Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_GAQ_versus_KO_NA.greenbergcls.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | 0.46567255 |
| Normalized Enrichment Score (NES) | 1.0667088 |
| Nominal p-value | 0.2857143 |
| FDR q-value | 0.3185147 |
| FWER p-Value | 0.777 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 109 | 3.467 | 0.0608 | Yes |
| 2 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 128 | 3.319 | 0.1214 | Yes |
| 3 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 138 | 3.244 | 0.1808 | Yes |
| 4 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 212 | 2.871 | 0.2317 | Yes |
| 5 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 222 | 2.805 | 0.2831 | Yes |
| 6 | SRXN1 | sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132] | 349 | 2.398 | 0.3238 | Yes |
| 7 | SELENOS | selenoprotein S [Source:HGNC Symbol;Acc:HGNC:30396] | 538 | 1.989 | 0.3553 | Yes |
| 8 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 673 | 1.758 | 0.3840 | Yes |
| 9 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 918 | 1.487 | 0.4048 | Yes |
| 10 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1303 | 1.198 | 0.4165 | Yes |
| 11 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1402 | 1.156 | 0.4351 | Yes |
| 12 | EGLN2 | egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660] | 1466 | 1.128 | 0.4541 | Yes |
| 13 | SCAF4 | SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304] | 2166 | 0.830 | 0.4505 | Yes |
| 14 | MSRA | methionine sulfoxide reductase A [Source:HGNC Symbol;Acc:HGNC:7377] | 2443 | 0.743 | 0.4568 | Yes |
| 15 | G6PD | glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] | 2587 | 0.694 | 0.4657 | Yes |
| 16 | LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:HGNC Symbol;Acc:HGNC:17955] | 3188 | 0.553 | 0.4597 | No |
| 17 | HHEX | hematopoietically expressed homeobox [Source:HGNC Symbol;Acc:HGNC:4901] | 3645 | 0.465 | 0.4559 | No |
| 18 | GSR | glutathione-disulfide reductase [Source:HGNC Symbol;Acc:HGNC:4623] | 3827 | 0.433 | 0.4590 | No |
| 19 | ATOX1 | antioxidant 1 copper chaperone [Source:HGNC Symbol;Acc:HGNC:798] | 4770 | 0.269 | 0.4385 | No |
| 20 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434] | 6106 | 0.080 | 0.4039 | No |
| 21 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9767 | 0.000 | 0.3051 | No |
| 22 | MGST1 | microsomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNC:7061] | 12072 | 0.000 | 0.2429 | No |
| 23 | IPCEF1 | interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204] | 17949 | 0.000 | 0.0843 | No |
| 24 | MPO | myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218] | 19010 | 0.000 | 0.0557 | No |
| 25 | NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4 [Source:HGNC Symbol;Acc:HGNC:7699] | 22917 | 0.000 | -0.0498 | No |
| 26 | FTL | ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999] | 27726 | -0.029 | -0.1790 | No |
| 27 | GLRX2 | glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065] | 28153 | -0.079 | -0.1891 | No |
| 28 | PRDX2 | peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353] | 28246 | -0.090 | -0.1899 | No |
| 29 | TXNRD2 | thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155] | 28735 | -0.147 | -0.2004 | No |
| 30 | STK25 | serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404] | 28989 | -0.176 | -0.2040 | No |
| 31 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29209 | -0.205 | -0.2061 | No |
| 32 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 29370 | -0.225 | -0.2063 | No |
| 33 | PDLIM1 | PDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067] | 29523 | -0.243 | -0.2059 | No |
| 34 | OXSR1 | oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508] | 31137 | -0.459 | -0.2410 | No |
| 35 | PTPA | protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308] | 32004 | -0.609 | -0.2532 | No |
| 36 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 32075 | -0.626 | -0.2436 | No |
| 37 | FES | FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657] | 33005 | -0.832 | -0.2534 | No |
| 38 | GCLC | glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311] | 33059 | -0.848 | -0.2392 | No |
| 39 | HMOX2 | heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014] | 33128 | -0.865 | -0.2251 | No |
| 40 | NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690] | 33744 | -1.046 | -0.2225 | No |
| 41 | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708] | 33841 | -1.077 | -0.2052 | No |
| 42 | PRDX6 | peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753] | 34019 | -1.135 | -0.1891 | No |
| 43 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35048 | -1.539 | -0.1886 | No |
| 44 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 35099 | -1.564 | -0.1611 | No |
| 45 | PRNP | prion protein [Source:HGNC Symbol;Acc:HGNC:9449] | 35164 | -1.596 | -0.1335 | No |
| 46 | PFKP | phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878] | 35621 | -1.848 | -0.1118 | No |
| 47 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 36354 | -2.464 | -0.0862 | No |
| 48 | CDKN2D | cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790] | 36515 | -2.664 | -0.0416 | No |
| 49 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36767 | -3.101 | 0.0087 | No |
