early response 5 [Source:HGNC Symbol;Acc:HGNC:5393] | 1141 | 1.301 | 0.4189 | Yes |
| 21 | ZFAND3 | zinc finger AN1-type containing 3 [Source:HGNC Symbol;Acc:HGNC:18019] | 1223 | 1.242 | 0.4267 | Yes |
| 22 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 1343 | 1.180 | 0.4330 | Yes |
| 23 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 1692 | 1.014 | 0.4318 | Yes |
| 24 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 1705 | 1.006 | 0.4396 | Yes |
| 25 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 1762 | 0.979 | 0.4460 | Yes |
| 26 | TPM3 | tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012] | 1840 | 0.947 | 0.4515 | Yes |
| 27 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 1904 | 0.927 | 0.4573 | Yes |
| 28 | ETV1 | ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490] | 1992 | 0.893 | 0.4621 | Yes |
| 29 | BATF | basic leucine zipper ATF-like transcription factor [Source:HGNC Symbol;Acc:HGNC:958] | 2212 | 0.817 | 0.4628 | Yes |
| 30 | TFEC | transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754] | 2352 | 0.769 | 0.4652 | Yes |
| 31 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2410 | 0.753 | 0.4698 | Yes |
| 32 | GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28804] | 2462 | 0.733 | 0.4743 | Yes |
| 33 | UBE2M | ubiquitin conjugating enzyme E2 M [Source:HGNC Symbol;Acc:HGNC:12491] | 2621 | 0.684 | 0.4755 | Yes |
| 34 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 2674 | 0.672 | 0.4795 | Yes |
| 35 | WNT10A | Wnt family member 10A [Source:HGNC Symbol;Acc:HGNC:13829] | 2991 | 0.589 | 0.4757 | No |
| 36 | RSPRY1 | ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420] | 3151 | 0.562 | 0.4760 | No |
| 37 | RBMS1 | RNA binding motif single stranded interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9907] | 3224 | 0.546 | 0.4784 | No |
| 38 | UPF2 | UPF2 regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:17854] | 3358 | 0.517 | 0.4790 | No |
| 39 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 4084 | 0.383 | 0.4625 | No |
| 40 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 4383 | 0.331 | 0.4571 | No |
| 41 | MAML2 | mastermind like transcriptional coactivator 2 [Source:HGNC Symbol;Acc:HGNC:16259] | 4797 | 0.265 | 0.4480 | No |
| 42 | SLAMF8 | SLAM family member 8 [Source:HGNC Symbol;Acc:HGNC:21391] | 4963 | 0.238 | 0.4455 | No |
| 43 | FUT7 | fucosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4018] | 5598 | 0.146 | 0.4295 | No |
| 44 | SMPD3 | sphingomyelin phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:14240] | 5849 | 0.114 | 0.4237 | No |
| 45 | ENTHD1 | ENTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26352] | 5924 | 0.104 | 0.4225 | No |
| 46 | CDC27 | cell division cycle 27 [Source:HGNC Symbol;Acc:HGNC:1728] | 6158 | 0.072 | 0.4168 | No |
| 47 | KY | kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576] | 6246 | 0.062 | 0.4149 | No |
| 48 | GREM1 | gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001] | 8530 | 0.000 | 0.3531 | No |
| 49 | POU2F3 | POU class 2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:19864] | 8714 | 0.000 | 0.3482 | No |
| 50 | DCLK1 | doublecortin like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2700] | 8956 | 0.000 | 0.3417 | No |
| 51 | PRR34 | PRR34 long non-coding RNA [Source:HGNC Symbol;Acc:HGNC:25606] | 9131 | 0.000 | 0.3370 | No |
| 52 | MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:6765] | 9385 | 0.000 | 0.3301 | No |
| 53 | TNFRSF9 | TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] | 10071 | 0.000 | 0.3116 | No |
| 54 | KCNS3 | potassium voltage-gated channel modifier subfamily S member 3 [Source:HGNC Symbol;Acc:HGNC:6302] | 10179 | 0.000 | 0.3087 | No |
| 55 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10582 | 0.000 | 0.2978 | No |
| 56 | IL1RAPL1 | interleukin 1 receptor accessory protein like 1 [Source:HGNC Symbol;Acc:HGNC:5996] | 10667 | 0.000 | 0.2955 | No |
| 57 | NRIP2 | nuclear receptor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:23078] | 11069 | 0.000 | 0.2847 | No |
| 58 | NTRK3 | neurotrophic receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:8033] | 11189 | 0.000 | 0.2815 | No |
