Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_DN.V1_UP |
| Enrichment Score (ES) | -0.6645414 |
| Normalized Enrichment Score (NES) | -1.4317666 |
| Nominal p-value | 0.0011325028 |
| FDR q-value | 0.06443271 |
| FWER p-Value | 0.361 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ID1 | inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360] | 24 | 4.487 | 0.0312 | No |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 47 | 4.168 | 0.0602 | No |
| 3 | BTG2 | BTG anti-proliferation factor 2 [Source:HGNC Symbol;Acc:HGNC:1131] | 436 | 2.177 | 0.0652 | No |
| 4 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 563 | 1.945 | 0.0756 | No |
| 5 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 673 | 1.758 | 0.0851 | No |
| 6 | ZSCAN22 | zinc finger and SCAN domain containing 22 [Source:HGNC Symbol;Acc:HGNC:4929] | 1001 | 1.413 | 0.0863 | No |
| 7 | MDM2 | MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973] | 1079 | 1.349 | 0.0938 | No |
| 8 | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864] | 1227 | 1.237 | 0.0986 | No |
| 9 | PRKAB1 | protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378] | 1352 | 1.178 | 0.1036 | No |
| 10 | MAN1B1 | mannosidase alpha class 1B member 1 [Source:HGNC Symbol;Acc:HGNC:6823] | 2333 | 0.774 | 0.0826 | No |
| 11 | TGM1 | transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777] | 2440 | 0.744 | 0.0850 | No |
| 12 | PLA2G6 | phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039] | 2662 | 0.674 | 0.0838 | No |
| 13 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 2962 | 0.597 | 0.0800 | No |
| 14 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 2973 | 0.593 | 0.0839 | No |
| 15 | SLC7A7 | solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065] | 3003 | 0.587 | 0.0873 | No |
| 16 | PRKCE | protein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401] | 4498 | 0.313 | 0.0491 | No |
| 17 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 4737 | 0.274 | 0.0446 | No |
| 18 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 6630 | 0.008 | -0.0065 | No |
| 19 | FXYD6 | FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030] | 6984 | 0.000 | -0.0161 | No |
| 20 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 7515 | 0.000 | -0.0304 | No |
| 21 | ARTN | artemin [Source:HGNC Symbol;Acc:HGNC:727] | 7790 | 0.000 | -0.0378 | No |
| 22 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9128 | 0.000 | -0.0740 | No |
| 23 | TNFRSF18 | TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914] | 9513 | 0.000 | -0.0843 | No |
| 24 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 10135 | 0.000 | -0.1011 | No |
| 25 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 10137 | 0.000 | -0.1012 | No |
| 26 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 10234 | 0.000 | -0.1038 | No |
| 27 | OVOL2 | ovo like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:15804] | 10971 | 0.000 | -0.1237 | No |
| 28 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11757 | 0.000 | -0.1449 | No |
| 29 | IL36RN | interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561] | 12739 | 0.000 | -0.1714 | No |
| 30 | DDIT4L | DNA damage inducible transcript 4 like [Source:HGNC Symbol;Acc:HGNC:30555] | 13598 | 0.000 | -0.1946 | No |
| 31 | MANSC1 | MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505] | 14075 | 0.000 | -0.2075 | No |
| 32 | PCDH10 | protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404] | 14777 | 0.000 | -0.2265 | No |
| 33 | NOXO1 | NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] | 15534 | 0.000 | -0.2469 | No |
| 34 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16122 | 0.000 | -0.2628 | No |
| 35 | PALMD | palmdelphin [Source:HGNC Symbol;Acc:HGNC:15846] | 16764 | 0.000 | -0.2801 | No |
| 36 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17119 | 0.000 | -0.2897 | No |
| 37 | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [Source:HGNC Symbol;Acc:HGNC:11097] | 19728 | 0.000 | -0.3602 | No |
| 38 | TMEM54 | transmembrane protein 54 [Source:HGNC Symbol;Acc:HGNC:24143] | 20211 | 0.000 | -0.3733 | No |
| 39 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21884 | 0.000 | -0.4185 | No |
| 40 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 23654 | 0.000 | -0.4663 | No |
| 41 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 24199 | 0.000 | -0.4811 | No |
| 42 | ALPK3 | alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:17574] | 25077 | 0.000 | -0.5048 | No |
| 43 | DUOXA1 | dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] | 25948 | 0.000 | -0.5283 | No |
| 44 | UCK1 | uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859] | 27701 | -0.026 | -0.5755 | No |
| 45 | MAPK13 | mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875] | 28176 | -0.082 | -0.5877 | No |
| 46 | HEY2 | hes related family bHLH transcription factor with YRPW motif 2 [Source:HGNC Symbol;Acc:HGNC:4881] | 28300 | -0.096 | -0.5904 | No |
| 47 | POLD4 | DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106] | 28574 | -0.127 | -0.5969 | No |
| 48 | SLC24A1 | solute carrier family 24 member 1 [Source:HGNC Symbol;Acc:HGNC:10975] | 28777 | -0.152 | -0.6013 | No |
| 49 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30286 | -0.341 | -0.6396 | No |
| 50 | DNASE1L1 | deoxyribonuclease 1 like 1 [Source:HGNC Symbol;Acc:HGNC:2957] | 30843 | -0.417 | -0.6517 | No |
| 51 | AHCY | adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343] | 31121 | -0.457 | -0.6559 | No |
| 52 | NUDT5 | nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052] | 31153 | -0.462 | -0.6535 | No |
| 53 | MRPL49 | mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:HGNC:1176] | 31283 | -0.482 | -0.6536 | No |
| 54 | PLEKHA6 | pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053] | 31690 | -0.558 | -0.6606 | Yes |
| 55 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 31705 | -0.560 | -0.6570 | Yes |
| 56 | BAZ1B | bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961] | 31927 | -0.594 | -0.6587 | Yes |
| 57 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 32134 | -0.639 | -0.6598 | Yes |
