Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | HP_POSTAXIAL_HAND_POLYDACTYLY |
| Enrichment Score (ES) | -0.7451741 |
| Normalized Enrichment Score (NES) | -1.5732919 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.12936567 |
| FWER p-Value | 0.931 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 641 | 1.798 | 0.0024 | No |
| 2 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 947 | 1.457 | 0.0101 | No |
| 3 | BBS4 | Bardet-Biedl syndrome 4 [Source:HGNC Symbol;Acc:HGNC:969] | 1327 | 1.187 | 0.0129 | No |
| 4 | BBIP1 | BBSome interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:28093] | 2281 | 0.790 | -0.0042 | No |
| 5 | SMOC1 | SPARC related modular calcium binding 1 [Source:HGNC Symbol;Acc:HGNC:20318] | 3380 | 0.512 | -0.0282 | No |
| 6 | TRIM32 | tripartite motif containing 32 [Source:HGNC Symbol;Acc:HGNC:16380] | 3939 | 0.410 | -0.0388 | No |
| 7 | PLAA | phospholipase A2 activating protein [Source:HGNC Symbol;Acc:HGNC:9043] | 4034 | 0.390 | -0.0371 | No |
| 8 | MKKS | McKusick-Kaufman syndrome [Source:HGNC Symbol;Acc:HGNC:7108] | 4079 | 0.383 | -0.0341 | No |
| 9 | PRKACB | protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381] | 4092 | 0.381 | -0.0302 | No |
| 10 | BBS12 | Bardet-Biedl syndrome 12 [Source:HGNC Symbol;Acc:HGNC:26648] | 4274 | 0.349 | -0.0313 | No |
| 11 | OFD1 | OFD1 centriole and centriolar satellite protein [Source:HGNC Symbol;Acc:HGNC:2567] | 4923 | 0.244 | -0.0461 | No |
| 12 | LZTFL1 | leucine zipper transcription factor like 1 [Source:HGNC Symbol;Acc:HGNC:6741] | 5006 | 0.232 | -0.0458 | No |
| 13 | RAB23 | RAB23, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14263] | 5637 | 0.140 | -0.0613 | No |
| 14 | BBS1 | Bardet-Biedl syndrome 1 [Source:HGNC Symbol;Acc:HGNC:966] | 5768 | 0.121 | -0.0635 | No |
| 15 | BMPR1B | bone morphogenetic protein receptor type 1B [Source:HGNC Symbol;Acc:HGNC:1077] | 5932 | 0.103 | -0.0668 | No |
| 16 | ZNF141 | zinc finger protein 141 [Source:HGNC Symbol;Acc:HGNC:12926] | 5962 | 0.099 | -0.0664 | No |
| 17 | MEGF8 | multiple EGF like domains 8 [Source:HGNC Symbol;Acc:HGNC:3233] | 6334 | 0.050 | -0.0759 | No |
| 18 | HOXA13 | homeobox A13 [Source:HGNC Symbol;Acc:HGNC:5102] | 6386 | 0.044 | -0.0768 | No |
| 19 | CEP290 | centrosomal protein 290 [Source:HGNC Symbol;Acc:HGNC:29021] | 6423 | 0.040 | -0.0774 | No |
| 20 | KIAA0825 | KIAA0825 [Source:HGNC Symbol;Acc:HGNC:28532] | 6673 | 0.000 | -0.0841 | No |
| 21 | FGFR2 | fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689] | 7484 | 0.000 | -0.1060 | No |
| 22 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 13602 | 0.000 | -0.2713 | No |
| 23 | SETBP1 | SET binding protein 1 [Source:HGNC Symbol;Acc:HGNC:15573] | 14100 | 0.000 | -0.2847 | No |
| 24 | BHLHA9 | basic helix-loop-helix family member a9 [Source:HGNC Symbol;Acc:HGNC:35126] | 15591 | 0.000 | -0.3250 | No |
| 25 | EVC | EvC ciliary complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:3497] | 16598 | 0.000 | -0.3522 | No |
| 26 | TBX3 | T-box transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11602] | 19699 | 0.000 | -0.4360 | No |
| 27 | SHH | sonic hedgehog signaling molecule [Source:HGNC Symbol;Acc:HGNC:10848] | 20855 | 0.000 | -0.4672 | No |
| 28 | GLI3 | GLI family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:4319] | 21772 | 0.000 | -0.4920 | No |
| 29 | GLI2 | GLI family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:4318] | 21773 | 0.000 | -0.4920 | No |
| 30 | TCTN2 | tectonic family member 2 [Source:HGNC Symbol;Acc:HGNC:25774] | 22453 | 0.000 | -0.5103 | No |
