Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_MCM4 |
| Enrichment Score (ES) | -0.8634569 |
| Normalized Enrichment Score (NES) | -1.703146 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.914854E-4 |
| FWER p-Value | 0.004 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1522 | 1.100 | -0.0302 | No |
| 2 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 1600 | 1.066 | -0.0218 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26185 | 0.000 | -0.6855 | No |
| 4 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 28303 | -0.096 | -0.7417 | No |
| 5 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32050 | -0.618 | -0.8368 | No |
| 6 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 32873 | -0.802 | -0.8510 | No |
| 7 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33018 | -0.836 | -0.8467 | No |
| 8 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33435 | -0.948 | -0.8486 | No |
| 9 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33988 | -1.124 | -0.8524 | Yes |
| 10 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34299 | -1.231 | -0.8486 | Yes |
| 11 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34678 | -1.382 | -0.8451 | Yes |
| 12 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34692 | -1.386 | -0.8318 | Yes |
| 13 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34760 | -1.422 | -0.8195 | Yes |
| 14 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34948 | -1.490 | -0.8099 | Yes |
| 15 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35065 | -1.544 | -0.7978 | Yes |
| 16 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35150 | -1.587 | -0.7843 | Yes |
| 17 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35283 | -1.667 | -0.7714 | Yes |
| 18 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35385 | -1.715 | -0.7572 | Yes |
| 19 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35440 | -1.743 | -0.7415 | Yes |
| 20 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35447 | -1.747 | -0.7244 | Yes |
| 21 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 35469 | -1.759 | -0.7076 | Yes |
| 22 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35559 | -1.810 | -0.6921 | Yes |
| 23 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35608 | -1.839 | -0.6752 | Yes |
| 24 | HELLS | helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861] | 35644 | -1.871 | -0.6577 | Yes |
| 25 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35653 | -1.875 | -0.6394 | Yes |
| 26 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35704 | -1.908 | -0.6219 | Yes |
| 27 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35769 | -1.949 | -0.6044 | Yes |
| 28 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35808 | -1.979 | -0.5859 | Yes |
| 29 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 35855 | -2.012 | -0.5672 | Yes |
| 30 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35939 | -2.080 | -0.5489 | Yes |
| 31 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35949 | -2.088 | -0.5286 | Yes |
| 32 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35971 | -2.105 | -0.5083 | Yes |
| 33 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35994 | -2.128 | -0.4879 | Yes |
| 34 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36061 | -2.182 | -0.4681 | Yes |
| 35 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36065 | -2.187 | -0.4466 | Yes |
| 36 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36102 | -2.226 | -0.4256 | Yes |
| 37 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36147 | -2.266 | -0.4044 | Yes |
| 38 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36291 | -2.397 | -0.3846 | Yes |
| 39 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 36323 | -2.430 | -0.3614 | Yes |
| 40 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36336 | -2.447 | -0.3376 | Yes |
| 41 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36338 | -2.450 | -0.3134 | Yes |
| 42 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36341 | -2.453 | -0.2893 | Yes |
| 43 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36418 | -2.536 | -0.2663 | Yes |
| 44 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36429 | -2.546 | -0.2414 | Yes |
| 45 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36468 | -2.596 | -0.2168 | Yes |
| 46 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36492 | -2.640 | -0.1913 | Yes |
| 47 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36641 | -2.835 | -0.1673 | Yes |
| 48 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36657 | -2.858 | -0.1395 | Yes |
| 49 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36694 | -2.936 | -0.1115 | Yes |
| 50 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36707 | -2.964 | -0.0825 | Yes |
| 51 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36708 | -2.969 | -0.0532 | Yes |
| 52 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36716 | -2.984 | -0.0239 | Yes |
| 53 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36895 | -3.442 | 0.0053 | Yes |
