Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GOCC_T_CELL_RECEPTOR_COMPLEX |
| Enrichment Score (ES) | 0.7135595 |
| Normalized Enrichment Score (NES) | 1.8769356 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.014711301 |
| FWER p-Value | 0.069 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | APBB1IP | amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379] | 448 | 2.146 | 0.2876 | Yes |
| 2 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 803 | 1.594 | 0.5006 | Yes |
| 3 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 866 | 1.537 | 0.7136 | Yes |
| 4 | CD247 | CD247 molecule [Source:HGNC Symbol;Acc:HGNC:1677] | 8411 | 0.000 | 0.5095 | No |
| 5 | TRAV29DV5 | T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12127] | 8663 | 0.000 | 0.5027 | No |
| 6 | TRAV12-3 | T cell receptor alpha variable 12-3 [Source:HGNC Symbol;Acc:HGNC:12107] | 8950 | 0.000 | 0.4950 | No |
| 7 | TRAV12-2 | T cell receptor alpha variable 12-2 [Source:HGNC Symbol;Acc:HGNC:12106] | 8951 | 0.000 | 0.4950 | No |
| 8 | TRAV12-1 | T cell receptor alpha variable 12-1 [Source:HGNC Symbol;Acc:HGNC:12105] | 8952 | 0.000 | 0.4950 | No |
| 9 | TRAV38-1 | T cell receptor alpha variable 38-1 [Source:HGNC Symbol;Acc:HGNC:12137] | 9026 | 0.000 | 0.4930 | No |
| 10 | TRAV13-2 | T cell receptor alpha variable 13-2 [Source:HGNC Symbol;Acc:HGNC:12109] | 9388 | 0.000 | 0.4832 | No |
| 11 | TRAV13-1 | T cell receptor alpha variable 13-1 [Source:HGNC Symbol;Acc:HGNC:12108] | 9389 | 0.000 | 0.4832 | No |
| 12 | TRAV41 | T cell receptor alpha variable 41 [Source:HGNC Symbol;Acc:HGNC:12142] | 9638 | 0.000 | 0.4765 | No |
| 13 | TRAV40 | T cell receptor alpha variable 40 [Source:HGNC Symbol;Acc:HGNC:12141] | 9639 | 0.000 | 0.4765 | No |
| 14 | TRAV39 | T cell receptor alpha variable 39 [Source:HGNC Symbol;Acc:HGNC:12139] | 9642 | 0.000 | 0.4765 | No |
| 15 | TRAV30 | T cell receptor alpha variable 30 [Source:HGNC Symbol;Acc:HGNC:12129] | 9648 | 0.000 | 0.4763 | No |
| 16 | TRAV35 | T cell receptor alpha variable 35 [Source:HGNC Symbol;Acc:HGNC:12134] | 9651 | 0.000 | 0.4763 | No |
| 17 | TRAV34 | T cell receptor alpha variable 34 [Source:HGNC Symbol;Acc:HGNC:12133] | 9652 | 0.000 | 0.4763 | No |
| 18 | TRAV27 | T cell receptor alpha variable 27 [Source:HGNC Symbol;Acc:HGNC:12125] | 9659 | 0.000 | 0.4761 | No |
| 19 | TRAV20 | T cell receptor alpha variable 20 [Source:HGNC Symbol;Acc:HGNC:12117] | 9660 | 0.000 | 0.4761 | No |
| 20 | TRAV22 | T cell receptor alpha variable 22 [Source:HGNC Symbol;Acc:HGNC:12119] | 9661 | 0.000 | 0.4761 | No |
| 21 | TRBV25-1 | T cell receptor beta variable 25-1 [Source:HGNC Symbol;Acc:HGNC:12205] | 10306 | 0.000 | 0.4587 | No |
| 22 | TRBV24-1 | T cell receptor beta variable 24-1 [Source:HGNC Symbol;Acc:HGNC:12203] | 10618 | 0.000 | 0.4503 | No |
| 23 | TRBV23-1 | T cell receptor beta variable 23-1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12201] | 10889 | 0.000 | 0.4430 | No |
| 24 | TRBV20-1 | T cell receptor beta variable 20-1 [Source:HGNC Symbol;Acc:HGNC:12196] | 11850 | 0.000 | 0.4170 | No |
