Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOBP_FATTY_ACID_CATABOLIC_PROCESS |
| Enrichment Score (ES) | -0.7578027 |
| Normalized Enrichment Score (NES) | -1.6307012 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.034882903 |
| FWER p-Value | 0.343 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SESN2 | sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746] | 783 | 1.612 | -0.0070 | No |
| 2 | MECR | mitochondrial trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:19691] | 1101 | 1.329 | -0.0039 | No |
| 3 | HAO1 | hydroxyacid oxidase 1 [Source:HGNC Symbol;Acc:HGNC:4809] | 1234 | 1.233 | 0.0034 | No |
| 4 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 1294 | 1.204 | 0.0123 | No |
| 5 | AIG1 | androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:21607] | 2052 | 0.872 | -0.0005 | No |
| 6 | MFSD2A | major facilitator superfamily domain containing 2A [Source:HGNC Symbol;Acc:HGNC:25897] | 3124 | 0.568 | -0.0244 | No |
| 7 | CPT1B | carnitine palmitoyltransferase 1B [Source:HGNC Symbol;Acc:HGNC:2329] | 3159 | 0.560 | -0.0204 | No |
| 8 | PPARD | peroxisome proliferator activated receptor delta [Source:HGNC Symbol;Acc:HGNC:9235] | 5080 | 0.221 | -0.0704 | No |
| 9 | ABHD1 | abhydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17553] | 5544 | 0.153 | -0.0816 | No |
| 10 | ACOXL | acyl-CoA oxidase like [Source:HGNC Symbol;Acc:HGNC:25621] | 5588 | 0.148 | -0.0814 | No |
| 11 | ABHD2 | abhydrolase domain containing 2, acylglycerol lipase [Source:HGNC Symbol;Acc:HGNC:18717] | 5859 | 0.113 | -0.0877 | No |
| 12 | ABHD3 | abhydrolase domain containing 3, phospholipase [Source:HGNC Symbol;Acc:HGNC:18718] | 6196 | 0.070 | -0.0962 | No |
| 13 | AKT1 | AKT serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:391] | 6399 | 0.042 | -0.1013 | No |
| 14 | PECR | peroxisomal trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:18281] | 6433 | 0.038 | -0.1019 | No |
| 15 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 8253 | 0.000 | -0.1510 | No |
| 16 | ADIPOQ | adiponectin, C1Q and collagen domain containing [Source:HGNC Symbol;Acc:HGNC:13633] | 8360 | 0.000 | -0.1539 | No |
| 17 | NUDT7 | nudix hydrolase 7 [Source:HGNC Symbol;Acc:HGNC:8054] | 8474 | 0.000 | -0.1570 | No |
| 18 | GLYATL2 | glycine-N-acyltransferase like 2 [Source:HGNC Symbol;Acc:HGNC:24178] | 10598 | 0.000 | -0.2144 | No |
| 19 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 11160 | 0.000 | -0.2295 | No |
| 20 | DECR1 | 2,4-dienoyl-CoA reductase 1 [Source:HGNC Symbol;Acc:HGNC:2753] | 12414 | 0.000 | -0.2634 | No |
| 21 | ACOX2 | acyl-CoA oxidase 2 [Source:HGNC Symbol;Acc:HGNC:120] | 12522 | 0.000 | -0.2663 | No |
| 22 | CNR1 | cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] | 12531 | 0.000 | -0.2665 | No |
| 23 | PCK1 | phosphoenolpyruvate carboxykinase 1 [Source:HGNC Symbol;Acc:HGNC:8724] | 15508 | 0.000 | -0.3470 | No |
| 24 | CEL | carboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848] | 15874 | 0.000 | -0.3569 | No |
| 25 | PLIN5 | perilipin 5 [Source:HGNC Symbol;Acc:HGNC:33196] | 15909 | 0.000 | -0.3578 | No |
| 26 | BDH2 | 3-hydroxybutyrate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:32389] | 16240 | 0.000 | -0.3667 | No |
| 27 | TWIST1 | twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428] | 17288 | 0.000 | -0.3950 | No |
| 28 | ADTRP | androgen dependent TFPI regulating protein [Source:HGNC Symbol;Acc:HGNC:21214] | 18470 | 0.000 | -0.4269 | No |
| 29 | LEP | leptin [Source:HGNC Symbol;Acc:HGNC:6553] | 18523 | 0.000 | -0.4283 | No |
| 30 | IRS1 | insulin receptor substrate 1 [Source:HGNC Symbol;Acc:HGNC:6125] | 21812 | 0.000 | -0.5172 | No |
| 31 | IRS2 | insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126] | 21815 | 0.000 | -0.5173 | No |
| 32 | PPARA | peroxisome proliferator activated receptor alpha [Source:HGNC Symbol;Acc:HGNC:9232] | 24127 | 0.000 | -0.5798 | No |
| 33 | HAO2 | hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] | 24921 | 0.000 | -0.6012 | No |
