Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_HMMR |
| Enrichment Score (ES) | -0.8766747 |
| Normalized Enrichment Score (NES) | -1.7147444 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1522 | 1.100 | -0.0287 | No |
| 2 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26185 | 0.000 | -0.6944 | No |
| 3 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27890 | -0.049 | -0.7399 | No |
| 4 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32050 | -0.618 | -0.8452 | No |
| 5 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33018 | -0.836 | -0.8619 | No |
| 6 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33435 | -0.948 | -0.8624 | No |
| 7 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33965 | -1.117 | -0.8641 | Yes |
| 8 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33988 | -1.124 | -0.8520 | Yes |
| 9 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34299 | -1.231 | -0.8465 | Yes |
| 10 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34419 | -1.276 | -0.8353 | Yes |
| 11 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34692 | -1.386 | -0.8270 | Yes |
| 12 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34760 | -1.422 | -0.8128 | Yes |
| 13 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 34850 | -1.453 | -0.7988 | Yes |
| 14 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34948 | -1.490 | -0.7846 | Yes |
| 15 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35100 | -1.565 | -0.7710 | Yes |
| 16 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35283 | -1.667 | -0.7571 | Yes |
| 17 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35385 | -1.715 | -0.7405 | Yes |
| 18 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35447 | -1.747 | -0.7224 | Yes |
| 19 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 35469 | -1.759 | -0.7032 | Yes |
| 20 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35471 | -1.761 | -0.6833 | Yes |
| 21 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35498 | -1.774 | -0.6640 | Yes |
| 22 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35559 | -1.810 | -0.6452 | Yes |
| 23 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35602 | -1.838 | -0.6256 | Yes |
| 24 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35704 | -1.908 | -0.6068 | Yes |
| 25 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35709 | -1.910 | -0.5854 | Yes |
| 26 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35769 | -1.949 | -0.5650 | Yes |
| 27 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35808 | -1.979 | -0.5437 | Yes |
| 28 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35949 | -2.088 | -0.5239 | Yes |
| 29 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35971 | -2.105 | -0.5007 | Yes |
| 30 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36065 | -2.187 | -0.4786 | Yes |
| 31 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36102 | -2.226 | -0.4544 | Yes |
| 32 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36111 | -2.235 | -0.4295 | Yes |
| 33 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36147 | -2.266 | -0.4048 | Yes |
| 34 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36291 | -2.397 | -0.3817 | Yes |
| 35 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36336 | -2.447 | -0.3553 | Yes |
| 36 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36338 | -2.450 | -0.3276 | Yes |
| 37 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36341 | -2.453 | -0.3000 | Yes |
| 38 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36418 | -2.536 | -0.2735 | Yes |
| 39 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36471 | -2.598 | -0.2456 | Yes |
| 40 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36474 | -2.605 | -0.2162 | Yes |
| 41 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36492 | -2.640 | -0.1869 | Yes |
| 42 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36614 | -2.799 | -0.1586 | Yes |
| 43 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36617 | -2.804 | -0.1271 | Yes |
| 44 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36641 | -2.835 | -0.0957 | Yes |
| 45 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36716 | -2.984 | -0.0640 | Yes |
| 46 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36779 | -3.125 | -0.0305 | Yes |
| 47 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36895 | -3.442 | 0.0053 | Yes |