| 25 | TRAV23DV6 | T cell receptor alpha variable 23/delta variable 6 [Source:HGNC Symbol;Acc:HGNC:12120] | 11897 | 0.000 | 0.4158 | No |
| 26 | TRBJ2-6 | T cell receptor beta joining 2-6 [Source:HGNC Symbol;Acc:HGNC:12174] | 12498 | 0.000 | 0.3995 | No |
| 27 | TRBJ2-5 | T cell receptor beta joining 2-5 [Source:HGNC Symbol;Acc:HGNC:12173] | 12499 | 0.000 | 0.3995 | No |
| 28 | TRBJ2-7 | T cell receptor beta joining 2-7 [Source:HGNC Symbol;Acc:HGNC:12175] | 12501 | 0.000 | 0.3995 | No |
| 29 | TRBJ2-2 | T cell receptor beta joining 2-2 [Source:HGNC Symbol;Acc:HGNC:12169] | 12502 | 0.000 | 0.3995 | No |
| 30 | TRBJ2-1 | T cell receptor beta joining 2-1 [Source:HGNC Symbol;Acc:HGNC:12168] | 12504 | 0.000 | 0.3995 | No |
| 31 | TRBJ2-4 | T cell receptor beta joining 2-4 [Source:HGNC Symbol;Acc:HGNC:12172] | 12505 | 0.000 | 0.3995 | No |
| 32 | TRBJ2-3 | T cell receptor beta joining 2-3 [Source:HGNC Symbol;Acc:HGNC:12171] | 12506 | 0.000 | 0.3995 | No |
| 33 | TRAV1-1 | T cell receptor alpha variable 1-1 [Source:HGNC Symbol;Acc:HGNC:12101] | 13301 | 0.000 | 0.3780 | No |
| 34 | TRAV1-2 | T cell receptor alpha variable 1-2 [Source:HGNC Symbol;Acc:HGNC:12102] | 13302 | 0.000 | 0.3780 | No |
| 35 | TRAV8-4 | T cell receptor alpha variable 8-4 [Source:HGNC Symbol;Acc:HGNC:12149] | 13764 | 0.000 | 0.3655 | No |
| 36 | TRAV8-6 | T cell receptor alpha variable 8-6 [Source:HGNC Symbol;Acc:HGNC:12151] | 13766 | 0.000 | 0.3655 | No |
| 37 | TRAV8-1 | T cell receptor alpha variable 8-1 [Source:HGNC Symbol;Acc:HGNC:12146] | 13769 | 0.000 | 0.3654 | No |
| 38 | TRAV8-2 | T cell receptor alpha variable 8-2 [Source:HGNC Symbol;Acc:HGNC:12147] | 13770 | 0.000 | 0.3654 | No |
| 39 | TRAV8-3 | T cell receptor alpha variable 8-3 [Source:HGNC Symbol;Acc:HGNC:12148] | 13771 | 0.000 | 0.3654 | No |
| 40 | TRAV9-1 | T cell receptor alpha variable 9-1 [Source:HGNC Symbol;Acc:HGNC:12153] | 14159 | 0.000 | 0.3550 | No |
| 41 | TRAV9-2 | T cell receptor alpha variable 9-2 [Source:HGNC Symbol;Acc:HGNC:12154] | 14160 | 0.000 | 0.3550 | No |
| 42 | TRAV26-1 | T cell receptor alpha variable 26-1 [Source:HGNC Symbol;Acc:HGNC:12123] | 15328 | 0.000 | 0.3234 | No |
| 43 | TRAV26-2 | T cell receptor alpha variable 26-2 [Source:HGNC Symbol;Acc:HGNC:12124] | 15329 | 0.000 | 0.3234 | No |
| 44 | TRDD1 | T cell receptor delta diversity 1 [Source:HGNC Symbol;Acc:HGNC:12254] | 15669 | 0.000 | 0.3142 | No |
| 45 | TRDJ1 | T cell receptor delta joining 1 [Source:HGNC Symbol;Acc:HGNC:12257] | 15733 | 0.000 | 0.3125 | No |
| 46 | TRDV2 | T cell receptor delta variable 2 [Source:HGNC Symbol;Acc:HGNC:12263] | 15770 | 0.000 | 0.3116 | No |
| 47 | TRDV3 | T cell receptor delta variable 3 [Source:HGNC Symbol;Acc:HGNC:12264] | 15773 | 0.000 | 0.3115 | No |
| 48 | TRDV1 | T cell receptor delta variable 1 [Source:HGNC Symbol;Acc:HGNC:12262] | 15776 | 0.000 | 0.3114 | No |
| 49 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15859 | 0.000 | 0.3092 | No |
