Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_RRM2 |
| Enrichment Score (ES) | -0.89179283 |
| Normalized Enrichment Score (NES) | -1.6882122 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.295336E-4 |
| FWER p-Value | 0.005 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26185 | 0.000 | -0.7067 | No |
| 2 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27890 | -0.049 | -0.7521 | No |
| 3 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 32873 | -0.802 | -0.8763 | Yes |
| 4 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33018 | -0.836 | -0.8694 | Yes |
| 5 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33435 | -0.948 | -0.8685 | Yes |
| 6 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34299 | -1.231 | -0.8760 | Yes |
| 7 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34678 | -1.382 | -0.8685 | Yes |
| 8 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34760 | -1.422 | -0.8524 | Yes |
| 9 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 34850 | -1.453 | -0.8362 | Yes |
| 10 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34948 | -1.490 | -0.8197 | Yes |
| 11 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35100 | -1.565 | -0.8037 | Yes |
| 12 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35283 | -1.667 | -0.7872 | Yes |
| 13 | SMC1A | structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111] | 35336 | -1.691 | -0.7669 | Yes |
| 14 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35447 | -1.747 | -0.7475 | Yes |
| 15 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 35469 | -1.759 | -0.7255 | Yes |
| 16 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35498 | -1.774 | -0.7035 | Yes |
| 17 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35559 | -1.810 | -0.6819 | Yes |
| 18 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35704 | -1.908 | -0.6613 | Yes |
| 19 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35769 | -1.949 | -0.6380 | Yes |
| 20 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35808 | -1.979 | -0.6137 | Yes |
| 21 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35949 | -2.088 | -0.5907 | Yes |
| 22 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35971 | -2.105 | -0.5642 | Yes |
| 23 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35994 | -2.128 | -0.5375 | Yes |
| 24 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36065 | -2.187 | -0.5113 | Yes |
| 25 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36111 | -2.235 | -0.4839 | Yes |
| 26 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36147 | -2.266 | -0.4558 | Yes |
| 27 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36291 | -2.397 | -0.4289 | Yes |
| 28 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36336 | -2.447 | -0.3987 | Yes |
| 29 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36338 | -2.450 | -0.3673 | Yes |
| 30 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36341 | -2.453 | -0.3359 | Yes |
| 31 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36418 | -2.536 | -0.3054 | Yes |
| 32 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36468 | -2.596 | -0.2734 | Yes |
| 33 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36471 | -2.598 | -0.2401 | Yes |
| 34 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36474 | -2.605 | -0.2068 | Yes |
| 35 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36492 | -2.640 | -0.1734 | Yes |
| 36 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36530 | -2.698 | -0.1398 | Yes |
| 37 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36617 | -2.804 | -0.1061 | Yes |
| 38 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36641 | -2.835 | -0.0704 | Yes |
| 39 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36716 | -2.984 | -0.0341 | Yes |
| 40 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36895 | -3.442 | 0.0053 | Yes |
