Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | MIR4290 |
| Enrichment Score (ES) | 0.574996 |
| Normalized Enrichment Score (NES) | 1.398968 |
| Nominal p-value | 0.010526316 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TRIB1 | tribbles pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:16891] | 38 | 4.281 | 0.0821 | Yes |
| 2 | MAP1B | microtubule associated protein 1B [Source:HGNC Symbol;Acc:HGNC:6836] | 56 | 4.065 | 0.1605 | Yes |
| 3 | CLCF1 | cardiotrophin like cytokine factor 1 [Source:HGNC Symbol;Acc:HGNC:17412] | 68 | 3.919 | 0.2363 | Yes |
| 4 | PTPN5 | protein tyrosine phosphatase non-receptor type 5 [Source:HGNC Symbol;Acc:HGNC:9657] | 119 | 3.422 | 0.3014 | Yes |
| 5 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 160 | 3.106 | 0.3606 | Yes |
| 6 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 244 | 2.715 | 0.4110 | Yes |
| 7 | SESN2 | sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746] | 783 | 1.612 | 0.4278 | Yes |
| 8 | TSPAN5 | tetraspanin 5 [Source:HGNC Symbol;Acc:HGNC:17753] | 883 | 1.521 | 0.4546 | Yes |
| 9 | MAT2A | methionine adenosyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:6904] | 1147 | 1.299 | 0.4728 | Yes |
| 10 | MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1 like [Source:HGNC Symbol;Acc:HGNC:19840] | 1235 | 1.233 | 0.4943 | Yes |
| 11 | ANKRD52 | ankyrin repeat domain 52 [Source:HGNC Symbol;Acc:HGNC:26614] | 1541 | 1.093 | 0.5073 | Yes |
| 12 | MTAP | methylthioadenosine phosphorylase [Source:HGNC Symbol;Acc:HGNC:7413] | 1775 | 0.975 | 0.5199 | Yes |
| 13 | PPP1R9B | protein phosphatase 1 regulatory subunit 9B [Source:HGNC Symbol;Acc:HGNC:9298] | 2316 | 0.778 | 0.5204 | Yes |
| 14 | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:682] | 2361 | 0.766 | 0.5341 | Yes |
| 15 | SMG5 | SMG5 nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:24644] | 2898 | 0.615 | 0.5316 | Yes |
| 16 | NRBP1 | nuclear receptor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7993] | 3156 | 0.560 | 0.5355 | Yes |
| 17 | WIPF2 | WAS/WASL interacting protein family member 2 [Source:HGNC Symbol;Acc:HGNC:30923] | 3321 | 0.524 | 0.5413 | Yes |
| 18 | RPEL1 | ribulose-5-phosphate-3-epimerase like 1 [Source:HGNC Symbol;Acc:HGNC:45241] | 3423 | 0.504 | 0.5483 | Yes |
| 19 | TM2D2 | TM2 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24127] | 3576 | 0.476 | 0.5534 | Yes |
| 20 | CAPZA1 | capping actin protein of muscle Z-line subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:1488] | 3603 | 0.471 | 0.5619 | Yes |
| 21 | SNX8 | sorting nexin 8 [Source:HGNC Symbol;Acc:HGNC:14972] | 4033 | 0.390 | 0.5579 | Yes |
| 22 | ATP8A2 | ATPase phospholipid transporting 8A2 [Source:HGNC Symbol;Acc:HGNC:13533] | 4082 | 0.383 | 0.5640 | Yes |
| 23 | AKIRIN2 | akirin 2 [Source:HGNC Symbol;Acc:HGNC:21407] | 4165 | 0.367 | 0.5689 | Yes |
| 24 | ERLIN2 | ER lipid raft associated 2 [Source:HGNC Symbol;Acc:HGNC:1356] | 4200 | 0.361 | 0.5750 | Yes |
| 25 | CCNT1 | cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599] | 4460 | 0.319 | 0.5742 | No |
| 26 | KDM4A | lysine demethylase 4A [Source:HGNC Symbol;Acc:HGNC:22978] | 5135 | 0.212 | 0.5601 | No |
| 27 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 5212 | 0.201 | 0.5620 | No |
| 28 | ZNF276 | zinc finger protein 276 [Source:HGNC Symbol;Acc:HGNC:23330] | 6527 | 0.024 | 0.5269 | No |
| 29 | STK32C | serine/threonine kinase 32C [Source:HGNC Symbol;Acc:HGNC:21332] | 6560 | 0.021 | 0.5265 | No |
| 30 | NUP188 | nucleoporin 188 [Source:HGNC Symbol;Acc:HGNC:17859] | 6639 | 0.007 | 0.5245 | No |
| 31 | PRPH2 | peripherin 2 [Source:HGNC Symbol;Acc:HGNC:9942] | 8715 | 0.000 | 0.4685 | No |
| 32 | CASP14 | caspase 14 [Source:HGNC Symbol;Acc:HGNC:1502] | 9449 | 0.000 | 0.4487 | No |
| 33 | ZNF185 | zinc finger protein 185 with LIM domain [Source:HGNC Symbol;Acc:HGNC:12976] | 9900 | 0.000 | 0.4365 | No |
| 34 | AWAT1 | acyl-CoA wax alcohol acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23252] | 10099 | 0.000 | 0.4312 | No |