| 50 | CD6 | CD6 molecule [Source:HGNC Symbol;Acc:HGNC:1691] | 15860 | 0.000 | 0.3092 | No |
| 51 | ZAP70 | zeta chain of T cell receptor associated protein kinase 70 [Source:HGNC Symbol;Acc:HGNC:12858] | 16121 | 0.000 | 0.3022 | No |
| 52 | TRBV11-1 | T cell receptor beta variable 11-1 [Source:HGNC Symbol;Acc:HGNC:12180] | 16372 | 0.000 | 0.2954 | No |
| 53 | TRBV11-2 | T cell receptor beta variable 11-2 [Source:HGNC Symbol;Acc:HGNC:12181] | 16373 | 0.000 | 0.2954 | No |
| 54 | TRGC2 | T cell receptor gamma constant 2 [Source:HGNC Symbol;Acc:HGNC:12276] | 16389 | 0.000 | 0.2950 | No |
| 55 | TRBV10-1 | T cell receptor beta variable 10-1(gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12177] | 16740 | 0.000 | 0.2856 | No |
| 56 | TRBV10-2 | T cell receptor beta variable 10-2 [Source:HGNC Symbol;Acc:HGNC:12178] | 16741 | 0.000 | 0.2856 | No |
| 57 | TRAV36DV7 | T cell receptor alpha variable 36/delta variable 7 [Source:HGNC Symbol;Acc:HGNC:12135] | 16896 | 0.000 | 0.2814 | No |
| 58 | TRGJ2 | T cell receptor gamma joining 2 [Source:HGNC Symbol;Acc:HGNC:12278] | 17202 | 0.000 | 0.2731 | No |
| 59 | TRGV3 | T cell receptor gamma variable 3 [Source:HGNC Symbol;Acc:HGNC:12288] | 17225 | 0.000 | 0.2725 | No |
| 60 | TRGV4 | T cell receptor gamma variable 4 [Source:HGNC Symbol;Acc:HGNC:12289] | 17226 | 0.000 | 0.2725 | No |
| 61 | TRGV1 | T cell receptor gamma variable 1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12284] | 17227 | 0.000 | 0.2725 | No |
| 62 | TRGV2 | T cell receptor gamma variable 2 [Source:HGNC Symbol;Acc:HGNC:12287] | 17228 | 0.000 | 0.2725 | No |
| 63 | TRGV9 | T cell receptor gamma variable 9 [Source:HGNC Symbol;Acc:HGNC:12295] | 17229 | 0.000 | 0.2725 | No |
| 64 | TRGV8 | T cell receptor gamma variable 8 [Source:HGNC Symbol;Acc:HGNC:12294] | 17232 | 0.000 | 0.2725 | No |
| 65 | TRGV5 | T cell receptor gamma variable 5 [Source:HGNC Symbol;Acc:HGNC:12290] | 17233 | 0.000 | 0.2725 | No |
| 66 | TRBV6-4 | T cell receptor beta variable 6-4 [Source:HGNC Symbol;Acc:HGNC:12229] | 18098 | 0.000 | 0.2491 | No |
| 67 | TRBV6-1 | T cell receptor beta variable 6-1 [Source:HGNC Symbol;Acc:HGNC:12226] | 18099 | 0.000 | 0.2491 | No |
| 68 | TRBV6-7 | T cell receptor beta variable 6-7 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12232] | 18100 | 0.000 | 0.2491 | No |
| 69 | TRBV6-8 | T cell receptor beta variable 6-8 [Source:HGNC Symbol;Acc:HGNC:12233] | 18101 | 0.000 | 0.2491 | No |
| 70 | TRBV6-5 | T cell receptor beta variable 6-5 [Source:HGNC Symbol;Acc:HGNC:12230] | 18103 | 0.000 | 0.2491 | No |
| 71 | TRBV6-6 | T cell receptor beta variable 6-6 [Source:HGNC Symbol;Acc:HGNC:12231] | 18104 | 0.000 | 0.2491 | No |
| 72 | TRBV5-1 | T cell receptor beta variable 5-1 [Source:HGNC Symbol;Acc:HGNC:12218] | 18323 | 0.000 | 0.2432 | No |
| 73 | TRBV5-4 | T cell receptor beta variable 5-4 [Source:HGNC Symbol;Acc:HGNC:12221] | 18324 | 0.000 | 0.2432 | No |
| 74 | TRBV5-5 | T cell receptor beta variable 5-5 [Source:HGNC Symbol;Acc:HGNC:12222] | 18325 | 0.000 | 0.2432 | No |
