Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | MODULE_345 |
| Enrichment Score (ES) | 0.61322206 |
| Normalized Enrichment Score (NES) | 1.6231143 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.14371054 |
| FWER p-Value | 0.55 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 4 | 4.930 | 0.0465 | Yes |
| 2 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 31 | 4.386 | 0.0873 | Yes |
| 3 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 63 | 3.976 | 0.1240 | Yes |
| 4 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 64 | 3.975 | 0.1616 | Yes |
| 5 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 77 | 3.745 | 0.1967 | Yes |
| 6 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 143 | 3.206 | 0.2252 | Yes |
| 7 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 173 | 3.047 | 0.2533 | Yes |
| 8 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 178 | 3.031 | 0.2818 | Yes |
| 9 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 183 | 3.012 | 0.3102 | Yes |
| 10 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 234 | 2.745 | 0.3348 | Yes |
| 11 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 285 | 2.574 | 0.3578 | Yes |
| 12 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 305 | 2.496 | 0.3809 | Yes |
| 13 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 391 | 2.293 | 0.4002 | Yes |
| 14 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 432 | 2.194 | 0.4199 | Yes |
| 15 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 457 | 2.138 | 0.4395 | Yes |
| 16 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 469 | 2.107 | 0.4591 | Yes |
| 17 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 506 | 2.036 | 0.4774 | Yes |
| 18 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 587 | 1.904 | 0.4932 | Yes |
| 19 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 595 | 1.883 | 0.5108 | Yes |
| 20 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 722 | 1.688 | 0.5234 | Yes |
| 21 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 954 | 1.453 | 0.5309 | Yes |
| 22 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 958 | 1.451 | 0.5445 | Yes |
| 23 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 977 | 1.436 | 0.5576 | Yes |
| 24 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 1061 | 1.366 | 0.5683 | Yes |
| 25 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 1136 | 1.303 | 0.5786 | Yes |
| 26 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 1169 | 1.286 | 0.5899 | Yes |
| 27 | FCRL2 | Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875] | 1288 | 1.209 | 0.5981 | Yes |
| 28 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 1593 | 1.067 | 0.6000 | Yes |
| 29 | BLNK | B cell linker [Source:HGNC Symbol;Acc:HGNC:14211] | 1620 | 1.053 | 0.6092 | Yes |
| 30 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1808 | 0.959 | 0.6132 | Yes |
| 31 | ZNF436 | zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814] | 2472 | 0.730 | 0.6022 | No |
| 32 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 2626 | 0.683 | 0.6045 | No |
| 33 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 2879 | 0.622 | 0.6036 | No |
| 34 | CD79B | CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699] | 3588 | 0.474 | 0.5889 | No |
| 35 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 3990 | 0.398 | 0.5818 | No |
| 36 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 4002 | 0.397 | 0.5853 | No |
| 37 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 4132 | 0.371 | 0.5853 | No |
| 38 | SPIB | Spi-B transcription factor [Source:HGNC Symbol;Acc:HGNC:11242] | 4159 | 0.368 | 0.5881 | No |
| 39 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 4332 | 0.340 | 0.5866 | No |
| 40 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 4396 | 0.329 | 0.5880 | No |
| 41 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 4407 | 0.327 | 0.5909 | No |
| 42 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 4591 | 0.299 | 0.5887 | No |
| 43 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 5243 | 0.197 | 0.5730 | No |
| 44 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 5255 | 0.195 | 0.5745 | No |
| 45 | MECP2 | methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990] | 6674 | 0.000 | 0.5362 | No |
| 46 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6732 | 0.000 | 0.5346 | No |
| 47 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 7152 | 0.000 | 0.5233 | No |
| 48 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 7480 | 0.000 | 0.5144 | No |
| 49 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 9340 | 0.000 | 0.4642 | No |
| 50 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9941 | 0.000 | 0.4479 | No |
| 51 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 10130 | 0.000 | 0.4428 | No |
| 52 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 10196 | 0.000 | 0.4411 | No |
| 53 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 10201 | 0.000 | 0.4410 | No |
| 54 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 10342 | 0.000 | 0.4372 | No |
| 55 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10819 | 0.000 | 0.4243 | No |
| 56 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 11317 | 0.000 | 0.4109 | No |
| 57 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 12451 | 0.000 | 0.3802 | No |
| 58 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12640 | 0.000 | 0.3751 | No |
| 59 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12644 | 0.000 | 0.3750 | No |
| 60 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12674 | 0.000 | 0.3743 | No |
| 61 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12710 | 0.000 | 0.3733 | No |
| 62 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13263 | 0.000 | 0.3584 | No |
| 63 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 14034 | 0.000 | 0.3375 | No |
