Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GOMF_CHEMOKINE_RECEPTOR_BINDING |
| Enrichment Score (ES) | 0.83365124 |
| Normalized Enrichment Score (NES) | 2.0193188 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0024866008 |
| FWER p-Value | 0.002 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 6 | 4.903 | 0.2369 | Yes |
| 2 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 13 | 4.731 | 0.4656 | Yes |
| 3 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 220 | 2.811 | 0.5959 | Yes |
| 4 | NARS1 | asparaginyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7643] | 944 | 1.459 | 0.6469 | Yes |
| 5 | CNIH4 | cornichon family AMPA receptor auxiliary protein 4 [Source:HGNC Symbol;Acc:HGNC:25013] | 1625 | 1.051 | 0.6794 | Yes |
| 6 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 2056 | 0.871 | 0.7099 | Yes |
| 7 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 2084 | 0.861 | 0.7508 | Yes |
| 8 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2775 | 0.646 | 0.7634 | Yes |
| 9 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 3024 | 0.584 | 0.7849 | Yes |
| 10 | CKLF | chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253] | 3386 | 0.510 | 0.7998 | Yes |
| 11 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 4411 | 0.326 | 0.7879 | Yes |
| 12 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 4486 | 0.315 | 0.8012 | Yes |
| 13 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 4513 | 0.310 | 0.8155 | Yes |
| 14 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4624 | 0.294 | 0.8267 | Yes |
| 15 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 4831 | 0.259 | 0.8337 | Yes |
| 16 | YARS1 | tyrosyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12840] | 5931 | 0.103 | 0.8090 | No |
| 17 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 6078 | 0.083 | 0.8091 | No |
| 18 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6710 | 0.000 | 0.7920 | No |
| 19 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6711 | 0.000 | 0.7920 | No |
| 20 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6712 | 0.000 | 0.7920 | No |
| 21 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6731 | 0.000 | 0.7915 | No |
| 22 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6732 | 0.000 | 0.7915 | No |
| 23 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6734 | 0.000 | 0.7915 | No |
| 24 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6735 | 0.000 | 0.7915 | No |
| 25 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6737 | 0.000 | 0.7915 | No |
| 26 | CCL25 | C-C motif chemokine ligand 25 [Source:HGNC Symbol;Acc:HGNC:10624] | 6738 | 0.000 | 0.7915 | No |
| 27 | CCL24 | C-C motif chemokine ligand 24 [Source:HGNC Symbol;Acc:HGNC:10623] | 6739 | 0.000 | 0.7915 | No |
| 28 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6741 | 0.000 | 0.7914 | No |
| 29 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6742 | 0.000 | 0.7914 | No |
| 30 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6743 | 0.000 | 0.7914 | No |
| 31 | CCL28 | C-C motif chemokine ligand 28 [Source:HGNC Symbol;Acc:HGNC:17700] | 6761 | 0.000 | 0.7910 | No |
| 32 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6763 | 0.000 | 0.7910 | No |
| 33 | CCL26 | C-C motif chemokine ligand 26 [Source:HGNC Symbol;Acc:HGNC:10625] | 6765 | 0.000 | 0.7909 | No |
| 34 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 7504 | 0.000 | 0.7710 | No |
| 35 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 9023 | 0.000 | 0.7300 | No |
| 36 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10991 | 0.000 | 0.6769 | No |
| 37 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11212 | 0.000 | 0.6709 | No |
| 38 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11369 | 0.000 | 0.6667 | No |
| 39 | MSMP | microseminoprotein, prostate associated [Source:HGNC Symbol;Acc:HGNC:29663] | 12631 | 0.000 | 0.6326 | No |
| 40 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14914 | 0.000 | 0.5710 | No |
| 41 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14915 | 0.000 | 0.5710 | No |
| 42 | XCL2 | X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10646] | 15963 | 0.000 | 0.5427 | No |
| 43 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15965 | 0.000 | 0.5427 | No |
| 44 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16191 | 0.000 | 0.5366 | No |
| 45 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18871 | 0.000 | 0.4643 | No |
| 46 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18906 | 0.000 | 0.4633 | No |
| 47 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18907 | 0.000 | 0.4633 | No |
| 48 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19419 | 0.000 | 0.4495 | No |
| 49 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19421 | 0.000 | 0.4495 | No |
| 50 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19424 | 0.000 | 0.4495 | No |
| 51 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19433 | 0.000 | 0.4492 | No |
| 52 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 19965 | 0.000 | 0.4349 | No |
| 53 | TFF2 | trefoil factor 2 [Source:HGNC Symbol;Acc:HGNC:11756] | 20667 | 0.000 | 0.4160 | No |
| 54 | DEFB109B | defensin beta 109B [Source:HGNC Symbol;Acc:HGNC:33469] | 20981 | 0.000 | 0.4075 | No |
| 55 | DEFB130A | defensin beta 130A [Source:HGNC Symbol;Acc:HGNC:18107] | 22028 | 0.000 | 0.3793 | No |
| 56 | DEFB130B | defensin beta 130B [Source:HGNC Symbol;Acc:HGNC:39814] | 22030 | 0.000 | 0.3792 | No |
| 57 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22930 | 0.000 | 0.3550 | No |
| 58 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22932 | 0.000 | 0.3549 | No |
| 59 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 22940 | 0.000 | 0.3547 | No |
| 60 | DEFB103A | defensin beta 103A [Source:HGNC Symbol;Acc:HGNC:15967] | 22982 | 0.000 | 0.3536 | No |
| 61 | DEFB103B | defensin beta 103B [Source:HGNC Symbol;Acc:HGNC:31702] | 22985 | 0.000 | 0.3536 | No |
| 62 | DEFB106B | defensin beta 106B [Source:HGNC Symbol;Acc:HGNC:28879] | 23037 | 0.000 | 0.3522 | No |
| 63 | DEFB106A | defensin beta 106A [Source:HGNC Symbol;Acc:HGNC:18088] | 23044 | 0.000 | 0.3520 | No |
| 64 | DEFB1 | defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766] | 23509 | 0.000 | 0.3395 | No |
| 65 | PF4V1 | platelet factor 4 variant 1 [Source:HGNC Symbol;Acc:HGNC:8862] | 27134 | 0.000 | 0.2416 | No |
| 66 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27677 | -0.024 | 0.2281 | No |
| 67 | ITCH | itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890] | 28814 | -0.156 | 0.2050 | No |
| 68 | S100A14 | S100 calcium binding protein A14 [Source:HGNC Symbol;Acc:HGNC:18901] | 30607 | -0.383 | 0.1751 | No |