| 75 | TRBV5-3 | T cell receptor beta variable 5-3 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12220] | 18327 | 0.000 | 0.2432 | No |
| 76 | TRBV5-6 | T cell receptor beta variable 5-6 [Source:HGNC Symbol;Acc:HGNC:12223] | 18328 | 0.000 | 0.2432 | No |
| 77 | TRBV5-7 | T cell receptor beta variable 5-7 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12224] | 18330 | 0.000 | 0.2431 | No |
| 78 | TRBV7-3 | T cell receptor beta variable 7-3 [Source:HGNC Symbol;Acc:HGNC:12237] | 18428 | 0.000 | 0.2405 | No |
| 79 | TRBV7-1 | T cell receptor beta variable 7-1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12235] | 18429 | 0.000 | 0.2405 | No |
| 80 | TRBV7-6 | T cell receptor beta variable 7-6 [Source:HGNC Symbol;Acc:HGNC:12240] | 18430 | 0.000 | 0.2405 | No |
| 81 | TRBV7-7 | T cell receptor beta variable 7-7 [Source:HGNC Symbol;Acc:HGNC:12241] | 18431 | 0.000 | 0.2405 | No |
| 82 | TRBV7-4 | T cell receptor beta variable 7-4 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12238] | 18432 | 0.000 | 0.2405 | No |
| 83 | TRBV3-1 | T cell receptor beta variable 3-1 [Source:HGNC Symbol;Acc:HGNC:12212] | 19112 | 0.000 | 0.2221 | No |
| 84 | TRBV4-1 | T cell receptor beta variable 4-1 [Source:HGNC Symbol;Acc:HGNC:12215] | 19352 | 0.000 | 0.2157 | No |
| 85 | TRBV4-2 | T cell receptor beta variable 4-2 [Source:HGNC Symbol;Acc:HGNC:12216] | 19354 | 0.000 | 0.2157 | No |
| 86 | TRAV14DV4 | T cell receptor alpha variable 14/delta variable 4 [Source:HGNC Symbol;Acc:HGNC:12110] | 20220 | 0.000 | 0.1923 | No |
| 87 | TRAC | T cell receptor alpha constant [Source:HGNC Symbol;Acc:HGNC:12029] | 21602 | 0.000 | 0.1549 | No |
| 88 | TRDC | T cell receptor delta constant [Source:HGNC Symbol;Acc:HGNC:12253] | 21635 | 0.000 | 0.1540 | No |
| 89 | TRBV29-1 | T cell receptor beta variable 29-1 [Source:HGNC Symbol;Acc:HGNC:12210] | 22552 | 0.000 | 0.1293 | No |
| 90 | TRBV30 | T cell receptor beta variable 30 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12214] | 22686 | 0.000 | 0.1257 | No |
| 91 | TRBV28 | T cell receptor beta variable 28 [Source:HGNC Symbol;Acc:HGNC:12209] | 22688 | 0.000 | 0.1256 | No |
| 92 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 22694 | 0.000 | 0.1255 | No |
| 93 | TRBV19 | T cell receptor beta variable 19 [Source:HGNC Symbol;Acc:HGNC:12194] | 22700 | 0.000 | 0.1254 | No |
| 94 | CD3G | CD3g molecule [Source:HGNC Symbol;Acc:HGNC:1675] | 23019 | 0.000 | 0.1168 | No |
| 95 | CD3E | CD3e molecule [Source:HGNC Symbol;Acc:HGNC:1674] | 23022 | 0.000 | 0.1167 | No |
| 96 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 23023 | 0.000 | 0.1167 | No |
| 97 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 23116 | 0.000 | 0.1142 | No |
| 98 | CD8A | CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706] | 23117 | 0.000 | 0.1142 | No |
| 99 | TRAV38-2DV8 | T cell receptor alpha variable 38-2/delta variable 8 [Source:HGNC Symbol;Acc:HGNC:12138] | 23913 | 0.000 | 0.0927 | No |