| 31 | GPC3 | glypican 3 [Source:HGNC Symbol;Acc:HGNC:4451] | 23074 | 0.000 | -0.5271 | No |
| 32 | GPC4 | glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452] | 23080 | 0.000 | -0.5272 | No |
| 33 | CD96 | CD96 molecule [Source:HGNC Symbol;Acc:HGNC:16892] | 23113 | 0.000 | -0.5281 | No |
| 34 | EVC2 | EvC ciliary complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:19747] | 23491 | 0.000 | -0.5383 | No |
| 35 | WNT7A | Wnt family member 7A [Source:HGNC Symbol;Acc:HGNC:12786] | 24160 | 0.000 | -0.5563 | No |
| 36 | ALX3 | ALX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:449] | 24498 | 0.000 | -0.5654 | No |
| 37 | MBTPS2 | membrane bound transcription factor peptidase, site 2 [Source:HGNC Symbol;Acc:HGNC:15455] | 27642 | -0.019 | -0.6502 | No |
| 38 | C2CD3 | C2 domain containing 3 centriole elongation regulator [Source:HGNC Symbol;Acc:HGNC:24564] | 27931 | -0.055 | -0.6573 | No |
| 39 | TMEM67 | transmembrane protein 67 [Source:HGNC Symbol;Acc:HGNC:28396] | 28693 | -0.142 | -0.6764 | No |
| 40 | SUFU | SUFU negative regulator of hedgehog signaling [Source:HGNC Symbol;Acc:HGNC:16466] | 29266 | -0.213 | -0.6895 | No |
| 41 | TMEM216 | transmembrane protein 216 [Source:HGNC Symbol;Acc:HGNC:25018] | 29417 | -0.231 | -0.6910 | No |
| 42 | TMCO1 | transmembrane and coiled-coil domains 1 [Source:HGNC Symbol;Acc:HGNC:18188] | 29545 | -0.245 | -0.6917 | No |
| 43 | DYNC2H1 | dynein cytoplasmic 2 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2962] | 30395 | -0.354 | -0.7108 | No |
| 44 | TTC8 | tetratricopeptide repeat domain 8 [Source:HGNC Symbol;Acc:HGNC:20087] | 30905 | -0.427 | -0.7199 | No |
| 45 | B9D2 | B9 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28636] | 31315 | -0.487 | -0.7256 | No |
| 46 | MKS1 | MKS transition zone complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:7121] | 31627 | -0.544 | -0.7280 | No |
| 47 | BBS5 | Bardet-Biedl syndrome 5 [Source:HGNC Symbol;Acc:HGNC:970] | 32123 | -0.637 | -0.7344 | No |
| 48 | RPGRIP1 | RPGR interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:13436] | 32522 | -0.717 | -0.7373 | Yes |
| 49 | INPP5E | inositol polyphosphate-5-phosphatase E [Source:HGNC Symbol;Acc:HGNC:21474] | 32609 | -0.737 | -0.7315 | Yes |
| 50 | SDCCAG8 | SHH signaling and ciliogenesis regulator SDCCAG8 [Source:HGNC Symbol;Acc:HGNC:10671] | 32677 | -0.753 | -0.7251 | Yes |
| 51 | RPGRIP1L | RPGRIP1 like [Source:HGNC Symbol;Acc:HGNC:29168] | 32917 | -0.813 | -0.7226 | Yes |
| 52 | TCTN3 | tectonic family member 3 [Source:HGNC Symbol;Acc:HGNC:24519] | 33409 | -0.942 | -0.7256 | Yes |
| 53 | ARL6 | ADP ribosylation factor like GTPase 6 [Source:HGNC Symbol;Acc:HGNC:13210] | 33557 | -0.985 | -0.7188 | Yes |
| 54 | ARMC9 | armadillo repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:20730] | 33639 | -1.010 | -0.7099 | Yes |
| 55 | SC5D | sterol-C5-desaturase [Source:HGNC Symbol;Acc:HGNC:10547] | 33659 | -1.018 | -0.6992 | Yes |
| 56 | PDE6D | phosphodiesterase 6D [Source:HGNC Symbol;Acc:HGNC:8788] | 33824 | -1.071 | -0.6919 | Yes |
| 57 | BBS10 | Bardet-Biedl syndrome 10 [Source:HGNC Symbol;Acc:HGNC:26291] | 34238 | -1.210 | -0.6898 | Yes |
| 58 | BBS9 | Bardet-Biedl syndrome 9 [Source:HGNC Symbol;Acc:HGNC:30000] | 34240 | -1.211 | -0.6765 | Yes |
| 59 | CEP120 | centrosomal protein 120 [Source:HGNC Symbol;Acc:HGNC:26690] | 34289 | -1.229 | -0.6644 | Yes |
| 60 | CCDC28B | coiled-coil domain containing 28B [Source:HGNC Symbol;Acc:HGNC:28163] | 34297 | -1.231 | -0.6510 | Yes |
| 61 | CSPP1 | centrosome and spindle pole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:26193] | 34470 | -1.301 | -0.6414 | Yes |
