Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | MODULE_76 |
| Enrichment Score (ES) | 0.7354747 |
| Normalized Enrichment Score (NES) | 1.8247542 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.04353142 |
| FWER p-Value | 0.027 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.990 | 0.0652 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 3 | 4.934 | 0.1297 | Yes |
| 3 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 11 | 4.769 | 0.1919 | Yes |
| 4 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 13 | 4.731 | 0.2537 | Yes |
| 5 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 57 | 4.035 | 0.3053 | Yes |
| 6 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 69 | 3.916 | 0.3562 | Yes |
| 7 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 90 | 3.616 | 0.4029 | Yes |
| 8 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 116 | 3.430 | 0.4471 | Yes |
| 9 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 220 | 2.811 | 0.4811 | Yes |
| 10 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 285 | 2.574 | 0.5130 | Yes |
| 11 | TLR1 | toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847] | 357 | 2.375 | 0.5421 | Yes |
| 12 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 472 | 2.099 | 0.5665 | Yes |
| 13 | TIRAP | TIR domain containing adaptor protein [Source:HGNC Symbol;Acc:HGNC:17192] | 495 | 2.056 | 0.5928 | Yes |
| 14 | TLR3 | toll like receptor 3 [Source:HGNC Symbol;Acc:HGNC:11849] | 796 | 1.601 | 0.6056 | Yes |
| 15 | ANXA1 | annexin A1 [Source:HGNC Symbol;Acc:HGNC:533] | 913 | 1.493 | 0.6220 | Yes |
| 16 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 973 | 1.438 | 0.6392 | Yes |
| 17 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1022 | 1.395 | 0.6561 | Yes |
| 18 | FPR2 | formyl peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:3827] | 1348 | 1.180 | 0.6628 | Yes |
| 19 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1573 | 1.076 | 0.6708 | Yes |
| 20 | AOC3 | amine oxidase copper containing 3 [Source:HGNC Symbol;Acc:HGNC:550] | 1672 | 1.026 | 0.6816 | Yes |
| 21 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1808 | 0.959 | 0.6904 | Yes |
| 22 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 2056 | 0.871 | 0.6951 | Yes |
| 23 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 2084 | 0.861 | 0.7057 | Yes |
| 24 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 2140 | 0.843 | 0.7152 | Yes |
| 25 | ADORA2A | adenosine A2a receptor [Source:HGNC Symbol;Acc:HGNC:263] | 2348 | 0.770 | 0.7197 | Yes |
| 26 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 2506 | 0.720 | 0.7249 | Yes |
| 27 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 2511 | 0.717 | 0.7341 | Yes |
| 28 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2775 | 0.646 | 0.7355 | Yes |
| 29 | AOX1 | aldehyde oxidase 1 [Source:HGNC Symbol;Acc:HGNC:553] | 3885 | 0.421 | 0.7110 | No |
| 30 | ABCF1 | ATP binding cassette subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:70] | 3890 | 0.419 | 0.7164 | No |
| 31 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 4513 | 0.310 | 0.7036 | No |
| 32 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4624 | 0.294 | 0.7045 | No |
| 33 | AOAH | acyloxyacyl hydrolase [Source:HGNC Symbol;Acc:HGNC:548] | 4635 | 0.292 | 0.7080 | No |
| 34 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 5333 | 0.183 | 0.6916 | No |
| 35 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 5574 | 0.149 | 0.6871 | No |
| 36 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 5920 | 0.104 | 0.6791 | No |
| 37 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 6078 | 0.083 | 0.6759 | No |
| 38 | LY75 | lymphocyte antigen 75 [Source:HGNC Symbol;Acc:HGNC:6729] | 6133 | 0.076 | 0.6755 | No |
| 39 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6711 | 0.000 | 0.6599 | No |
| 40 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6712 | 0.000 | 0.6599 | No |
| 41 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6731 | 0.000 | 0.6594 | No |
| 42 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6732 | 0.000 | 0.6594 | No |
| 43 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6734 | 0.000 | 0.6594 | No |
| 44 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6741 | 0.000 | 0.6592 | No |
| 45 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6743 | 0.000 | 0.6592 | No |
| 46 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8830 | 0.000 | 0.6028 | No |
| 47 | LY86 | lymphocyte antigen 86 [Source:HGNC Symbol;Acc:HGNC:16837] | 9497 | 0.000 | 0.5848 | No |
| 48 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10991 | 0.000 | 0.5445 | No |
| 49 | S100A12 | S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489] | 11922 | 0.000 | 0.5194 | No |
| 50 | PTX3 | pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692] | 12551 | 0.000 | 0.5024 | No |
| 51 | C4B | complement C4B (Chido blood group) [Source:HGNC Symbol;Acc:HGNC:1324] | 15743 | 0.000 | 0.4162 | No |
| 52 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15992 | 0.000 | 0.4095 | No |
| 53 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16191 | 0.000 | 0.4041 | No |
| 54 | ADORA1 | adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262] | 16829 | 0.000 | 0.3869 | No |
| 55 | MGLL | monoglyceride lipase [Source:HGNC Symbol;Acc:HGNC:17038] | 17206 | 0.000 | 0.3768 | No |
| 56 | IL9 | interleukin 9 [Source:HGNC Symbol;Acc:HGNC:6029] | 17757 | 0.000 | 0.3619 | No |
| 57 | BDKRB2 | bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030] | 17982 | 0.000 | 0.3558 | No |
| 58 | ORM1 | orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498] | 18635 | 0.000 | 0.3382 | No |
| 59 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18871 | 0.000 | 0.3319 | No |
| 60 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18906 | 0.000 | 0.3310 | No |
| 61 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18907 | 0.000 | 0.3310 | No |
| 62 | CXCR2 | C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027] | 19343 | 0.000 | 0.3192 | No |
| 63 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19419 | 0.000 | 0.3172 | No |
| 64 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19421 | 0.000 | 0.3171 | No |
| 65 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19424 | 0.000 | 0.3171 | No |
| 66 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19433 | 0.000 | 0.3169 | No |
| 67 | PLA2G7 | phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040] | 22126 | 0.000 | 0.2441 | No |
| 68 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22930 | 0.000 | 0.2224 | No |
| 69 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22932 | 0.000 | 0.2224 | No |
| 70 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27677 | -0.024 | 0.0945 | No |
| 71 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 28178 | -0.082 | 0.0821 | No |
| 72 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 29098 | -0.192 | 0.0598 | No |
| 73 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 29713 | -0.269 | 0.0467 | No |
| 74 | AIF1 | allograft inflammatory factor 1 [Source:HGNC Symbol;Acc:HGNC:352] | 29817 | -0.282 | 0.0476 | No |
| 75 | AGER | advanced glycosylation end-product specific receptor [Source:HGNC Symbol;Acc:HGNC:320] | 29878 | -0.291 | 0.0498 | No |
| 76 | CYBB | cytochrome b-245 beta chain [Source:HGNC Symbol;Acc:HGNC:2578] | 30488 | -0.365 | 0.0381 | No |
| 77 | NFATC4 | nuclear factor of activated T cells 4 [Source:HGNC Symbol;Acc:HGNC:7778] | 31152 | -0.462 | 0.0262 | No |
| 78 | CXCR4 | C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] | 33466 | -0.958 | -0.0237 | No |
| 79 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 34622 | -1.363 | -0.0371 | No |
| 80 | ALOX5AP | arachidonate 5-lipoxygenase activating protein [Source:HGNC Symbol;Acc:HGNC:436] | 36889 | -3.425 | -0.0536 | No |
| 81 | ALOX5 | arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435] | 37075 | -4.509 | 0.0004 | No |
