Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | SRF_01 |
| Enrichment Score (ES) | 0.6302478 |
| Normalized Enrichment Score (NES) | 1.4460939 |
| Nominal p-value | 0.018181818 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.998 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 37 | 4.309 | 0.0873 | Yes |
| 2 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 109 | 3.467 | 0.1564 | Yes |
| 3 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 210 | 2.872 | 0.2126 | Yes |
| 4 | ACTN1 | actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163] | 295 | 2.526 | 0.2620 | Yes |
| 5 | WDR1 | WD repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12754] | 406 | 2.258 | 0.3053 | Yes |
| 6 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 467 | 2.108 | 0.3469 | Yes |
| 7 | HOXB4 | homeobox B4 [Source:HGNC Symbol;Acc:HGNC:5115] | 508 | 2.034 | 0.3875 | Yes |
| 8 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 563 | 1.945 | 0.4259 | Yes |
| 9 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 641 | 1.798 | 0.4607 | Yes |
| 10 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797] | 705 | 1.713 | 0.4941 | Yes |
| 11 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 790 | 1.606 | 0.5247 | Yes |
| 12 | ACTR3 | actin related protein 3 [Source:HGNC Symbol;Acc:HGNC:170] | 851 | 1.548 | 0.5548 | Yes |
| 13 | CFL1 | cofilin 1 [Source:HGNC Symbol;Acc:HGNC:1874] | 914 | 1.491 | 0.5837 | Yes |
| 14 | MYL6 | myosin light chain 6 [Source:HGNC Symbol;Acc:HGNC:7587] | 1096 | 1.333 | 0.6061 | Yes |
| 15 | MYH11 | myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569] | 1778 | 0.974 | 0.6077 | Yes |
| 16 | CNN2 | calponin 2 [Source:HGNC Symbol;Acc:HGNC:2156] | 2328 | 0.775 | 0.6087 | Yes |
| 17 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 2879 | 0.622 | 0.6066 | Yes |
| 18 | ASB2 | ankyrin repeat and SOCS box containing 2 [Source:HGNC Symbol;Acc:HGNC:16012] | 2974 | 0.593 | 0.6162 | Yes |
| 19 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 2983 | 0.590 | 0.6281 | Yes |
| 20 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 3305 | 0.528 | 0.6302 | Yes |
| 21 | ITGB1BP2 | integrin subunit beta 1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6154] | 4594 | 0.298 | 0.6016 | No |
| 22 | SCOC | short coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:20335] | 5042 | 0.227 | 0.5942 | No |
| 23 | MUS81 | MUS81 structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:29814] | 5376 | 0.176 | 0.5888 | No |
| 24 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 5920 | 0.104 | 0.5762 | No |
| 25 | TNNC1 | troponin C1, slow skeletal and cardiac type [Source:HGNC Symbol;Acc:HGNC:11943] | 6298 | 0.055 | 0.5672 | No |
| 26 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 8410 | 0.000 | 0.5102 | No |
| 27 | NPAS4 | neuronal PAS domain protein 4 [Source:HGNC Symbol;Acc:HGNC:18983] | 10045 | 0.000 | 0.4661 | No |
| 28 | SUSD1 | sushi domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25413] | 10492 | 0.000 | 0.4540 | No |
| 29 | PRM1 | protamine 1 [Source:HGNC Symbol;Acc:HGNC:9447] | 11797 | 0.000 | 0.4188 | No |
| 30 | TNMD | tenomodulin [Source:HGNC Symbol;Acc:HGNC:17757] | 15092 | 0.000 | 0.3299 | No |
| 31 | CA3 | carbonic anhydrase 3 [Source:HGNC Symbol;Acc:HGNC:1374] | 15822 | 0.000 | 0.3102 | No |
| 32 | PHOX2B | paired like homeobox 2B [Source:HGNC Symbol;Acc:HGNC:9143] | 16392 | 0.000 | 0.2949 | No |
| 33 | GPR20 | G protein-coupled receptor 20 [Source:HGNC Symbol;Acc:HGNC:4475] | 17536 | 0.000 | 0.2640 | No |
| 34 | STX10 | syntaxin 10 [Source:HGNC Symbol;Acc:HGNC:11428] | 17711 | 0.000 | 0.2593 | No |
| 35 | IGF2-AS | IGF2 antisense RNA [Source:HGNC Symbol;Acc:HGNC:14062] | 20838 | 0.000 | 0.1749 | No |
| 36 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 22276 | 0.000 | 0.1361 | No |
| 37 | IL17B | interleukin 17B [Source:HGNC Symbol;Acc:HGNC:5982] | 27053 | 0.000 | 0.0072 | No |
| 38 | TPM1 | tropomyosin 1 [Source:HGNC Symbol;Acc:HGNC:12010] | 27525 | -0.002 | -0.0055 | No |
| 39 | CALD1 | caldesmon 1 [Source:HGNC Symbol;Acc:HGNC:1441] | 28054 | -0.067 | -0.0184 | No |
| 40 | IRAG1 | inositol 1,4,5-triphosphate receptor associated 1 [Source:HGNC Symbol;Acc:HGNC:7237] | 28294 | -0.096 | -0.0229 | No |
| 41 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6285] | 28438 | -0.112 | -0.0244 | No |
| 42 | PRUNE2 | prune homolog 2 with BCH domain [Source:HGNC Symbol;Acc:HGNC:25209] | 29838 | -0.285 | -0.0564 | No |
| 43 | TAZ | tafazzin [Source:HGNC Symbol;Acc:HGNC:11577] | 31886 | -0.588 | -0.0996 | No |
| 44 | TGFB1I1 | transforming growth factor beta 1 induced transcript 1 [Source:HGNC Symbol;Acc:HGNC:11767] | 32239 | -0.663 | -0.0955 | No |
| 45 | SETD2 | SET domain containing 2, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:18420] | 33115 | -0.862 | -0.1014 | No |
| 46 | PLCB3 | phospholipase C beta 3 [Source:HGNC Symbol;Acc:HGNC:9056] | 34324 | -1.241 | -0.1086 | No |
| 47 | SLC25A4 | solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990] | 34434 | -1.283 | -0.0853 | No |
| 48 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 34982 | -1.506 | -0.0692 | No |
| 49 | DIXDC1 | DIX domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23695] | 35528 | -1.793 | -0.0472 | No |
| 50 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35854 | -2.011 | -0.0147 | No |
| 51 | VCL | vinculin [Source:HGNC Symbol;Acc:HGNC:12665] | 36235 | -2.347 | 0.0231 | No |
