Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_PCNA |
| Enrichment Score (ES) | -0.85058695 |
| Normalized Enrichment Score (NES) | -1.7507397 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1522 | 1.100 | -0.0326 | No |
| 2 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 1600 | 1.066 | -0.0264 | No |
| 3 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2035 | 0.878 | -0.0313 | No |
| 4 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 2973 | 0.593 | -0.0520 | No |
| 5 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26185 | 0.000 | -0.6790 | No |
| 6 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27890 | -0.049 | -0.7246 | No |
| 7 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30286 | -0.341 | -0.7867 | No |
| 8 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31668 | -0.553 | -0.8197 | No |
| 9 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32050 | -0.618 | -0.8252 | No |
| 10 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 32434 | -0.702 | -0.8301 | No |
| 11 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33018 | -0.836 | -0.8394 | No |
| 12 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33435 | -0.948 | -0.8432 | Yes |
| 13 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33703 | -1.035 | -0.8424 | Yes |
| 14 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33875 | -1.087 | -0.8386 | Yes |
| 15 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34299 | -1.231 | -0.8405 | Yes |
| 16 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34419 | -1.276 | -0.8338 | Yes |
| 17 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 34657 | -1.375 | -0.8296 | Yes |
| 18 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34678 | -1.382 | -0.8194 | Yes |
| 19 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34692 | -1.386 | -0.8090 | Yes |
| 20 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34760 | -1.422 | -0.7998 | Yes |
| 21 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 34850 | -1.453 | -0.7909 | Yes |
| 22 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34948 | -1.490 | -0.7820 | Yes |
| 23 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35150 | -1.587 | -0.7751 | Yes |
| 24 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35283 | -1.667 | -0.7658 | Yes |
| 25 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35385 | -1.715 | -0.7552 | Yes |
| 26 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 35469 | -1.759 | -0.7438 | Yes |
| 27 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35471 | -1.761 | -0.7302 | Yes |
| 28 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35498 | -1.774 | -0.7171 | Yes |
| 29 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35559 | -1.810 | -0.7047 | Yes |
| 30 | PAXIP1 | PAX interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:8624] | 35580 | -1.826 | -0.6911 | Yes |
| 31 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35602 | -1.838 | -0.6774 | Yes |
| 32 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35608 | -1.839 | -0.6633 | Yes |
| 33 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35704 | -1.908 | -0.6511 | Yes |
| 34 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35709 | -1.910 | -0.6364 | Yes |
| 35 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35769 | -1.949 | -0.6229 | Yes |
| 36 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35808 | -1.979 | -0.6085 | Yes |
| 37 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35905 | -2.049 | -0.5953 | Yes |
| 38 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35939 | -2.080 | -0.5800 | Yes |
| 39 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35949 | -2.088 | -0.5641 | Yes |
| 40 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35971 | -2.105 | -0.5483 | Yes |
| 41 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36028 | -2.161 | -0.5331 | Yes |
| 42 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36061 | -2.182 | -0.5170 | Yes |
| 43 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36065 | -2.187 | -0.5002 | Yes |
| 44 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36102 | -2.226 | -0.4839 | Yes |
| 45 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36111 | -2.235 | -0.4668 | Yes |
| 46 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36147 | -2.266 | -0.4502 | Yes |
| 47 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36174 | -2.293 | -0.4331 | Yes |
| 48 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36182 | -2.302 | -0.4154 | Yes |
| 49 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36291 | -2.397 | -0.3998 | Yes |
| 50 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 36323 | -2.430 | -0.3818 | Yes |
| 51 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36336 | -2.447 | -0.3631 | Yes |
| 52 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36418 | -2.536 | -0.3457 | Yes |
| 53 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36429 | -2.546 | -0.3262 | Yes |
| 54 | KIF15 | kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273] | 36451 | -2.572 | -0.3068 | Yes |
| 55 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36468 | -2.596 | -0.2871 | Yes |
| 56 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36471 | -2.598 | -0.2670 | Yes |
| 57 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36474 | -2.605 | -0.2469 | Yes |
| 58 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36492 | -2.640 | -0.2269 | Yes |
| 59 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36530 | -2.698 | -0.2070 | Yes |
| 60 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36617 | -2.804 | -0.1876 | Yes |
| 61 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36641 | -2.835 | -0.1662 | Yes |
| 62 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36694 | -2.936 | -0.1449 | Yes |
| 63 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36707 | -2.964 | -0.1222 | Yes |
| 64 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36716 | -2.984 | -0.0993 | Yes |
| 65 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36799 | -3.202 | -0.0767 | Yes |
| 66 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36895 | -3.442 | -0.0526 | Yes |
| 67 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36896 | -3.444 | -0.0259 | Yes |
| 68 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 37028 | -4.011 | 0.0017 | Yes |
