Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | MODULE_121 |
| Enrichment Score (ES) | 0.5925493 |
| Normalized Enrichment Score (NES) | 1.5134615 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.25967222 |
| FWER p-Value | 0.92 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.990 | 0.0469 | Yes |
| 2 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 4 | 4.930 | 0.0932 | Yes |
| 3 | VEGFC | vascular endothelial growth factor C [Source:HGNC Symbol;Acc:HGNC:12682] | 9 | 4.793 | 0.1382 | Yes |
| 4 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 37 | 4.309 | 0.1780 | Yes |
| 5 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 44 | 4.198 | 0.2173 | Yes |
| 6 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 47 | 4.168 | 0.2564 | Yes |
| 7 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 49 | 4.118 | 0.2951 | Yes |
| 8 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 57 | 4.035 | 0.3328 | Yes |
| 9 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 72 | 3.866 | 0.3688 | Yes |
| 10 | BCAT1 | branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] | 249 | 2.698 | 0.3894 | Yes |
| 11 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 277 | 2.597 | 0.4131 | Yes |
| 12 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 284 | 2.578 | 0.4372 | Yes |
| 13 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 292 | 2.541 | 0.4609 | Yes |
| 14 | TSPAN3 | tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752] | 441 | 2.167 | 0.4773 | Yes |
| 15 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 594 | 1.884 | 0.4909 | Yes |
| 16 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 758 | 1.641 | 0.5019 | Yes |
| 17 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 819 | 1.576 | 0.5151 | Yes |
| 18 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 847 | 1.549 | 0.5290 | Yes |
| 19 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 930 | 1.474 | 0.5406 | Yes |
| 20 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 958 | 1.451 | 0.5535 | Yes |
| 21 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 1180 | 1.276 | 0.5595 | Yes |
| 22 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 1263 | 1.218 | 0.5688 | Yes |
| 23 | PSPHP1 | phosphoserine phosphatase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9578] | 1351 | 1.179 | 0.5775 | Yes |
| 24 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1402 | 1.156 | 0.5870 | Yes |
| 25 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1573 | 1.076 | 0.5925 | Yes |
| 26 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 2056 | 0.871 | 0.5877 | No |
| 27 | HBEGF | heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059] | 2465 | 0.732 | 0.5836 | No |
| 28 | ZEB1 | zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642] | 2493 | 0.723 | 0.5896 | No |
| 29 | MXD1 | MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761] | 2913 | 0.611 | 0.5840 | No |
| 30 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 3079 | 0.576 | 0.5850 | No |
| 31 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 4084 | 0.383 | 0.5615 | No |
| 32 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 4753 | 0.271 | 0.5459 | No |
| 33 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 4799 | 0.264 | 0.5472 | No |
| 34 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 5492 | 0.160 | 0.5300 | No |
| 35 | FGF7 | fibroblast growth factor 7 [Source:HGNC Symbol;Acc:HGNC:3685] | 6026 | 0.088 | 0.5164 | No |
| 36 | IL6R | interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019] | 6154 | 0.072 | 0.5137 | No |
| 37 | AKR1C3 | aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386] | 6321 | 0.052 | 0.5097 | No |
| 38 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6710 | 0.000 | 0.4992 | No |
| 39 | AREG | amphiregulin [Source:HGNC Symbol;Acc:HGNC:651] | 7611 | 0.000 | 0.4749 | No |
| 40 | PDGFRA | platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803] | 7833 | 0.000 | 0.4689 | No |
| 41 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9128 | 0.000 | 0.4339 | No |
| 42 | GRPR | gastrin releasing peptide receptor [Source:HGNC Symbol;Acc:HGNC:4609] | 10274 | 0.000 | 0.4030 | No |
| 43 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11212 | 0.000 | 0.3776 | No |
| 44 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 12223 | 0.000 | 0.3503 | No |
| 45 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12657 | 0.000 | 0.3386 | No |
| 46 | IGF2 | insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] | 12673 | 0.000 | 0.3382 | No |
| 47 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12674 | 0.000 | 0.3382 | No |
| 48 | VIP | vasoactive intestinal peptide [Source:HGNC Symbol;Acc:HGNC:12693] | 13359 | 0.000 | 0.3197 | No |
| 49 | VIPR1 | vasoactive intestinal peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:12694] | 13560 | 0.000 | 0.3143 | No |
| 50 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13970 | 0.000 | 0.3033 | No |
| 51 | IL15RA | interleukin 15 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5978] | 14330 | 0.000 | 0.2936 | No |