| 34 | PEX13 | peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855] | 27546 | -0.004 | -0.6721 | No |
| 35 | DECR2 | 2,4-dienoyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:2754] | 27667 | -0.023 | -0.6752 | No |
| 36 | ECHDC2 | enoyl-CoA hydratase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23408] | 27941 | -0.056 | -0.6821 | No |
| 37 | ILVBL | ilvB acetolactate synthase like [Source:HGNC Symbol;Acc:HGNC:6041] | 28448 | -0.113 | -0.6948 | No |
| 38 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 29047 | -0.187 | -0.7093 | No |
| 39 | ALDH3A2 | aldehyde dehydrogenase 3 family member A2 [Source:HGNC Symbol;Acc:HGNC:403] | 29135 | -0.197 | -0.7099 | No |
| 40 | ACADVL | acyl-CoA dehydrogenase very long chain [Source:HGNC Symbol;Acc:HGNC:92] | 29561 | -0.247 | -0.7192 | No |
| 41 | NUDT19 | nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036] | 29661 | -0.261 | -0.7196 | No |
| 42 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 29723 | -0.270 | -0.7189 | No |
| 43 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 29820 | -0.283 | -0.7190 | No |
| 44 | FABP1 | fatty acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3555] | 30162 | -0.325 | -0.7254 | No |
| 45 | ETFA | electron transfer flavoprotein subunit alpha [Source:HGNC Symbol;Acc:HGNC:3481] | 30314 | -0.343 | -0.7264 | No |
| 46 | AKT2 | AKT serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:392] | 30417 | -0.357 | -0.7261 | No |
| 47 | ECI1 | enoyl-CoA delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:2703] | 31508 | -0.523 | -0.7509 | No |
| 48 | MCAT | malonyl-CoA-acyl carrier protein transacylase [Source:HGNC Symbol;Acc:HGNC:29622] | 31515 | -0.524 | -0.7465 | No |
| 49 | HADHA | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:4801] | 31922 | -0.594 | -0.7523 | Yes |
| 50 | ETFB | electron transfer flavoprotein subunit beta [Source:HGNC Symbol;Acc:HGNC:3482] | 32013 | -0.611 | -0.7493 | Yes |
| 51 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 32328 | -0.679 | -0.7518 | Yes |
| 52 | MMAA | metabolism of cobalamin associated A [Source:HGNC Symbol;Acc:HGNC:18871] | 32369 | -0.687 | -0.7469 | Yes |
| 53 | SLC27A4 | solute carrier family 27 member 4 [Source:HGNC Symbol;Acc:HGNC:10998] | 32377 | -0.690 | -0.7410 | Yes |
| 54 | PHYH | phytanoyl-CoA 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:8940] | 32422 | -0.699 | -0.7361 | Yes |
| 55 | ACAD11 | acyl-CoA dehydrogenase family member 11 [Source:HGNC Symbol;Acc:HGNC:30211] | 32663 | -0.749 | -0.7360 | Yes |
| 56 | PEX7 | peroxisomal biogenesis factor 7 [Source:HGNC Symbol;Acc:HGNC:8860] | 32959 | -0.821 | -0.7367 | Yes |
| 57 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 33134 | -0.868 | -0.7338 | Yes |
| 58 | IVD | isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186] | 33622 | -1.005 | -0.7381 | Yes |
| 59 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 33769 | -1.054 | -0.7328 | Yes |
| 60 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 33829 | -1.073 | -0.7250 | Yes |
| 61 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 34112 | -1.167 | -0.7224 | Yes |
| 62 | LPIN2 | lipin 2 [Source:HGNC Symbol;Acc:HGNC:14450] | 34143 | -1.178 | -0.7128 | Yes |
| 63 | ETFDH | electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483] | 34155 | -1.182 | -0.7027 | Yes |
| 64 | HADHB | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta [Source:HGNC Symbol;Acc:HGNC:4803] | 34278 | -1.225 | -0.6953 | Yes |
| 65 | CPT1C | carnitine palmitoyltransferase 1C [Source:HGNC Symbol;Acc:HGNC:18540] | 34279 | -1.225 | -0.6845 | Yes |
| 66 | AMACR | alpha-methylacyl-CoA racemase [Source:HGNC Symbol;Acc:HGNC:451] | 34591 | -1.350 | -0.6810 | Yes |
| 67 | ACADL | acyl-CoA dehydrogenase long chain [Source:HGNC Symbol;Acc:HGNC:88] | 34709 | -1.396 | -0.6719 | Yes |
| 68 | ECHDC1 | ethylmalonyl-CoA decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:21489] | 34731 | -1.407 | -0.6602 | Yes |
| 69 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 34741 | -1.410 | -0.6480 | Yes |
