Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GOCC_PRERIBOSOME |
| Enrichment Score (ES) | 0.7886223 |
| Normalized Enrichment Score (NES) | 1.9265901 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0050132237 |
| FWER p-Value | 0.016 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TSR1 | TSR1 ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25542] | 279 | 2.593 | 0.0265 | Yes |
| 2 | RIOK3 | RIO kinase 3 [Source:HGNC Symbol;Acc:HGNC:11451] | 362 | 2.364 | 0.0552 | Yes |
| 3 | FP565260.1 | periodic tryptophan protein 2 homolog [Source:NCBI gene (formerly Entrezgene);Acc:102724159] | 433 | 2.191 | 0.0820 | Yes |
| 4 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 457 | 2.138 | 0.1094 | Yes |
| 5 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 466 | 2.111 | 0.1369 | Yes |
| 6 | RIOK2 | RIO kinase 2 [Source:HGNC Symbol;Acc:HGNC:18999] | 479 | 2.084 | 0.1639 | Yes |
| 7 | UTP4 | UTP4 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:1983] | 518 | 2.018 | 0.1893 | Yes |
| 8 | MDN1 | midasin AAA ATPase 1 [Source:HGNC Symbol;Acc:HGNC:18302] | 539 | 1.987 | 0.2148 | Yes |
| 9 | UTP25 | UTP25 small subunit processor component [Source:HGNC Symbol;Acc:HGNC:28440] | 556 | 1.956 | 0.2400 | Yes |
| 10 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 575 | 1.922 | 0.2647 | Yes |
| 11 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 598 | 1.878 | 0.2887 | Yes |
| 12 | NOP58 | NOP58 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:29926] | 607 | 1.865 | 0.3129 | Yes |
| 13 | NOL10 | nucleolar protein 10 [Source:HGNC Symbol;Acc:HGNC:25862] | 762 | 1.635 | 0.3302 | Yes |
| 14 | EIF6 | eukaryotic translation initiation factor 6 [Source:HGNC Symbol;Acc:HGNC:6159] | 927 | 1.477 | 0.3451 | Yes |
| 15 | PDCD11 | programmed cell death 11 [Source:HGNC Symbol;Acc:HGNC:13408] | 940 | 1.462 | 0.3640 | Yes |
| 16 | UTP23 | UTP23 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:28224] | 974 | 1.438 | 0.3819 | Yes |
| 17 | BMS1 | BMS1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:23505] | 989 | 1.422 | 0.4002 | Yes |
| 18 | WDR46 | WD repeat domain 46 [Source:HGNC Symbol;Acc:HGNC:13923] | 1031 | 1.390 | 0.4173 | Yes |
| 19 | WDR37 | WD repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:31406] | 1048 | 1.375 | 0.4349 | Yes |
| 20 | HEATR1 | HEAT repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:25517] | 1082 | 1.344 | 0.4516 | Yes |
| 21 | WDR12 | WD repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:14098] | 1109 | 1.324 | 0.4683 | Yes |
| 22 | EBNA1BP2 | EBNA1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15531] | 1117 | 1.317 | 0.4853 | Yes |
| 23 | PWP2 | PWP2 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:9711] | 1120 | 1.314 | 0.5025 | Yes |
| 24 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 1126 | 1.312 | 0.5196 | Yes |
| 25 | RSL1D1 | ribosomal L1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24534] | 1130 | 1.311 | 0.5367 | Yes |
| 26 | FTSJ3 | FtsJ RNA 2'-O-methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:17136] | 1137 | 1.303 | 0.5536 | Yes |
| 27 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 1138 | 1.302 | 0.5706 | Yes |
| 28 | NOL6 | nucleolar protein 6 [Source:HGNC Symbol;Acc:HGNC:19910] | 1173 | 1.281 | 0.5865 | Yes |
| 29 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 1236 | 1.233 | 0.6010 | Yes |
| 30 | LTV1 | LTV1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:21173] | 1251 | 1.222 | 0.6166 | Yes |
| 31 | SNU13 | small nuclear ribonucleoprotein 13 [Source:HGNC Symbol;Acc:HGNC:7819] | 1267 | 1.217 | 0.6322 | Yes |
| 32 | RRP7BP | ribosomal RNA processing 7 homolog B, pseudogene [Source:HGNC Symbol;Acc:HGNC:30454] | 1296 | 1.204 | 0.6472 | Yes |
| 33 | RRS1 | ribosome biogenesis regulator 1 homolog [Source:HGNC Symbol;Acc:HGNC:17083] | 1373 | 1.170 | 0.6605 | Yes |
| 34 | NOP14 | NOP14 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:16821] | 1391 | 1.160 | 0.6752 | Yes |
| 35 | BOP1 | BOP1 ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:15519] | 1548 | 1.089 | 0.6853 | Yes |
| 36 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 1649 | 1.039 | 0.6962 | Yes |
| 37 | SRFBP1 | serum response factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26333] | 1769 | 0.977 | 0.7058 | Yes |
| 38 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 1979 | 0.900 | 0.7119 | Yes |
