Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOBP_FATTY_ACID_BETA_OXIDATION |
| Enrichment Score (ES) | -0.76693916 |
| Normalized Enrichment Score (NES) | -1.5749698 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.12976554 |
| FWER p-Value | 0.923 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SESN2 | sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746] | 783 | 1.612 | -0.0027 | No |
| 2 | MECR | mitochondrial trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:19691] | 1101 | 1.329 | 0.0039 | No |
| 3 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 1294 | 1.204 | 0.0125 | No |
| 4 | MFSD2A | major facilitator superfamily domain containing 2A [Source:HGNC Symbol;Acc:HGNC:25897] | 3124 | 0.568 | -0.0304 | No |
| 5 | CPT1B | carnitine palmitoyltransferase 1B [Source:HGNC Symbol;Acc:HGNC:2329] | 3159 | 0.560 | -0.0250 | No |
| 6 | PPARD | peroxisome proliferator activated receptor delta [Source:HGNC Symbol;Acc:HGNC:9235] | 5080 | 0.221 | -0.0743 | No |
| 7 | ACOXL | acyl-CoA oxidase like [Source:HGNC Symbol;Acc:HGNC:25621] | 5588 | 0.148 | -0.0863 | No |
| 8 | AKT1 | AKT serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:391] | 6399 | 0.042 | -0.1077 | No |
| 9 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 8253 | 0.000 | -0.1578 | No |
| 10 | ADIPOQ | adiponectin, C1Q and collagen domain containing [Source:HGNC Symbol;Acc:HGNC:13633] | 8360 | 0.000 | -0.1606 | No |
| 11 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 11160 | 0.000 | -0.2362 | No |
| 12 | DECR1 | 2,4-dienoyl-CoA reductase 1 [Source:HGNC Symbol;Acc:HGNC:2753] | 12414 | 0.000 | -0.2701 | No |
| 13 | ACOX2 | acyl-CoA oxidase 2 [Source:HGNC Symbol;Acc:HGNC:120] | 12522 | 0.000 | -0.2730 | No |
| 14 | CNR1 | cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] | 12531 | 0.000 | -0.2732 | No |
| 15 | PLIN5 | perilipin 5 [Source:HGNC Symbol;Acc:HGNC:33196] | 15909 | 0.000 | -0.3644 | No |
| 16 | BDH2 | 3-hydroxybutyrate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:32389] | 16240 | 0.000 | -0.3733 | No |
| 17 | TWIST1 | twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428] | 17288 | 0.000 | -0.4016 | No |
| 18 | LEP | leptin [Source:HGNC Symbol;Acc:HGNC:6553] | 18523 | 0.000 | -0.4350 | No |
| 19 | IRS1 | insulin receptor substrate 1 [Source:HGNC Symbol;Acc:HGNC:6125] | 21812 | 0.000 | -0.5238 | No |
| 20 | IRS2 | insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126] | 21815 | 0.000 | -0.5238 | No |
| 21 | PPARA | peroxisome proliferator activated receptor alpha [Source:HGNC Symbol;Acc:HGNC:9232] | 24127 | 0.000 | -0.5863 | No |
| 22 | DECR2 | 2,4-dienoyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:2754] | 27667 | -0.023 | -0.6816 | No |
| 23 | ECHDC2 | enoyl-CoA hydratase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23408] | 27941 | -0.056 | -0.6884 | No |
| 24 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 29047 | -0.187 | -0.7161 | No |
| 25 | ACADVL | acyl-CoA dehydrogenase very long chain [Source:HGNC Symbol;Acc:HGNC:92] | 29561 | -0.247 | -0.7271 | No |
| 26 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 29723 | -0.270 | -0.7284 | No |
| 27 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 29820 | -0.283 | -0.7277 | No |
| 28 | FABP1 | fatty acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3555] | 30162 | -0.325 | -0.7332 | No |
| 29 | ETFA | electron transfer flavoprotein subunit alpha [Source:HGNC Symbol;Acc:HGNC:3481] | 30314 | -0.343 | -0.7334 | No |
| 30 | AKT2 | AKT serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:392] | 30417 | -0.357 | -0.7320 | No |
| 31 | ECI1 | enoyl-CoA delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:2703] | 31508 | -0.523 | -0.7555 | Yes |
| 32 | MCAT | malonyl-CoA-acyl carrier protein transacylase [Source:HGNC Symbol;Acc:HGNC:29622] | 31515 | -0.524 | -0.7497 | Yes |
| 33 | HADHA | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:4801] | 31922 | -0.594 | -0.7539 | Yes |
| 34 | ETFB | electron transfer flavoprotein subunit beta [Source:HGNC Symbol;Acc:HGNC:3482] | 32013 | -0.611 | -0.7493 | Yes |
| 35 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 32328 | -0.679 | -0.7500 | Yes |
| 36 | ACAD11 | acyl-CoA dehydrogenase family member 11 [Source:HGNC Symbol;Acc:HGNC:30211] | 32663 | -0.749 | -0.7505 | Yes |