| 64 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14796 | 0.000 | 0.3170 | No |
| 65 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15738 | 0.000 | 0.2915 | No |
| 66 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15858 | 0.000 | 0.2883 | No |
| 67 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16268 | 0.000 | 0.2772 | No |
| 68 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16297 | 0.000 | 0.2765 | No |
| 69 | MST1L | macrophage stimulating 1 like [Source:HGNC Symbol;Acc:HGNC:7390] | 16342 | 0.000 | 0.2753 | No |
| 70 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16589 | 0.000 | 0.2686 | No |
| 71 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16599 | 0.000 | 0.2684 | No |
| 72 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17217 | 0.000 | 0.2517 | No |
| 73 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17824 | 0.000 | 0.2353 | No |
| 74 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18399 | 0.000 | 0.2198 | No |
| 75 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18418 | 0.000 | 0.2193 | No |
| 76 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18447 | 0.000 | 0.2185 | No |
| 77 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18844 | 0.000 | 0.2078 | No |
| 78 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 18865 | 0.000 | 0.2073 | No |
| 79 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18886 | 0.000 | 0.2067 | No |
| 80 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19421 | 0.000 | 0.1923 | No |
| 81 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20610 | 0.000 | 0.1601 | No |
| 82 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 20811 | 0.000 | 0.1547 | No |
| 83 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22451 | 0.000 | 0.1104 | No |
| 84 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22932 | 0.000 | 0.0974 | No |
| 85 | CD19 | CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633] | 22995 | 0.000 | 0.0957 | No |
| 86 | CD27 | CD27 molecule [Source:HGNC Symbol;Acc:HGNC:11922] | 23012 | 0.000 | 0.0953 | No |
| 87 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 23023 | 0.000 | 0.0950 | No |
| 88 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 23455 | 0.000 | 0.0834 | No |
| 89 | UCP1 | uncoupling protein 1 [Source:HGNC Symbol;Acc:HGNC:12517] | 23485 | 0.000 | 0.0826 | No |
| 90 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 23571 | 0.000 | 0.0803 | No |
| 91 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23719 | 0.000 | 0.0763 | No |
| 92 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 24414 | 0.000 | 0.0575 | No |
| 93 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 25093 | 0.000 | 0.0392 | No |
| 94 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 25101 | 0.000 | 0.0390 | No |
| 95 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 25573 | 0.000 | 0.0263 | No |
| 96 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 25846 | 0.000 | 0.0189 | No |
| 97 | SLC22A23 | solute carrier family 22 member 23 [Source:HGNC Symbol;Acc:HGNC:21106] | 26762 | 0.000 | -0.0059 | No |
| 98 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 27572 | -0.009 | -0.0277 | No |
| 99 | UNC13B | unc-13 homolog B [Source:HGNC Symbol;Acc:HGNC:12566] | 27692 | -0.025 | -0.0306 | No |
| 100 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 27938 | -0.056 | -0.0367 | No |
| 101 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 28206 | -0.085 | -0.0432 | No |
| 102 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 28442 | -0.112 | -0.0485 | No |
| 103 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 28619 | -0.132 | -0.0520 | No |
| 104 | CD37 | CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666] | 29258 | -0.212 | -0.0672 | No |
| 105 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 29517 | -0.243 | -0.0719 | No |
| 106 | UNKL | unk like zinc finger [Source:HGNC Symbol;Acc:HGNC:14184] | 30104 | -0.317 | -0.0848 | No |
| 107 | FCRLA | Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504] | 30200 | -0.330 | -0.0842 | No |
| 108 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 31024 | -0.444 | -0.1023 | No |
| 109 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 31061 | -0.449 | -0.0990 | No |
| 110 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 31085 | -0.452 | -0.0954 | No |
| 111 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 31241 | -0.476 | -0.0950 | No |
| 112 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 31827 | -0.580 | -0.1054 | No |
| 113 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 32408 | -0.696 | -0.1145 | No |
| 114 | RUBCNL | rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420] | 32627 | -0.740 | -0.1134 | No |
| 115 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 33131 | -0.866 | -0.1188 | No |
| 116 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 33362 | -0.930 | -0.1163 | No |
| 117 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 34120 | -1.171 | -0.1257 | No |
| 118 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 34385 | -1.262 | -0.1209 | No |
| 119 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 34610 | -1.360 | -0.1141 | No |
| 120 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 35245 | -1.643 | -0.1157 | No |
| 121 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 35828 | -1.996 | -0.1126 | No |
| 122 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36140 | -2.261 | -0.0996 | No |
| 123 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36417 | -2.535 | -0.0831 | No |
| 124 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 36662 | -2.866 | -0.0626 | No |
| 125 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36966 | -3.722 | -0.0356 | No |
| 126 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 37043 | -4.119 | 0.0013 | No |