| 52 | TACSTD2 | tumor associated calcium signal transducer 2 [Source:HGNC Symbol;Acc:HGNC:11530] | 14648 | 0.000 | 0.2850 | No |
| 53 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15858 | 0.000 | 0.2523 | No |
| 54 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15859 | 0.000 | 0.2523 | No |
| 55 | MST1R | macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381] | 16341 | 0.000 | 0.2393 | No |
| 56 | FGA | fibrinogen alpha chain [Source:HGNC Symbol;Acc:HGNC:3661] | 16752 | 0.000 | 0.2282 | No |
| 57 | FGG | fibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694] | 16753 | 0.000 | 0.2282 | No |
| 58 | GCG | glucagon [Source:HGNC Symbol;Acc:HGNC:4191] | 16992 | 0.000 | 0.2218 | No |
| 59 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17119 | 0.000 | 0.2184 | No |
| 60 | IL3 | interleukin 3 [Source:HGNC Symbol;Acc:HGNC:6011] | 17754 | 0.000 | 0.2012 | No |
| 61 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 17855 | 0.000 | 0.1985 | No |
| 62 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18985 | 0.000 | 0.1680 | No |
| 63 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19433 | 0.000 | 0.1559 | No |
| 64 | PTN | pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630] | 20099 | 0.000 | 0.1380 | No |
| 65 | EDNRA | endothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179] | 21910 | 0.000 | 0.0890 | No |
| 66 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 22276 | 0.000 | 0.0792 | No |
| 67 | CCN1 | cellular communication network factor 1 [Source:HGNC Symbol;Acc:HGNC:2654] | 22967 | 0.000 | 0.0605 | No |
| 68 | SLAMF1 | signaling lymphocytic activation molecule family member 1 [Source:HGNC Symbol;Acc:HGNC:10903] | 23001 | 0.000 | 0.0596 | No |
| 69 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 23116 | 0.000 | 0.0565 | No |
| 70 | CD8A | CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706] | 23117 | 0.000 | 0.0565 | No |
| 71 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24566 | 0.000 | 0.0174 | No |
| 72 | FGF4 | fibroblast growth factor 4 [Source:HGNC Symbol;Acc:HGNC:3682] | 25436 | 0.000 | -0.0061 | No |
| 73 | REG1B | regenerating family member 1 beta [Source:HGNC Symbol;Acc:HGNC:9952] | 26413 | 0.000 | -0.0325 | No |
| 74 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 27731 | -0.030 | -0.0678 | No |
| 75 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 27938 | -0.056 | -0.0729 | No |
| 76 | EPHB4 | EPH receptor B4 [Source:HGNC Symbol;Acc:HGNC:3395] | 29530 | -0.244 | -0.1136 | No |
| 77 | CSRP2 | cysteine and glycine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470] | 29620 | -0.256 | -0.1136 | No |
| 78 | EGF | epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229] | 30174 | -0.327 | -0.1254 | No |
| 79 | FGB | fibrinogen beta chain [Source:HGNC Symbol;Acc:HGNC:3662] | 30848 | -0.419 | -0.1397 | No |
| 80 | CDK5R1 | cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775] | 32471 | -0.709 | -0.1769 | No |
| 81 | IGF1 | insulin like growth factor 1 [Source:HGNC Symbol;Acc:HGNC:5464] | 32568 | -0.728 | -0.1726 | No |
| 82 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 32922 | -0.814 | -0.1745 | No |
| 83 | SFN | stratifin [Source:HGNC Symbol;Acc:HGNC:10773] | 33221 | -0.892 | -0.1742 | No |
| 84 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 33517 | -0.972 | -0.1730 | No |
| 85 | INSIG1 | insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083] | 33959 | -1.115 | -0.1745 | No |
| 86 | GRN | granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601] | 33984 | -1.123 | -0.1645 | No |
| 87 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 34229 | -1.206 | -0.1598 | No |
| 88 | TGFB3 | transforming growth factor beta 3 [Source:HGNC Symbol;Acc:HGNC:11769] | 34505 | -1.314 | -0.1549 | No |
| 89 | GAS6 | growth arrest specific 6 [Source:HGNC Symbol;Acc:HGNC:4168] | 34612 | -1.360 | -0.1449 | No |
| 90 | CREG1 | cellular repressor of E1A stimulated genes 1 [Source:HGNC Symbol;Acc:HGNC:2351] | 34623 | -1.364 | -0.1324 | No |
| 91 | RUNX3 | RUNX family transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473] | 35024 | -1.528 | -0.1288 | No |
| 92 | MAPRE2 | microtubule associated protein RP/EB family member 2 [Source:HGNC Symbol;Acc:HGNC:6891] | 35563 | -1.814 | -0.1263 | No |
| 93 | EMP1 | epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] | 35655 | -1.877 | -0.1111 | No |
| 94 | LRP1 | LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692] | 35671 | -1.882 | -0.0938 | No |
| 95 | EPS8 | epidermal growth factor receptor pathway substrate 8 [Source:HGNC Symbol;Acc:HGNC:3420] | 36200 | -2.317 | -0.0863 | No |
| 96 | ZFP36L2 | ZFP36 ring finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:1108] | 36214 | -2.330 | -0.0648 | No |
| 97 | CRIP1 | cysteine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2360] | 36611 | -2.790 | -0.0492 | No |
| 98 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 36732 | -3.016 | -0.0241 | No |
| 99 | BCAR1 | BCAR1 scaffold protein, Cas family member [Source:HGNC Symbol;Acc:HGNC:971] | 36935 | -3.592 | 0.0042 | No |