| 37 | PEX7 | peroxisomal biogenesis factor 7 [Source:HGNC Symbol;Acc:HGNC:8860] | 32959 | -0.821 | -0.7491 | Yes |
| 38 | IVD | isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186] | 33622 | -1.005 | -0.7555 | Yes |
| 39 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 33769 | -1.054 | -0.7473 | Yes |
| 40 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 34112 | -1.167 | -0.7432 | Yes |
| 41 | ETFDH | electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483] | 34155 | -1.182 | -0.7309 | Yes |
| 42 | HADHB | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta [Source:HGNC Symbol;Acc:HGNC:4803] | 34278 | -1.225 | -0.7201 | Yes |
| 43 | CPT1C | carnitine palmitoyltransferase 1C [Source:HGNC Symbol;Acc:HGNC:18540] | 34279 | -1.225 | -0.7061 | Yes |
| 44 | AMACR | alpha-methylacyl-CoA racemase [Source:HGNC Symbol;Acc:HGNC:451] | 34591 | -1.350 | -0.6991 | Yes |
| 45 | ACADL | acyl-CoA dehydrogenase long chain [Source:HGNC Symbol;Acc:HGNC:88] | 34709 | -1.396 | -0.6863 | Yes |
| 46 | ECHDC1 | ethylmalonyl-CoA decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:21489] | 34731 | -1.407 | -0.6708 | Yes |
| 47 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 34741 | -1.410 | -0.6549 | Yes |
| 48 | ECHS1 | enoyl-CoA hydratase, short chain 1 [Source:HGNC Symbol;Acc:HGNC:3151] | 34861 | -1.457 | -0.6414 | Yes |
| 49 | ACAT1 | acetyl-CoA acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:93] | 34869 | -1.463 | -0.6249 | Yes |
| 50 | TYSND1 | trypsin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28531] | 34963 | -1.499 | -0.6103 | Yes |
| 51 | CPT2 | carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:2330] | 35092 | -1.561 | -0.5959 | Yes |
| 52 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 35106 | -1.567 | -0.5783 | Yes |
| 53 | ACAD10 | acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597] | 35152 | -1.589 | -0.5614 | Yes |
| 54 | ACAT2 | acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94] | 35246 | -1.644 | -0.5451 | Yes |
| 55 | ACACB | acetyl-CoA carboxylase beta [Source:HGNC Symbol;Acc:HGNC:85] | 35315 | -1.679 | -0.5277 | Yes |
| 56 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 35456 | -1.752 | -0.5115 | Yes |
| 57 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 35495 | -1.773 | -0.4922 | Yes |
| 58 | ABCD4 | ATP binding cassette subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:68] | 35538 | -1.802 | -0.4728 | Yes |
| 59 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 35589 | -1.831 | -0.4532 | Yes |
| 60 | ACADM | acyl-CoA dehydrogenase medium chain [Source:HGNC Symbol;Acc:HGNC:89] | 35661 | -1.880 | -0.4336 | Yes |
| 61 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 35756 | -1.942 | -0.4139 | Yes |
| 62 | ACADS | acyl-CoA dehydrogenase short chain [Source:HGNC Symbol;Acc:HGNC:90] | 35964 | -2.101 | -0.3955 | Yes |
| 63 | GCDH | glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189] | 36103 | -2.226 | -0.3738 | Yes |
| 64 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 36117 | -2.237 | -0.3485 | Yes |
| 65 | HSD17B10 | hydroxysteroid 17-beta dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:4800] | 36216 | -2.330 | -0.3245 | Yes |
| 66 | AUH | AU RNA binding methylglutaconyl-CoA hydratase [Source:HGNC Symbol;Acc:HGNC:890] | 36248 | -2.358 | -0.2984 | Yes |
| 67 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 36378 | -2.484 | -0.2735 | Yes |
| 68 | ACAA2 | acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83] | 36522 | -2.683 | -0.2467 | Yes |
| 69 | CROT | carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366] | 36602 | -2.781 | -0.2170 | Yes |
| 70 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 36661 | -2.866 | -0.1858 | Yes |
| 71 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36718 | -2.985 | -0.1532 | Yes |
| 72 | ETFBKMT | electron transfer flavoprotein subunit beta lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:28739] | 36751 | -3.059 | -0.1191 | Yes |
| 73 | HADH | hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799] | 36786 | -3.143 | -0.0840 | Yes |
| 74 | CPT1A | carnitine palmitoyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:2328] | 36893 | -3.439 | -0.0476 | Yes |
| 75 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37080 | -4.623 | 0.0003 | Yes |
