Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_TTK |
| Enrichment Score (ES) | -0.8652821 |
| Normalized Enrichment Score (NES) | -1.6380516 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0010582315 |
| FWER p-Value | 0.021 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1522 | 1.100 | -0.0251 | No |
| 2 | CCT2 | chaperonin containing TCP1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:1615] | 5187 | 0.205 | -0.1211 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26185 | 0.000 | -0.6878 | No |
| 4 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27890 | -0.049 | -0.7330 | No |
| 5 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 31702 | -0.560 | -0.8278 | No |
| 6 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32050 | -0.618 | -0.8282 | No |
| 7 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 33018 | -0.836 | -0.8422 | No |
| 8 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33875 | -1.087 | -0.8495 | Yes |
| 9 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34299 | -1.231 | -0.8431 | Yes |
| 10 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34419 | -1.276 | -0.8278 | Yes |
| 11 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34692 | -1.386 | -0.8151 | Yes |
| 12 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34760 | -1.422 | -0.7963 | Yes |
| 13 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 34917 | -1.480 | -0.7791 | Yes |
| 14 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34948 | -1.490 | -0.7583 | Yes |
| 15 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35135 | -1.581 | -0.7404 | Yes |
| 16 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35150 | -1.587 | -0.7178 | Yes |
| 17 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35385 | -1.715 | -0.6993 | Yes |
| 18 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35559 | -1.810 | -0.6777 | Yes |
| 19 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35602 | -1.838 | -0.6522 | Yes |
| 20 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35704 | -1.908 | -0.6273 | Yes |
| 21 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35707 | -1.910 | -0.5997 | Yes |
| 22 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35709 | -1.910 | -0.5720 | Yes |
| 23 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35769 | -1.949 | -0.5454 | Yes |
| 24 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35808 | -1.979 | -0.5177 | Yes |
| 25 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35949 | -2.088 | -0.4913 | Yes |
| 26 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35971 | -2.105 | -0.4613 | Yes |
| 27 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36061 | -2.182 | -0.4321 | Yes |
| 28 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36102 | -2.226 | -0.4009 | Yes |
| 29 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36147 | -2.266 | -0.3693 | Yes |
| 30 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36291 | -2.397 | -0.3384 | Yes |
| 31 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36336 | -2.447 | -0.3042 | Yes |
| 32 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36418 | -2.536 | -0.2696 | Yes |
| 33 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36429 | -2.546 | -0.2330 | Yes |
| 34 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36471 | -2.598 | -0.1965 | Yes |
| 35 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36492 | -2.640 | -0.1588 | Yes |
| 36 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36617 | -2.804 | -0.1215 | Yes |
| 37 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36641 | -2.835 | -0.0810 | Yes |
| 38 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36716 | -2.984 | -0.0398 | Yes |
| 39 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36895 | -3.442 | 0.0053 | Yes |
