Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.7410191 |
| Normalized Enrichment Score (NES) | -1.6125722 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0068222233 |
| FWER p-Value | 0.008 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 61 | 3.986 | 0.0235 | No |
| 2 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 210 | 2.872 | 0.0377 | No |
| 3 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 506 | 2.036 | 0.0426 | No |
| 4 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 1115 | 1.318 | 0.0345 | No |
| 5 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 1502 | 1.109 | 0.0310 | No |
| 6 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 1878 | 0.934 | 0.0268 | No |
| 7 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 2044 | 0.875 | 0.0279 | No |
| 8 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 2219 | 0.814 | 0.0283 | No |
| 9 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 2973 | 0.593 | 0.0117 | No |
| 10 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 3297 | 0.530 | 0.0063 | No |
| 11 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 4177 | 0.365 | -0.0152 | No |
| 12 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 4737 | 0.274 | -0.0286 | No |
| 13 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 5151 | 0.211 | -0.0384 | No |
| 14 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 5246 | 0.196 | -0.0397 | No |
| 15 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 5602 | 0.146 | -0.0484 | No |
| 16 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 6071 | 0.085 | -0.0605 | No |
| 17 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 7041 | 0.000 | -0.0867 | No |
| 18 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 8410 | 0.000 | -0.1238 | No |
| 19 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9941 | 0.000 | -0.1651 | No |
| 20 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 9981 | 0.000 | -0.1662 | No |
| 21 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10813 | 0.000 | -0.1887 | No |
| 22 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 12260 | 0.000 | -0.2278 | No |
| 23 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12632 | 0.000 | -0.2378 | No |
| 24 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12780 | 0.000 | -0.2418 | No |
| 25 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12822 | 0.000 | -0.2429 | No |
| 26 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 13081 | 0.000 | -0.2499 | No |
| 27 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13669 | 0.000 | -0.2658 | No |
| 28 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14925 | 0.000 | -0.2997 | No |
| 29 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16122 | 0.000 | -0.3321 | No |
| 30 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16343 | 0.000 | -0.3381 | No |
| 31 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16415 | 0.000 | -0.3400 | No |
| 32 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16556 | 0.000 | -0.3438 | No |
| 33 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16650 | 0.000 | -0.3463 | No |
| 34 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17562 | 0.000 | -0.3709 | No |
| 35 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18719 | 0.000 | -0.4022 | No |
| 36 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18720 | 0.000 | -0.4022 | No |
| 37 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 18972 | 0.000 | -0.4090 | No |
| 38 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19634 | 0.000 | -0.4269 | No |
| 39 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19775 | 0.000 | -0.4307 | No |
| 40 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 20327 | 0.000 | -0.4456 | No |
| 41 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 21140 | 0.000 | -0.4675 | No |
| 42 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21370 | 0.000 | -0.4737 | No |
| 43 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21884 | 0.000 | -0.4876 | No |
| 44 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 22456 | 0.000 | -0.5031 | No |
| 45 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 24356 | 0.000 | -0.5545 | No |
| 46 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 25725 | 0.000 | -0.5915 | No |
| 47 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 27647 | -0.021 | -0.6433 | No |
| 48 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 27652 | -0.021 | -0.6433 | No |
| 49 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 27673 | -0.024 | -0.6437 | No |
| 50 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 27980 | -0.059 | -0.6516 | No |
| 51 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 28031 | -0.065 | -0.6525 | No |
| 52 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 28494 | -0.118 | -0.6643 | No |
| 53 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 28896 | -0.167 | -0.6741 | No |
| 54 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 28928 | -0.170 | -0.6738 | No |
| 55 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 29070 | -0.190 | -0.6764 | No |
| 56 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 29092 | -0.192 | -0.6758 | No |
| 57 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 29516 | -0.243 | -0.6857 | No |
| 58 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 29542 | -0.245 | -0.6848 | No |
| 59 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 30051 | -0.312 | -0.6966 | No |
| 60 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30286 | -0.341 | -0.7008 | No |
| 61 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 30492 | -0.365 | -0.7040 | No |
| 62 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 30649 | -0.388 | -0.7058 | No |
| 63 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 31282 | -0.482 | -0.7198 | No |
| 64 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 31397 | -0.504 | -0.7197 | No |
| 65 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31611 | -0.540 | -0.7221 | No |