| 39 | MAK16 | MAK16 homolog [Source:HGNC Symbol;Acc:HGNC:13703] | 2162 | 0.832 | 0.7179 | Yes |
| 40 | UTP6 | UTP6 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:18279] | 2227 | 0.808 | 0.7268 | Yes |
| 41 | EMG1 | EMG1 N1-specific pseudouridine methyltransferase [Source:HGNC Symbol;Acc:HGNC:16912] | 2260 | 0.797 | 0.7364 | Yes |
| 42 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 2471 | 0.731 | 0.7403 | Yes |
| 43 | TBL3 | transducin beta like 3 [Source:HGNC Symbol;Acc:HGNC:11587] | 2602 | 0.690 | 0.7458 | Yes |
| 44 | RPF1 | ribosome production factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:30350] | 2853 | 0.629 | 0.7473 | Yes |
| 45 | DCAF13 | DDB1 and CUL4 associated factor 13 [Source:HGNC Symbol;Acc:HGNC:24535] | 2920 | 0.609 | 0.7535 | Yes |
| 46 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 3028 | 0.584 | 0.7582 | Yes |
| 47 | FBL | fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599] | 3080 | 0.576 | 0.7644 | Yes |
| 48 | RIOK1 | RIO kinase 1 [Source:HGNC Symbol;Acc:HGNC:18656] | 3219 | 0.547 | 0.7678 | Yes |
| 49 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 3282 | 0.533 | 0.7731 | Yes |
| 50 | RRP1B | ribosomal RNA processing 1B [Source:HGNC Symbol;Acc:HGNC:23818] | 3643 | 0.465 | 0.7695 | Yes |
| 51 | KRR1 | KRR1 small subunit processome component homolog [Source:HGNC Symbol;Acc:HGNC:5176] | 3767 | 0.444 | 0.7720 | Yes |
| 52 | XRCC5 | X-ray repair cross complementing 5 [Source:HGNC Symbol;Acc:HGNC:12833] | 3847 | 0.428 | 0.7755 | Yes |
| 53 | WDR36 | WD repeat domain 36 [Source:HGNC Symbol;Acc:HGNC:30696] | 4026 | 0.392 | 0.7758 | Yes |
| 54 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 4071 | 0.385 | 0.7797 | Yes |
| 55 | FCF1 | FCF1 rRNA-processing protein [Source:HGNC Symbol;Acc:HGNC:20220] | 4320 | 0.342 | 0.7774 | Yes |
| 56 | UTP14C | UTP14C small subunit processome component [Source:HGNC Symbol;Acc:HGNC:20321] | 4347 | 0.338 | 0.7812 | Yes |
| 57 | WDR3 | WD repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:12755] | 4349 | 0.337 | 0.7856 | Yes |
| 58 | RRP7A | ribosomal RNA processing 7 homolog A [Source:HGNC Symbol;Acc:HGNC:24286] | 4424 | 0.324 | 0.7878 | Yes |
| 59 | KRI1 | KRI1 homolog [Source:HGNC Symbol;Acc:HGNC:25769] | 4543 | 0.305 | 0.7886 | Yes |
| 60 | UTP18 | UTP18 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24274] | 4707 | 0.278 | 0.7879 | No |
| 61 | NGDN | neuroguidin [Source:HGNC Symbol;Acc:HGNC:20271] | 5335 | 0.183 | 0.7733 | No |
| 62 | UTP14A | UTP14A small subunit processome component [Source:HGNC Symbol;Acc:HGNC:10665] | 5430 | 0.170 | 0.7730 | No |
| 63 | UTP11 | UTP11 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24329] | 5594 | 0.147 | 0.7705 | No |
| 64 | FBLL1 | fibrillarin like 1 [Source:HGNC Symbol;Acc:HGNC:35458] | 6102 | 0.080 | 0.7579 | No |
| 65 | NOP9 | NOP9 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:19826] | 6622 | 0.010 | 0.7440 | No |
| 66 | NOC2L | NOC2 like nucleolar associated transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:24517] | 27541 | -0.003 | 0.1789 | No |
| 67 | RRP36 | ribosomal RNA processing 36 [Source:HGNC Symbol;Acc:HGNC:21374] | 28170 | -0.080 | 0.1630 | No |
| 68 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 29035 | -0.185 | 0.1421 | No |
| 69 | RPS7 | ribosomal protein S7 [Source:HGNC Symbol;Acc:HGNC:10440] | 29305 | -0.218 | 0.1376 | No |
| 70 | NOB1 | NIN1 (RPN12) binding protein 1 homolog [Source:HGNC Symbol;Acc:HGNC:29540] | 29783 | -0.279 | 0.1284 | No |
| 71 | ZNF622 | zinc finger protein 622 [Source:HGNC Symbol;Acc:HGNC:30958] | 30469 | -0.363 | 0.1146 | No |
| 72 | RRP1 | ribosomal RNA processing 1 [Source:HGNC Symbol;Acc:HGNC:18785] | 31135 | -0.459 | 0.1027 | No |
| 73 | NSA2 | NSA2 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:30728] | 31160 | -0.463 | 0.1081 | No |
| 74 | FAM207A | family with sequence similarity 207 member A [Source:HGNC Symbol;Acc:HGNC:15811] | 31530 | -0.527 | 0.1050 | No |
| 75 | UTP3 | UTP3 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24477] | 31939 | -0.596 | 0.1018 | No |
| 76 | IMP3 | IMP U3 small nucleolar ribonucleoprotein 3 [Source:HGNC Symbol;Acc:HGNC:14497] | 32856 | -0.798 | 0.0876 | No |
| 77 | FBXW9 | F-box and WD repeat domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28136] | 33344 | -0.925 | 0.0865 | No |
| 78 | PRKDC | protein kinase, DNA-activated, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9413] | 33969 | -1.119 | 0.0843 | No |