| 59 | CNTF | ciliary neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:2169] | 12555 | 0.000 | 0.2445 | No |
| 60 | SP6 | Sp6 transcription factor [Source:HGNC Symbol;Acc:HGNC:14530] | 12591 | 0.000 | 0.2436 | No |
| 61 | MSX1 | msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391] | 12712 | 0.000 | 0.2403 | No |
| 62 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12993 | 0.000 | 0.2328 | No |
| 63 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13719 | 0.000 | 0.2131 | No |
| 64 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14496 | 0.000 | 0.1921 | No |
| 65 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16347 | 0.000 | 0.1421 | No |
| 66 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 16471 | 0.000 | 0.1388 | No |
| 67 | IL2 | interleukin 2 [Source:HGNC Symbol;Acc:HGNC:6001] | 17752 | 0.000 | 0.1041 | No |
| 68 | LPO | lactoperoxidase [Source:HGNC Symbol;Acc:HGNC:6678] | 18681 | 0.000 | 0.0790 | No |
| 69 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19038 | 0.000 | 0.0694 | No |
| 70 | BNC2 | basonuclin 2 [Source:HGNC Symbol;Acc:HGNC:30988] | 19249 | 0.000 | 0.0637 | No |
| 71 | NR2F2 | nuclear receptor subfamily 2 group F member 2 [Source:HGNC Symbol;Acc:HGNC:7976] | 19537 | 0.000 | 0.0559 | No |
| 72 | ZNF532 | zinc finger protein 532 [Source:HGNC Symbol;Acc:HGNC:30940] | 21850 | 0.000 | -0.0066 | No |
| 73 | CD70 | CD70 molecule [Source:HGNC Symbol;Acc:HGNC:11937] | 23087 | 0.000 | -0.0401 | No |
| 74 | C1QL1 | complement C1q like 1 [Source:HGNC Symbol;Acc:HGNC:24182] | 23289 | 0.000 | -0.0455 | No |
| 75 | FOXS1 | forkhead box S1 [Source:HGNC Symbol;Acc:HGNC:3735] | 23488 | 0.000 | -0.0509 | No |
| 76 | LAMA1 | laminin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481] | 23775 | 0.000 | -0.0586 | No |
| 77 | NRGN | neurogranin [Source:HGNC Symbol;Acc:HGNC:8000] | 24202 | 0.000 | -0.0701 | No |
| 78 | FTHL17 | ferritin heavy chain like 17 [Source:HGNC Symbol;Acc:HGNC:3987] | 24453 | 0.000 | -0.0769 | No |
| 79 | FGF1 | fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665] | 25433 | 0.000 | -0.1034 | No |
| 80 | SOX5 | SRY-box transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:11201] | 26166 | 0.000 | -0.1232 | No |
| 81 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 27655 | -0.021 | -0.1633 | No |
| 82 | WRAP53 | WD repeat containing antisense to TP53 [Source:HGNC Symbol;Acc:HGNC:25522] | 27777 | -0.037 | -0.1663 | No |
| 83 | G3BP1 | G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292] | 27933 | -0.055 | -0.1700 | No |
| 84 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 27938 | -0.056 | -0.1697 | No |
| 85 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 28458 | -0.113 | -0.1828 | No |
| 86 | PPP2R5E | protein phosphatase 2 regulatory subunit B'epsilon [Source:HGNC Symbol;Acc:HGNC:9313] | 28805 | -0.156 | -0.1909 | No |
| 87 | GEM | GTP binding protein overexpressed in skeletal muscle [Source:HGNC Symbol;Acc:HGNC:4234] | 28985 | -0.176 | -0.1943 | No |
| 88 | N4BP1 | NEDD4 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29850] | 29108 | -0.194 | -0.1961 | No |
| 89 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 29173 | -0.202 | -0.1962 | No |
| 90 | SLC25A18 | solute carrier family 25 member 18 [Source:HGNC Symbol;Acc:HGNC:10988] | 29483 | -0.238 | -0.2026 | No |
| 91 | CXCR5 | C-X-C motif chemokine receptor 5 [Source:HGNC Symbol;Acc:HGNC:1060] | 29539 | -0.245 | -0.2021 | No |
| 92 | RASSF2 | Ras association domain family member 2 [Source:HGNC Symbol;Acc:HGNC:9883] | 29625 | -0.257 | -0.2024 | No |
| 93 | BMP2K | BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041] | 29719 | -0.269 | -0.2027 | No |
| 94 | PSME3IP1 | proteasome activator subunit 3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29856] | 29806 | -0.281 | -0.2028 | No |
| 95 | TCEA2 | transcription elongation factor A2 [Source:HGNC Symbol;Acc:HGNC:11614] | 29979 | -0.303 | -0.2050 | No |
| 96 | SH3KBP1 | SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867] | 30115 | -0.319 | -0.2060 | No |