| 66 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 31681 | -0.555 | -0.7204 | No |
| 67 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 31871 | -0.586 | -0.7219 | No |
| 68 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32050 | -0.618 | -0.7228 | No |
| 69 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 32075 | -0.626 | -0.7195 | No |
| 70 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 32142 | -0.640 | -0.7172 | No |
| 71 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 32255 | -0.665 | -0.7160 | No |
| 72 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 32315 | -0.677 | -0.7133 | No |
| 73 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 33248 | -0.901 | -0.7329 | No |
| 74 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 33286 | -0.912 | -0.7281 | No |
| 75 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 33443 | -0.951 | -0.7263 | No |
| 76 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33988 | -1.124 | -0.7339 | Yes |
| 77 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 34203 | -1.199 | -0.7321 | Yes |
| 78 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 34229 | -1.206 | -0.7252 | Yes |
| 79 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34299 | -1.231 | -0.7193 | Yes |
| 80 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 34408 | -1.272 | -0.7141 | Yes |
| 81 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 34421 | -1.276 | -0.7064 | Yes |
| 82 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 34452 | -1.295 | -0.6990 | Yes |
| 83 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 34620 | -1.362 | -0.6949 | Yes |
| 84 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 34700 | -1.391 | -0.6883 | Yes |
| 85 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 34866 | -1.461 | -0.6835 | Yes |
| 86 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35065 | -1.544 | -0.6791 | Yes |
| 87 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 35231 | -1.633 | -0.6732 | Yes |
| 88 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 35261 | -1.650 | -0.6636 | Yes |
| 89 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 35288 | -1.669 | -0.6537 | Yes |
| 90 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 35395 | -1.722 | -0.6457 | Yes |
| 91 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 35403 | -1.727 | -0.6350 | Yes |
| 92 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35470 | -1.760 | -0.6257 | Yes |
| 93 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 35628 | -1.853 | -0.6182 | Yes |
| 94 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35653 | -1.875 | -0.6070 | Yes |
| 95 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35709 | -1.910 | -0.5964 | Yes |
| 96 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35769 | -1.949 | -0.5857 | Yes |
| 97 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 35868 | -2.020 | -0.5756 | Yes |
| 98 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 35899 | -2.044 | -0.5635 | Yes |
| 99 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35905 | -2.049 | -0.5506 | Yes |
| 100 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35939 | -2.080 | -0.5384 | Yes |
| 101 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36027 | -2.160 | -0.5271 | Yes |
| 102 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36028 | -2.161 | -0.5134 | Yes |
| 103 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36065 | -2.187 | -0.5006 | Yes |
| 104 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36147 | -2.266 | -0.4884 | Yes |
| 105 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36203 | -2.318 | -0.4753 | Yes |
| 106 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36229 | -2.343 | -0.4611 | Yes |
| 107 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 36236 | -2.348 | -0.4465 | Yes |
| 108 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36377 | -2.484 | -0.4345 | Yes |
| 109 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36442 | -2.562 | -0.4201 | Yes |
| 110 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36468 | -2.596 | -0.4043 | Yes |
| 111 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36483 | -2.621 | -0.3882 | Yes |
| 112 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36537 | -2.711 | -0.3725 | Yes |
| 113 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36675 | -2.891 | -0.3579 | Yes |
| 114 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36694 | -2.936 | -0.3398 | Yes |
| 115 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36708 | -2.969 | -0.3214 | Yes |
| 116 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36733 | -3.017 | -0.3030 | Yes |
| 117 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36772 | -3.113 | -0.2843 | Yes |
| 118 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36779 | -3.125 | -0.2647 | Yes |
| 119 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36801 | -3.209 | -0.2450 | Yes |
| 120 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36823 | -3.251 | -0.2250 | Yes |
| 121 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36856 | -3.348 | -0.2047 | Yes |
| 122 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36862 | -3.357 | -0.1836 | Yes |
| 123 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36895 | -3.442 | -0.1628 | Yes |
| 124 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36906 | -3.471 | -0.1411 | Yes |
| 125 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 36927 | -3.556 | -0.1191 | Yes |
| 126 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36958 | -3.700 | -0.0966 | Yes |
| 127 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36977 | -3.801 | -0.0730 | Yes |
| 128 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36988 | -3.855 | -0.0489 | Yes |
| 129 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 37026 | -4.005 | -0.0246 | Yes |
| 130 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 37045 | -4.163 | 0.0012 | Yes |