| 35 | ADAM11 | ADAM metallopeptidase domain 11 [Source:HGNC Symbol;Acc:HGNC:189] | 10194 | 0.000 | 0.4286 | No |
| 36 | MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:6882] | 11437 | 0.000 | 0.3951 | No |
| 37 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11757 | 0.000 | 0.3865 | No |
| 38 | LINC02881 | long intergenic non-protein coding RNA 2881 [Source:HGNC Symbol;Acc:HGNC:51236] | 13486 | 0.000 | 0.3398 | No |
| 39 | SORCS2 | sortilin related VPS10 domain containing receptor 2 [Source:HGNC Symbol;Acc:HGNC:16698] | 14850 | 0.000 | 0.3030 | No |
| 40 | RGS17 | regulator of G protein signaling 17 [Source:HGNC Symbol;Acc:HGNC:14088] | 16758 | 0.000 | 0.2515 | No |
| 41 | BDKRB2 | bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030] | 17982 | 0.000 | 0.2184 | No |
| 42 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18907 | 0.000 | 0.1935 | No |
| 43 | KRT77 | keratin 77 [Source:HGNC Symbol;Acc:HGNC:20411] | 22020 | 0.000 | 0.1094 | No |
| 44 | FGF9 | fibroblast growth factor 9 [Source:HGNC Symbol;Acc:HGNC:3687] | 25446 | 0.000 | 0.0169 | No |
| 45 | MS4A6A | membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375] | 26078 | 0.000 | -0.0001 | No |
| 46 | CSN1S1 | casein alpha s1 [Source:HGNC Symbol;Acc:HGNC:2445] | 26395 | 0.000 | -0.0087 | No |
| 47 | ELFN2 | extracellular leucine rich repeat and fibronectin type III domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29396] | 26446 | 0.000 | -0.0100 | No |
| 48 | NFASC | neurofascin [Source:HGNC Symbol;Acc:HGNC:29866] | 27344 | 0.000 | -0.0343 | No |
| 49 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 27582 | -0.010 | -0.0405 | No |
| 50 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 27732 | -0.030 | -0.0439 | No |
| 51 | TIMM23B | translocase of inner mitochondrial membrane 23 homolog B [Source:HGNC Symbol;Acc:HGNC:23581] | 28886 | -0.166 | -0.0718 | No |
| 52 | ZNF541 | zinc finger protein 541 [Source:HGNC Symbol;Acc:HGNC:25294] | 29296 | -0.216 | -0.0787 | No |
| 53 | RPE | ribulose-5-phosphate-3-epimerase [Source:HGNC Symbol;Acc:HGNC:10293] | 29424 | -0.232 | -0.0776 | No |
| 54 | TNKS | tankyrase [Source:HGNC Symbol;Acc:HGNC:11941] | 29973 | -0.303 | -0.0865 | No |
| 55 | TMEM265 | transmembrane protein 265 [Source:HGNC Symbol;Acc:HGNC:51241] | 30438 | -0.359 | -0.0921 | No |
| 56 | ZFAND6 | zinc finger AN1-type containing 6 [Source:HGNC Symbol;Acc:HGNC:30164] | 31741 | -0.566 | -0.1163 | No |
| 57 | TMEM192 | transmembrane protein 192 [Source:HGNC Symbol;Acc:HGNC:26775] | 31887 | -0.588 | -0.1088 | No |
| 58 | ARHGEF17 | Rho guanine nucleotide exchange factor 17 [Source:HGNC Symbol;Acc:HGNC:21726] | 32169 | -0.646 | -0.1038 | No |
| 59 | CCDC9B | coiled-coil domain containing 9B [Source:HGNC Symbol;Acc:HGNC:33488] | 32361 | -0.685 | -0.0957 | No |
| 60 | ENOX2 | ecto-NOX disulfide-thiol exchanger 2 [Source:HGNC Symbol;Acc:HGNC:2259] | 32674 | -0.752 | -0.0895 | No |
| 61 | SART3 | spliceosome associated factor 3, U4/U6 recycling protein [Source:HGNC Symbol;Acc:HGNC:16860] | 33022 | -0.838 | -0.0826 | No |
| 62 | CAMTA1 | calmodulin binding transcription activator 1 [Source:HGNC Symbol;Acc:HGNC:18806] | 33406 | -0.941 | -0.0747 | No |
| 63 | PYCR1 | pyrroline-5-carboxylate reductase 1 [Source:HGNC Symbol;Acc:HGNC:9721] | 33414 | -0.942 | -0.0566 | No |
| 64 | DCTN4 | dynactin subunit 4 [Source:HGNC Symbol;Acc:HGNC:15518] | 33736 | -1.044 | -0.0450 | No |
| 65 | PRKDC | protein kinase, DNA-activated, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9413] | 33969 | -1.119 | -0.0295 | No |
| 66 | GID4 | GID complex subunit 4 homolog [Source:HGNC Symbol;Acc:HGNC:28453] | 34516 | -1.317 | -0.0187 | No |
| 67 | SUN1 | Sad1 and UNC84 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18587] | 35610 | -1.841 | -0.0125 | No |
| 68 | CTDSP2 | CTD small phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:17077] | 36532 | -2.702 | 0.0151 | No |
