Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ZHONG_PFC_C8_ORG_PROLIFERATING |
| Enrichment Score (ES) | -0.82540685 |
| Normalized Enrichment Score (NES) | -1.6582738 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.6943044E-4 |
| FWER p-Value | 0.006 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1522 | 1.100 | -0.0291 | No |
| 2 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 1705 | 1.006 | -0.0230 | No |
| 3 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 3079 | 0.576 | -0.0538 | No |
| 4 | NOTCH2NLA | notch 2 N-terminal like A [Source:HGNC Symbol;Acc:HGNC:31862] | 3923 | 0.413 | -0.0720 | No |
| 5 | TUBB6 | tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776] | 4309 | 0.343 | -0.0787 | No |
| 6 | GAS2L3 | growth arrest specific 2 like 3 [Source:HGNC Symbol;Acc:HGNC:27475] | 5659 | 0.138 | -0.1136 | No |
| 7 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7873 | 0.000 | -0.1734 | No |
| 8 | NMU | neuromedin U [Source:HGNC Symbol;Acc:HGNC:7859] | 19310 | 0.000 | -0.4822 | No |
| 9 | SFRP2 | secreted frizzled related protein 2 [Source:HGNC Symbol;Acc:HGNC:10777] | 23656 | 0.000 | -0.5995 | No |
| 10 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 24136 | 0.000 | -0.6125 | No |
| 11 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 28366 | -0.104 | -0.7255 | No |
| 12 | ITGB1BP1 | integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927] | 28644 | -0.136 | -0.7315 | No |
| 13 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 29208 | -0.205 | -0.7445 | No |
| 14 | UNC50 | unc-50 inner nuclear membrane RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16046] | 29326 | -0.220 | -0.7453 | No |
| 15 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 30309 | -0.343 | -0.7680 | No |
| 16 | CRNDE | colorectal neoplasia differentially expressed [Source:HGNC Symbol;Acc:HGNC:37078] | 30564 | -0.377 | -0.7708 | No |
| 17 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31593 | -0.538 | -0.7926 | No |
| 18 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 32178 | -0.649 | -0.8013 | No |
| 19 | ANXA2 | annexin A2 [Source:HGNC Symbol;Acc:HGNC:537] | 33071 | -0.851 | -0.8161 | Yes |
| 20 | TXNDC12 | thioredoxin domain containing 12 [Source:HGNC Symbol;Acc:HGNC:24626] | 33239 | -0.897 | -0.8108 | Yes |
| 21 | ARL6IP1 | ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697] | 33379 | -0.935 | -0.8043 | Yes |
| 22 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33435 | -0.948 | -0.7954 | Yes |
| 23 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33875 | -1.087 | -0.7954 | Yes |
| 24 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33965 | -1.117 | -0.7856 | Yes |
| 25 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33967 | -1.118 | -0.7734 | Yes |
| 26 | TMEM256 | transmembrane protein 256 [Source:HGNC Symbol;Acc:HGNC:28618] | 34246 | -1.212 | -0.7676 | Yes |
| 27 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 34258 | -1.217 | -0.7546 | Yes |
| 28 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 34653 | -1.373 | -0.7503 | Yes |
| 29 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 34850 | -1.453 | -0.7397 | Yes |
| 30 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34948 | -1.490 | -0.7260 | Yes |
| 31 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35070 | -1.546 | -0.7123 | Yes |
| 32 | MZT1 | mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830] | 35098 | -1.564 | -0.6960 | Yes |
| 33 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35100 | -1.565 | -0.6789 | Yes |
| 34 | CCDC34 | coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079] | 35118 | -1.572 | -0.6622 | Yes |
| 35 | SMTN | smoothelin [Source:HGNC Symbol;Acc:HGNC:11126] | 35197 | -1.615 | -0.6466 | Yes |
| 36 | CRYZ | crystallin zeta [Source:HGNC Symbol;Acc:HGNC:2419] | 35209 | -1.619 | -0.6292 | Yes |
| 37 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35283 | -1.667 | -0.6129 | Yes |
| 38 | ODF2 | outer dense fiber of sperm tails 2 [Source:HGNC Symbol;Acc:HGNC:8114] | 35330 | -1.689 | -0.5957 | Yes |
| 39 | PLIN3 | perilipin 3 [Source:HGNC Symbol;Acc:HGNC:16893] | 35402 | -1.727 | -0.5787 | Yes |
| 40 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35471 | -1.761 | -0.5613 | Yes |
| 41 | TUBA1C | tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768] | 35550 | -1.807 | -0.5437 | Yes |
| 42 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35583 | -1.827 | -0.5245 | Yes |
| 43 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35704 | -1.908 | -0.5069 | Yes |
| 44 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35709 | -1.910 | -0.4861 | Yes |
| 45 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 36109 | -2.234 | -0.4725 | Yes |
| 46 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36111 | -2.235 | -0.4481 | Yes |
| 47 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 36131 | -2.249 | -0.4240 | Yes |
| 48 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36291 | -2.397 | -0.4021 | Yes |
| 49 | KNSTRN | kinetochore localized astrin (SPAG5) binding protein [Source:HGNC Symbol;Acc:HGNC:30767] | 36298 | -2.404 | -0.3759 | Yes |
| 50 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36341 | -2.453 | -0.3502 | Yes |
| 51 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36363 | -2.471 | -0.3238 | Yes |
| 52 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36429 | -2.546 | -0.2977 | Yes |
| 53 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36445 | -2.564 | -0.2701 | Yes |
| 54 | RP2 | RP2 activator of ARL3 GTPase [Source:HGNC Symbol;Acc:HGNC:10274] | 36447 | -2.567 | -0.2420 | Yes |
| 55 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36471 | -2.598 | -0.2142 | Yes |
| 56 | DEPDC1B | DEP domain containing 1B [Source:HGNC Symbol;Acc:HGNC:24902] | 36523 | -2.685 | -0.1862 | Yes |
| 57 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36541 | -2.717 | -0.1570 | Yes |
| 58 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36614 | -2.799 | -0.1283 | Yes |
| 59 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36617 | -2.804 | -0.0977 | Yes |
| 60 | KIF18A | kinesin family member 18A [Source:HGNC Symbol;Acc:HGNC:29441] | 36651 | -2.846 | -0.0675 | Yes |
| 61 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36716 | -2.984 | -0.0366 | Yes |
| 62 | PSRC1 | proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472] | 37058 | -4.264 | 0.0009 | Yes |