| 97 | ARID1A | AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110] | 30208 | -0.331 | -0.2059 | No |
| 98 | PLXNB1 | plexin B1 [Source:HGNC Symbol;Acc:HGNC:9103] | 30262 | -0.338 | -0.2046 | No |
| 99 | TNKS1BP1 | tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081] | 30747 | -0.403 | -0.2144 | No |
| 100 | ENO3 | enolase 3 [Source:HGNC Symbol;Acc:HGNC:3354] | 31623 | -0.543 | -0.2337 | No |
| 101 | CREB1 | cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345] | 31762 | -0.569 | -0.2329 | No |
| 102 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 31839 | -0.581 | -0.2302 | No |
| 103 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 32389 | -0.693 | -0.2395 | No |
| 104 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 32543 | -0.721 | -0.2378 | No |
| 105 | UBE2H | ubiquitin conjugating enzyme E2 H [Source:HGNC Symbol;Acc:HGNC:12484] | 32580 | -0.730 | -0.2329 | No |
| 106 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 32705 | -0.760 | -0.2302 | No |
| 107 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 33196 | -0.885 | -0.2363 | No |
| 108 | PKN1 | protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405] | 33700 | -1.032 | -0.2416 | No |
| 109 | HOXA4 | homeobox A4 [Source:HGNC Symbol;Acc:HGNC:5105] | 33725 | -1.042 | -0.2338 | No |
| 110 | ALG6 | ALG6 alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23157] | 33834 | -1.075 | -0.2281 | No |
| 111 | CHD6 | chromodomain helicase DNA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19057] | 33851 | -1.080 | -0.2198 | No |
| 112 | MIDEAS | mitotic deacetylase associated SANT domain protein [Source:HGNC Symbol;Acc:HGNC:19853] | 33943 | -1.110 | -0.2133 | No |
| 113 | TRIM47 | tripartite motif containing 47 [Source:HGNC Symbol;Acc:HGNC:19020] | 33960 | -1.115 | -0.2047 | No |
| 114 | CCDC107 | coiled-coil domain containing 107 [Source:HGNC Symbol;Acc:HGNC:28465] | 33995 | -1.127 | -0.1966 | No |
| 115 | STX4 | syntaxin 4 [Source:HGNC Symbol;Acc:HGNC:11439] | 34074 | -1.154 | -0.1894 | No |
| 116 | KAT7 | lysine acetyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:17016] | 34096 | -1.161 | -0.1806 | No |
| 117 | PNKD | PNKD metallo-beta-lactamase domain containing [Source:HGNC Symbol;Acc:HGNC:9153] | 34266 | -1.220 | -0.1753 | No |
| 118 | JAK3 | Janus kinase 3 [Source:HGNC Symbol;Acc:HGNC:6193] | 34267 | -1.221 | -0.1655 | No |
| 119 | SLC6A12 | solute carrier family 6 member 12 [Source:HGNC Symbol;Acc:HGNC:11045] | 34302 | -1.232 | -0.1565 | No |
| 120 | TP53 | tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998] | 34573 | -1.344 | -0.1529 | No |
| 121 | RPS6KA4 | ribosomal protein S6 kinase A4 [Source:HGNC Symbol;Acc:HGNC:10433] | 34628 | -1.366 | -0.1434 | No |
| 122 | CNTNAP1 | contactin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:8011] | 34744 | -1.413 | -0.1351 | No |
| 123 | CYLD | CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584] | 35058 | -1.543 | -0.1311 | No |
| 124 | SLC44A1 | solute carrier family 44 member 1 [Source:HGNC Symbol;Acc:HGNC:18798] | 35085 | -1.555 | -0.1193 | No |
| 125 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 35090 | -1.560 | -0.1068 | No |
| 126 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 35245 | -1.643 | -0.0977 | No |
| 127 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 35739 | -1.928 | -0.0955 | No |
| 128 | TOM1L1 | target of myb1 like 1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11983] | 35836 | -1.999 | -0.0820 | No |
| 129 | CALCOCO1 | calcium binding and coiled-coil domain 1 [Source:HGNC Symbol;Acc:HGNC:29306] | 35895 | -2.041 | -0.0671 | No |
| 130 | HIVEP1 | HIVEP zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4920] | 35979 | -2.109 | -0.0524 | No |
| 131 | LIX1L | limb and CNS expressed 1 like [Source:HGNC Symbol;Acc:HGNC:28715] | 36080 | -2.205 | -0.0373 | No |
| 132 | S1PR2 | sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:HGNC:3169] | 36324 | -2.432 | -0.0243 | No |
| 133 | FAM117A | family with sequence similarity 117 member A [Source:HGNC Symbol;Acc:HGNC:24179] | 36365 | -2.473 | -0.0054 | No |
| 134 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36764 | -3.098 | 0.0088 | No |