| 58 | ZW10 | zw10 kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13194] | 32144 | -0.641 | -0.6555 | Yes |
| 59 | GNB1L | G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397] | 32150 | -0.642 | -0.6510 | Yes |
| 60 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 32315 | -0.677 | -0.6507 | Yes |
| 61 | PDXP | pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259] | 32724 | -0.764 | -0.6563 | Yes |
| 62 | AAAS | aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666] | 32802 | -0.783 | -0.6528 | Yes |
| 63 | EI24 | EI24 autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276] | 32836 | -0.793 | -0.6481 | Yes |
| 64 | ZFP30 | ZFP30 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29555] | 32859 | -0.799 | -0.6430 | Yes |
| 65 | NANS | N-acetylneuraminate synthase [Source:HGNC Symbol;Acc:HGNC:19237] | 33027 | -0.839 | -0.6416 | Yes |
| 66 | CTDSP1 | CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614] | 33070 | -0.850 | -0.6367 | Yes |
| 67 | PCBP2 | poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648] | 33321 | -0.919 | -0.6369 | Yes |
| 68 | TIPIN | TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750] | 33437 | -0.948 | -0.6333 | Yes |
| 69 | NUMBL | NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061] | 33444 | -0.951 | -0.6267 | Yes |
| 70 | LCMT1 | leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557] | 33683 | -1.027 | -0.6258 | Yes |
| 71 | TKFC | triokinase and FMN cyclase [Source:HGNC Symbol;Acc:HGNC:24552] | 33879 | -1.088 | -0.6234 | Yes |
| 72 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33988 | -1.124 | -0.6183 | Yes |
| 73 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 34026 | -1.138 | -0.6112 | Yes |
| 74 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 34112 | -1.167 | -0.6053 | Yes |
| 75 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 34250 | -1.213 | -0.6003 | Yes |
| 76 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34299 | -1.231 | -0.5929 | Yes |
| 77 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 34387 | -1.263 | -0.5863 | Yes |
| 78 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 34452 | -1.295 | -0.5788 | Yes |
| 79 | SPICE1 | spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083] | 34540 | -1.329 | -0.5717 | Yes |
| 80 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 34549 | -1.332 | -0.5625 | Yes |
| 81 | MMGT1 | membrane magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28100] | 34561 | -1.338 | -0.5533 | Yes |
| 82 | SULF2 | sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392] | 34684 | -1.383 | -0.5468 | Yes |
| 83 | STUB1 | STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427] | 34897 | -1.473 | -0.5420 | Yes |
| 84 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 34986 | -1.510 | -0.5337 | Yes |
| 85 | IFT27 | intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626] | 35309 | -1.678 | -0.5305 | Yes |
| 86 | PLXNB2 | plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104] | 35361 | -1.704 | -0.5198 | Yes |
| 87 | PMS2 | PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122] | 35635 | -1.862 | -0.5139 | Yes |
| 88 | VPS16 | VPS16 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14584] | 35658 | -1.879 | -0.5012 | Yes |
| 89 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 35693 | -1.899 | -0.4886 | Yes |
| 90 | PPM1M | protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] | 35856 | -2.012 | -0.4787 | Yes |
| 91 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 35868 | -2.020 | -0.4647 | Yes |
| 92 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35905 | -2.049 | -0.4511 | Yes |
| 93 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 36002 | -2.139 | -0.4385 | Yes |
| 94 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36028 | -2.161 | -0.4238 | Yes |
| 95 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36065 | -2.187 | -0.4093 | Yes |
| 96 | TPRA1 | transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413] | 36118 | -2.239 | -0.3948 | Yes |
| 97 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 36131 | -2.249 | -0.3792 | Yes |
| 98 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36145 | -2.264 | -0.3634 | Yes |
| 99 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36182 | -2.302 | -0.3481 | Yes |
| 100 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36241 | -2.351 | -0.3329 | Yes |
| 101 | SLC2A9 | solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446] | 36278 | -2.384 | -0.3170 | Yes |
| 102 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36289 | -2.396 | -0.3002 | Yes |
| 103 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36377 | -2.484 | -0.2850 | Yes |
| 104 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36442 | -2.562 | -0.2685 | Yes |
| 105 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36468 | -2.596 | -0.2507 | Yes |
| 106 | EPHX1 | epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401] | 36543 | -2.718 | -0.2335 | Yes |
| 107 | NME4 | NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852] | 36554 | -2.726 | -0.2144 | Yes |
| 108 | THRA | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | 36629 | -2.819 | -0.1964 | Yes |
| 109 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 36637 | -2.827 | -0.1765 | Yes |
| 110 | GANC | glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139] | 36652 | -2.847 | -0.1566 | Yes |
| 111 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36694 | -2.936 | -0.1369 | Yes |
| 112 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36818 | -3.244 | -0.1172 | Yes |
| 113 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36823 | -3.251 | -0.0942 | Yes |
| 114 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36844 | -3.302 | -0.0713 | Yes |
| 115 | SLC2A8 | solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812] | 36884 | -3.400 | -0.0482 | Yes |
| 116 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36958 | -3.700 | -0.0239 | Yes |
| 117 | PMM1 | phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114] | 36995 | -3.871 | 0.0026 | Yes |