| 62 | AKT3 | AKT serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:393] | 34521 | -1.319 | -0.6283 | Yes |
| 63 | DDX59 | DEAD-box helicase 59 [Source:HGNC Symbol;Acc:HGNC:25360] | 34579 | -1.345 | -0.6151 | Yes |
| 64 | LMBR1 | limb development membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:13243] | 34650 | -1.373 | -0.6019 | Yes |
| 65 | CC2D2A | coiled-coil and C2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:29253] | 34797 | -1.435 | -0.5901 | Yes |
| 66 | KIF7 | kinesin family member 7 [Source:HGNC Symbol;Acc:HGNC:30497] | 34814 | -1.441 | -0.5747 | Yes |
| 67 | TMEM107 | transmembrane protein 107 [Source:HGNC Symbol;Acc:HGNC:28128] | 34979 | -1.506 | -0.5627 | Yes |
| 68 | TMEM231 | transmembrane protein 231 [Source:HGNC Symbol;Acc:HGNC:37234] | 35114 | -1.572 | -0.5490 | Yes |
| 69 | IFT80 | intraflagellar transport 80 [Source:HGNC Symbol;Acc:HGNC:29262] | 35248 | -1.645 | -0.5346 | Yes |
| 70 | IFT27 | intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626] | 35309 | -1.678 | -0.5178 | Yes |
| 71 | HYLS1 | HYLS1 centriolar and ciliogenesis associated [Source:HGNC Symbol;Acc:HGNC:26558] | 35410 | -1.730 | -0.5015 | Yes |
| 72 | TTC21B | tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660] | 35417 | -1.733 | -0.4827 | Yes |
| 73 | B9D1 | B9 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24123] | 35439 | -1.743 | -0.4641 | Yes |
| 74 | NEK1 | NIMA related kinase 1 [Source:HGNC Symbol;Acc:HGNC:7744] | 35607 | -1.839 | -0.4485 | Yes |
| 75 | DYNC2LI1 | dynein cytoplasmic 2 light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:24595] | 35638 | -1.866 | -0.4288 | Yes |
| 76 | TGFBR1 | transforming growth factor beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772] | 35684 | -1.898 | -0.4092 | Yes |
| 77 | WDR35 | WD repeat domain 35 [Source:HGNC Symbol;Acc:HGNC:29250] | 35748 | -1.933 | -0.3897 | Yes |
| 78 | BBS2 | Bardet-Biedl syndrome 2 [Source:HGNC Symbol;Acc:HGNC:967] | 35829 | -1.996 | -0.3700 | Yes |
| 79 | BBS7 | Bardet-Biedl syndrome 7 [Source:HGNC Symbol;Acc:HGNC:18758] | 35894 | -2.040 | -0.3494 | Yes |
| 80 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 35988 | -2.120 | -0.3286 | Yes |
| 81 | NPHP1 | nephrocystin 1 [Source:HGNC Symbol;Acc:HGNC:7905] | 36088 | -2.209 | -0.3071 | Yes |
| 82 | SMO | smoothened, frizzled class receptor [Source:HGNC Symbol;Acc:HGNC:11119] | 36263 | -2.369 | -0.2858 | Yes |
| 83 | PIK3R2 | phosphoinositide-3-kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:8980] | 36402 | -2.520 | -0.2619 | Yes |
| 84 | C8orf37 | chromosome 8 open reading frame 37 [Source:HGNC Symbol;Acc:HGNC:27232] | 36459 | -2.583 | -0.2351 | Yes |
| 85 | WDR19 | WD repeat domain 19 [Source:HGNC Symbol;Acc:HGNC:18340] | 36496 | -2.646 | -0.2070 | Yes |
| 86 | DHCR7 | 7-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2860] | 36509 | -2.655 | -0.1782 | Yes |
| 87 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 36520 | -2.674 | -0.1492 | Yes |
| 88 | IFT172 | intraflagellar transport 172 [Source:HGNC Symbol;Acc:HGNC:30391] | 36540 | -2.715 | -0.1199 | Yes |
| 89 | PORCN | porcupine O-acyltransferase [Source:HGNC Symbol;Acc:HGNC:17652] | 36579 | -2.756 | -0.0907 | Yes |
| 90 | CIBAR1 | CBY1 interacting BAR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30452] | 36603 | -2.781 | -0.0608 | Yes |
| 91 | WDPCP | WD repeat containing planar cell polarity effector [Source:HGNC Symbol;Acc:HGNC:28027] | 36813 | -3.234 | -0.0310 | Yes |
| 92 | IFT140 | intraflagellar transport 140 [Source:HGNC Symbol;Acc:HGNC:29077] | 36915 | -3.505 | 0.0047 | Yes |
