Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.57420146 |
| Normalized Enrichment Score (NES) | 1.4981234 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07020829 |
| FWER p-Value | 0.088 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 1 | 4.986 | 0.0493 | Yes |
| 2 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 7 | 4.847 | 0.0971 | Yes |
| 3 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 34 | 4.337 | 0.1394 | Yes |
| 4 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 35 | 4.322 | 0.1821 | Yes |
| 5 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 49 | 4.118 | 0.2225 | Yes |
| 6 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 218 | 2.817 | 0.2459 | Yes |
| 7 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 245 | 2.710 | 0.2720 | Yes |
| 8 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 296 | 2.524 | 0.2956 | Yes |
| 9 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 365 | 2.347 | 0.3170 | Yes |
| 10 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 395 | 2.280 | 0.3388 | Yes |
| 11 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 456 | 2.138 | 0.3583 | Yes |
| 12 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 529 | 2.006 | 0.3762 | Yes |
| 13 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 616 | 1.846 | 0.3922 | Yes |
| 14 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 641 | 1.798 | 0.4093 | Yes |
| 15 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 682 | 1.742 | 0.4255 | Yes |
| 16 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 1076 | 1.351 | 0.4282 | Yes |
| 17 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 1187 | 1.267 | 0.4378 | Yes |
| 18 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 1253 | 1.222 | 0.4481 | Yes |
| 19 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 1399 | 1.159 | 0.4557 | Yes |
| 20 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 1677 | 1.024 | 0.4583 | Yes |
| 21 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 1767 | 0.978 | 0.4656 | Yes |
| 22 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 1772 | 0.976 | 0.4751 | Yes |
| 23 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 1915 | 0.924 | 0.4804 | Yes |
| 24 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 1980 | 0.900 | 0.4876 | Yes |
| 25 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 2042 | 0.876 | 0.4946 | Yes |
| 26 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 2088 | 0.860 | 0.5019 | Yes |
| 27 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 2117 | 0.850 | 0.5096 | Yes |
| 28 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 2167 | 0.830 | 0.5164 | Yes |
| 29 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 2245 | 0.801 | 0.5223 | Yes |
| 30 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 2370 | 0.763 | 0.5265 | Yes |
| 31 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2410 | 0.753 | 0.5329 | Yes |
| 32 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 2661 | 0.674 | 0.5328 | Yes |
| 33 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 2689 | 0.668 | 0.5387 | Yes |
| 34 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 2741 | 0.655 | 0.5438 | Yes |
| 35 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 3056 | 0.578 | 0.5410 | Yes |
| 36 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 3092 | 0.574 | 0.5457 | Yes |
| 37 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 3153 | 0.561 | 0.5497 | Yes |
| 38 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 3252 | 0.540 | 0.5524 | Yes |
| 39 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 3288 | 0.532 | 0.5567 | Yes |
| 40 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 3305 | 0.528 | 0.5615 | Yes |
| 41 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 3491 | 0.491 | 0.5613 | Yes |
| 42 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 3857 | 0.427 | 0.5557 | Yes |
| 43 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 3865 | 0.426 | 0.5597 | Yes |
| 44 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 3888 | 0.420 | 0.5633 | Yes |
| 45 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 3957 | 0.405 | 0.5654 | Yes |
| 46 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 3986 | 0.399 | 0.5686 | Yes |
| 47 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 3998 | 0.397 | 0.5723 | Yes |
| 48 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 4068 | 0.385 | 0.5742 | Yes |
| 49 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 4462 | 0.319 | 0.5667 | No |
| 50 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 4811 | 0.262 | 0.5599 | No |
| 51 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 5199 | 0.204 | 0.5514 | No |
| 52 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 5388 | 0.174 | 0.5481 | No |
| 53 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 5474 | 0.163 | 0.5474 | No |
| 54 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 5572 | 0.150 | 0.5463 | No |
| 55 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 5610 | 0.145 | 0.5467 | No |
| 56 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 5865 | 0.111 | 0.5409 | No |
| 57 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 5939 | 0.102 | 0.5400 | No |
| 58 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 5965 | 0.099 | 0.5403 | No |
| 59 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 6103 | 0.080 | 0.5374 | No |
| 60 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 6843 | 0.000 | 0.5174 | No |
| 61 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 9033 | 0.000 | 0.4582 | No |