| 100 | SKAP1 | src kinase associated phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15605] | 24064 | 0.000 | 0.0887 | No |
| 101 | TRGV10 | T cell receptor gamma variable 10 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12285] | 24977 | 0.000 | 0.0640 | No |
| 102 | TRGV11 | T cell receptor gamma variable 11 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12286] | 24979 | 0.000 | 0.0640 | No |
| 103 | TRAV21 | T cell receptor alpha variable 21 [Source:HGNC Symbol;Acc:HGNC:12118] | 25284 | 0.000 | 0.0557 | No |
| 104 | TRAV24 | T cell receptor alpha variable 24 [Source:HGNC Symbol;Acc:HGNC:12121] | 25285 | 0.000 | 0.0557 | No |
| 105 | TRAV25 | T cell receptor alpha variable 25 [Source:HGNC Symbol;Acc:HGNC:12122] | 25287 | 0.000 | 0.0557 | No |
| 106 | TRAV17 | T cell receptor alpha variable 17 [Source:HGNC Symbol;Acc:HGNC:12113] | 25292 | 0.000 | 0.0556 | No |
| 107 | TRAV16 | T cell receptor alpha variable 16 [Source:HGNC Symbol;Acc:HGNC:12112] | 25293 | 0.000 | 0.0556 | No |
| 108 | TRAV19 | T cell receptor alpha variable 19 [Source:HGNC Symbol;Acc:HGNC:12115] | 25294 | 0.000 | 0.0556 | No |
| 109 | TRAV18 | T cell receptor alpha variable 18 [Source:HGNC Symbol;Acc:HGNC:12114] | 25295 | 0.000 | 0.0556 | No |
| 110 | TRAV10 | T cell receptor alpha variable 10 [Source:HGNC Symbol;Acc:HGNC:12103] | 25301 | 0.000 | 0.0555 | No |
| 111 | TRBC2 | T cell receptor beta constant 2 [Source:HGNC Symbol;Acc:HGNC:12157] | 26829 | 0.000 | 0.0142 | No |
| 112 | TRBV9 | T cell receptor beta variable 9 [Source:HGNC Symbol;Acc:HGNC:12246] | 27100 | 0.000 | 0.0068 | No |
| 113 | TRBV2 | T cell receptor beta variable 2 [Source:HGNC Symbol;Acc:HGNC:12195] | 27101 | 0.000 | 0.0068 | No |
| 114 | TRAJ3 | T cell receptor alpha joining 3 [Source:HGNC Symbol;Acc:HGNC:12059] | 27207 | 0.000 | 0.0040 | No |
| 115 | TRAV2 | T cell receptor alpha variable 2 [Source:HGNC Symbol;Acc:HGNC:12116] | 27484 | 0.000 | -0.0035 | No |
| 116 | TRAV7 | T cell receptor alpha variable 7 [Source:HGNC Symbol;Acc:HGNC:12145] | 27486 | 0.000 | -0.0035 | No |
| 117 | TRAV4 | T cell receptor alpha variable 4 [Source:HGNC Symbol;Acc:HGNC:12140] | 27489 | 0.000 | -0.0035 | No |
| 118 | TRAV3 | T cell receptor alpha variable 3 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12128] | 27491 | 0.000 | -0.0036 | No |
| 119 | TRAV6 | T cell receptor alpha variable 6 [Source:HGNC Symbol;Acc:HGNC:12144] | 27492 | 0.000 | -0.0036 | No |
| 120 | TRAV5 | T cell receptor alpha variable 5 [Source:HGNC Symbol;Acc:HGNC:12143] | 27494 | 0.000 | -0.0036 | No |
| 121 | TRAT1 | T cell receptor associated transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:30698] | 27501 | 0.000 | -0.0038 | No |
| 122 | STOML2 | stomatin like 2 [Source:HGNC Symbol;Acc:HGNC:14559] | 31464 | -0.515 | -0.0389 | No |
| 123 | PTPN6 | protein tyrosine phosphatase non-receptor type 6 [Source:HGNC Symbol;Acc:HGNC:9658] | 32090 | -0.629 | 0.0321 | No |
| 124 | CEACAM1 | CEA cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:1814] | 32621 | -0.739 | 0.1209 | No |
