Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | 0.58578753 |
| Normalized Enrichment Score (NES) | 1.3869966 |
| Nominal p-value | 0.02970297 |
| FDR q-value | 0.050990265 |
| FWER p-Value | 0.095 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 15 | 4.682 | 0.0644 | Yes |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 47 | 4.168 | 0.1213 | Yes |
| 3 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 348 | 2.401 | 0.1464 | Yes |
| 4 | GRWD1 | glutamate rich WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:21270] | 389 | 2.296 | 0.1771 | Yes |
| 5 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 466 | 2.111 | 0.2043 | Yes |
| 6 | MYBBP1A | MYB binding protein 1a [Source:HGNC Symbol;Acc:HGNC:7546] | 519 | 2.017 | 0.2308 | Yes |
| 7 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 575 | 1.922 | 0.2560 | Yes |
| 8 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 598 | 1.878 | 0.2814 | Yes |
| 9 | NOP2 | NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867] | 635 | 1.807 | 0.3054 | Yes |
| 10 | NOP16 | NOP16 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:26934] | 856 | 1.544 | 0.3208 | Yes |
| 11 | TCOF1 | treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654] | 898 | 1.504 | 0.3406 | Yes |
| 12 | WDR43 | WD repeat domain 43 [Source:HGNC Symbol;Acc:HGNC:28945] | 997 | 1.417 | 0.3575 | Yes |
| 13 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 1126 | 1.312 | 0.3722 | Yes |
| 14 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 1138 | 1.302 | 0.3900 | Yes |
| 15 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 1236 | 1.233 | 0.4044 | Yes |
| 16 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 1343 | 1.180 | 0.4179 | Yes |
| 17 | DDX18 | DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741] | 1367 | 1.171 | 0.4335 | Yes |
| 18 | PPRC1 | PPARG related coactivator 1 [Source:HGNC Symbol;Acc:HGNC:30025] | 1432 | 1.142 | 0.4476 | Yes |
| 19 | HK2 | hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923] | 1561 | 1.081 | 0.4591 | Yes |
| 20 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 1600 | 1.066 | 0.4728 | Yes |
| 21 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 1649 | 1.039 | 0.4859 | Yes |
| 22 | GNL3 | G protein nucleolar 3 [Source:HGNC Symbol;Acc:HGNC:29931] | 1674 | 1.025 | 0.4994 | Yes |
| 23 | PUS1 | pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:15508] | 1748 | 0.985 | 0.5111 | Yes |
| 24 | PHB | prohibitin [Source:HGNC Symbol;Acc:HGNC:8912] | 1824 | 0.951 | 0.5222 | Yes |
| 25 | FARSA | phenylalanyl-tRNA synthetase subunit alpha [Source:HGNC Symbol;Acc:HGNC:3592] | 1839 | 0.947 | 0.5350 | Yes |
| 26 | SRM | spermidine synthase [Source:HGNC Symbol;Acc:HGNC:11296] | 1924 | 0.920 | 0.5455 | Yes |
| 27 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 1979 | 0.900 | 0.5565 | Yes |
| 28 | RCL1 | RNA terminal phosphate cyclase like 1 [Source:HGNC Symbol;Acc:HGNC:17687] | 2233 | 0.806 | 0.5608 | Yes |
| 29 | NOLC1 | nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608] | 2292 | 0.786 | 0.5701 | Yes |
| 30 | HSPD1 | heat shock protein family D (Hsp60) member 1 [Source:HGNC Symbol;Acc:HGNC:5261] | 2427 | 0.747 | 0.5768 | Yes |
| 31 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 2471 | 0.731 | 0.5858 | Yes |
| 32 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 3028 | 0.584 | 0.5789 | No |
| 33 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 3282 | 0.533 | 0.5794 | No |
| 34 | SLC19A1 | solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937] | 3698 | 0.456 | 0.5745 | No |
| 35 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 4071 | 0.385 | 0.5698 | No |
| 36 | NDUFAF4 | NADH:ubiquinone oxidoreductase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21034] | 4241 | 0.353 | 0.5701 | No |
| 37 | NPM1 | nucleophosmin 1 [Source:HGNC Symbol;Acc:HGNC:7910] | 4477 | 0.317 | 0.5681 | No |
| 38 | AIMP2 | aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:HGNC:20609] | 4921 | 0.244 | 0.5596 | No |
| 39 | TBRG4 | transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:HGNC:17443] | 5299 | 0.188 | 0.5520 | No |
| 40 | HSPE1 | heat shock protein family E (Hsp10) member 1 [Source:HGNC Symbol;Acc:HGNC:5269] | 5800 | 0.117 | 0.5401 | No |
| 41 | TMEM97 | transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] | 6667 | 0.001 | 0.5167 | No |
| 42 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 28040 | -0.066 | -0.0594 | No |
| 43 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 29035 | -0.185 | -0.0837 | No |
| 44 | PRMT3 | protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163] | 29556 | -0.246 | -0.0944 | No |
| 45 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 30547 | -0.374 | -0.1159 | No |
| 46 | SUPV3L1 | Suv3 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:11471] | 31100 | -0.455 | -0.1245 | No |
| 47 | TFB2M | transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:18559] | 31538 | -0.528 | -0.1290 | No |
| 48 | SLC29A2 | solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004] | 32572 | -0.728 | -0.1468 | No |
| 49 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34419 | -1.276 | -0.1790 | No |
| 50 | CDK4 | cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773] | 34498 | -1.311 | -0.1630 | No |
| 51 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34760 | -1.422 | -0.1503 | No |
| 52 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35100 | -1.565 | -0.1378 | No |
| 53 | UNG | uracil DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572] | 35303 | -1.677 | -0.1201 | No |
| 54 | EXOSC5 | exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662] | 35339 | -1.693 | -0.0976 | No |
| 55 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35939 | -2.080 | -0.0850 | No |
| 56 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 36292 | -2.399 | -0.0612 | No |
| 57 | MAP3K6 | mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858] | 36609 | -2.788 | -0.0312 | No |
| 58 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36793 | -3.189 | 0.0080 | No |