| 62 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9671 | 0.000 | 0.4409 | No |
| 63 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 10012 | 0.000 | 0.4317 | No |
| 64 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 10198 | 0.000 | 0.4267 | No |
| 65 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11212 | 0.000 | 0.3993 | No |
| 66 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11329 | 0.000 | 0.3962 | No |
| 67 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11369 | 0.000 | 0.3951 | No |
| 68 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11919 | 0.000 | 0.3803 | No |
| 69 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11993 | 0.000 | 0.3783 | No |
| 70 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 12308 | 0.000 | 0.3698 | No |
| 71 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12674 | 0.000 | 0.3599 | No |
| 72 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 13200 | 0.000 | 0.3457 | No |
| 73 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 14006 | 0.000 | 0.3240 | No |
| 74 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 14307 | 0.000 | 0.3158 | No |
| 75 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16442 | 0.000 | 0.2581 | No |
| 76 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17185 | 0.000 | 0.2381 | No |
| 77 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 18002 | 0.000 | 0.2160 | No |
| 78 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19250 | 0.000 | 0.1822 | No |
| 79 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 20945 | 0.000 | 0.1364 | No |
| 80 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 21188 | 0.000 | 0.1299 | No |
| 81 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 21894 | 0.000 | 0.1108 | No |
| 82 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 22788 | 0.000 | 0.0867 | No |
| 83 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23782 | 0.000 | 0.0598 | No |
| 84 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 24552 | 0.000 | 0.0390 | No |
| 85 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 24756 | 0.000 | 0.0335 | No |
| 86 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 25148 | 0.000 | 0.0229 | No |
| 87 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 25856 | 0.000 | 0.0038 | No |
| 88 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 27012 | 0.000 | -0.0274 | No |
| 89 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 27683 | -0.024 | -0.0453 | No |
| 90 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 27732 | -0.030 | -0.0463 | No |
| 91 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 27925 | -0.054 | -0.0510 | No |
| 92 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 28219 | -0.086 | -0.0581 | No |
| 93 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 28561 | -0.126 | -0.0660 | No |
| 94 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 28773 | -0.152 | -0.0703 | No |
| 95 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 29515 | -0.243 | -0.0879 | No |
| 96 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 29944 | -0.300 | -0.0965 | No |
| 97 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 30155 | -0.324 | -0.0990 | No |
| 98 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 30193 | -0.330 | -0.0967 | No |
| 99 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 30477 | -0.363 | -0.1008 | No |
| 100 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 30482 | -0.365 | -0.0973 | No |
| 101 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 30676 | -0.392 | -0.0986 | No |
| 102 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 30712 | -0.397 | -0.0956 | No |
| 103 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 30948 | -0.431 | -0.0977 | No |
| 104 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 31054 | -0.448 | -0.0961 | No |
| 105 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 31491 | -0.520 | -0.1028 | No |
| 106 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 31591 | -0.538 | -0.1001 | No |
| 107 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 31687 | -0.557 | -0.0972 | No |
| 108 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 31950 | -0.599 | -0.0984 | No |
| 109 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 32230 | -0.660 | -0.0994 | No |
| 110 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 32277 | -0.669 | -0.0940 | No |
| 111 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 32333 | -0.679 | -0.0888 | No |
| 112 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 33254 | -0.903 | -0.1047 | No |
| 113 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 33472 | -0.959 | -0.1011 | No |
| 114 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 34245 | -1.212 | -0.1100 | No |
| 115 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 34478 | -1.304 | -0.1033 | No |
| 116 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 34494 | -1.310 | -0.0908 | No |
| 117 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35196 | -1.611 | -0.0938 | No |
| 118 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 35513 | -1.779 | -0.0847 | No |
| 119 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 35753 | -1.939 | -0.0720 | No |
| 120 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35854 | -2.011 | -0.0548 | No |
| 121 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 36022 | -2.154 | -0.0380 | No |
| 122 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36720 | -2.988 | -0.0273 | No |
| 123 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36972 | -3.766 | 0.0032 | No |