| 70 | ECHS1 | enoyl-CoA hydratase, short chain 1 [Source:HGNC Symbol;Acc:HGNC:3151] | 34861 | -1.457 | -0.6384 | Yes |
| 71 | ACAT1 | acetyl-CoA acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:93] | 34869 | -1.463 | -0.6258 | Yes |
| 72 | TYSND1 | trypsin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28531] | 34963 | -1.499 | -0.6151 | Yes |
| 73 | ACBD5 | acyl-CoA binding domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23338] | 35018 | -1.525 | -0.6032 | Yes |
| 74 | CPT2 | carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:2330] | 35092 | -1.561 | -0.5914 | Yes |
| 75 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 35106 | -1.567 | -0.5780 | Yes |
| 76 | ACAD10 | acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597] | 35152 | -1.589 | -0.5653 | Yes |
| 77 | ACAT2 | acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94] | 35246 | -1.644 | -0.5533 | Yes |
| 78 | PCCA | propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653] | 35247 | -1.644 | -0.5389 | Yes |
| 79 | ACACB | acetyl-CoA carboxylase beta [Source:HGNC Symbol;Acc:HGNC:85] | 35315 | -1.679 | -0.5260 | Yes |
| 80 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 35456 | -1.752 | -0.5143 | Yes |
| 81 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 35495 | -1.773 | -0.4998 | Yes |
| 82 | LPIN3 | lipin 3 [Source:HGNC Symbol;Acc:HGNC:14451] | 35536 | -1.800 | -0.4851 | Yes |
| 83 | ABCD4 | ATP binding cassette subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:68] | 35538 | -1.802 | -0.4693 | Yes |
| 84 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 35589 | -1.831 | -0.4545 | Yes |
| 85 | MMUT | methylmalonyl-CoA mutase [Source:HGNC Symbol;Acc:HGNC:7526] | 35642 | -1.869 | -0.4395 | Yes |
| 86 | LPIN1 | lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] | 35648 | -1.872 | -0.4232 | Yes |
| 87 | ACADM | acyl-CoA dehydrogenase medium chain [Source:HGNC Symbol;Acc:HGNC:89] | 35661 | -1.880 | -0.4070 | Yes |
| 88 | PLA2G15 | phospholipase A2 group XV [Source:HGNC Symbol;Acc:HGNC:17163] | 35719 | -1.918 | -0.3917 | Yes |
| 89 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 35756 | -1.942 | -0.3756 | Yes |
| 90 | MCEE | methylmalonyl-CoA epimerase [Source:HGNC Symbol;Acc:HGNC:16732] | 35959 | -2.094 | -0.3627 | Yes |
| 91 | ACADS | acyl-CoA dehydrogenase short chain [Source:HGNC Symbol;Acc:HGNC:90] | 35964 | -2.101 | -0.3443 | Yes |
| 92 | GCDH | glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189] | 36103 | -2.226 | -0.3285 | Yes |
| 93 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 36117 | -2.237 | -0.3092 | Yes |
| 94 | HSD17B10 | hydroxysteroid 17-beta dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:4800] | 36216 | -2.330 | -0.2913 | Yes |
| 95 | AUH | AU RNA binding methylglutaconyl-CoA hydratase [Source:HGNC Symbol;Acc:HGNC:890] | 36248 | -2.358 | -0.2715 | Yes |
| 96 | FAAH | fatty acid amide hydrolase [Source:HGNC Symbol;Acc:HGNC:3553] | 36315 | -2.425 | -0.2519 | Yes |
| 97 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 36378 | -2.484 | -0.2318 | Yes |
| 98 | ACAA2 | acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83] | 36522 | -2.683 | -0.2121 | Yes |
| 99 | CROT | carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366] | 36602 | -2.781 | -0.1898 | Yes |
| 100 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 36661 | -2.866 | -0.1662 | Yes |
| 101 | HACL1 | 2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856] | 36706 | -2.963 | -0.1413 | Yes |
| 102 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36718 | -2.985 | -0.1154 | Yes |
| 103 | ETFBKMT | electron transfer flavoprotein subunit beta lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:28739] | 36751 | -3.059 | -0.0894 | Yes |
| 104 | HADH | hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799] | 36786 | -3.143 | -0.0627 | Yes |
| 105 | CPT1A | carnitine palmitoyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:2328] | 36893 | -3.439 | -0.0353 | Yes |
| 106 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37080 | -4.623 | 0.0003 | Yes |
