Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | CHR17Q12 |
| Enrichment Score (ES) | 0.48865014 |
| Normalized Enrichment Score (NES) | 1.2851272 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.41644067 |
| FWER p-Value | 0.847 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.991 | 0.0528 | Yes |
| 2 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 36 | 4.695 | 0.1018 | Yes |
| 3 | SLFN5 | schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286] | 55 | 4.457 | 0.1485 | Yes |
| 4 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 80 | 4.213 | 0.1925 | Yes |
| 5 | SLFN11 | schlafen family member 11 [Source:HGNC Symbol;Acc:HGNC:26633] | 146 | 3.718 | 0.2302 | Yes |
| 6 | SLFN13 | schlafen family member 13 [Source:HGNC Symbol;Acc:HGNC:26481] | 195 | 3.422 | 0.2652 | Yes |
| 7 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 235 | 3.171 | 0.2978 | Yes |
| 8 | RFFL | ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821] | 463 | 2.381 | 0.3169 | Yes |
| 9 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 551 | 2.174 | 0.3376 | Yes |
| 10 | STARD3 | StAR related lipid transfer domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17579] | 688 | 1.934 | 0.3544 | Yes |
| 11 | CWC25 | CWC25 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:25989] | 993 | 1.553 | 0.3626 | Yes |
| 12 | CDK12 | cyclin dependent kinase 12 [Source:HGNC Symbol;Acc:HGNC:24224] | 1204 | 1.338 | 0.3711 | Yes |
| 13 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 1236 | 1.314 | 0.3842 | Yes |
| 14 | C17orf50 | chromosome 17 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:29581] | 1352 | 1.231 | 0.3942 | Yes |
| 15 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1419 | 1.192 | 0.4050 | Yes |
| 16 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 1631 | 1.072 | 0.4107 | Yes |
| 17 | SRCIN1 | SRC kinase signaling inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:29506] | 1656 | 1.055 | 0.4212 | Yes |
| 18 | NLE1 | notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:19889] | 1742 | 1.007 | 0.4296 | Yes |
| 19 | SNORD7 | small nucleolar RNA, C/D box 7 [Source:HGNC Symbol;Acc:HGNC:32704] | 1811 | 0.975 | 0.4381 | Yes |
| 20 | MIEN1 | migration and invasion enhancer 1 [Source:HGNC Symbol;Acc:HGNC:28230] | 1940 | 0.926 | 0.4444 | Yes |
| 21 | UNC45B | unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:HGNC:14304] | 1969 | 0.912 | 0.4534 | Yes |
| 22 | YWHAEP7 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:49437] | 2045 | 0.882 | 0.4607 | Yes |
| 23 | ZNF830 | zinc finger protein 830 [Source:HGNC Symbol;Acc:HGNC:28291] | 2296 | 0.780 | 0.4622 | Yes |
| 24 | PEX12 | peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854] | 2322 | 0.772 | 0.4697 | Yes |
| 25 | HEATR9 | HEAT repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:26548] | 2397 | 0.750 | 0.4756 | Yes |
| 26 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 2490 | 0.716 | 0.4807 | Yes |
| 27 | DHRS11 | dehydrogenase/reductase 11 [Source:HGNC Symbol;Acc:HGNC:28639] | 2750 | 0.635 | 0.4805 | Yes |
| 28 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 2989 | 0.567 | 0.4800 | Yes |
| 29 | AP2B1 | adaptor related protein complex 2 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:563] | 3220 | 0.512 | 0.4792 | Yes |
| 30 | PIGW | phosphatidylinositol glycan anchor biosynthesis class W [Source:HGNC Symbol;Acc:HGNC:23213] | 3369 | 0.480 | 0.4803 | Yes |
| 31 | E2F3P1 | E2F transcription factor 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:3116] | 3501 | 0.453 | 0.4816 | Yes |
| 32 | PSMB3 | proteasome 20S subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:9540] | 3502 | 0.452 | 0.4864 | Yes |
| 33 | ZNHIT3 | zinc finger HIT-type containing 3 [Source:HGNC Symbol;Acc:HGNC:12309] | 3637 | 0.425 | 0.4872 | Yes |
| 34 | TCAP | titin-cap [Source:HGNC Symbol;Acc:HGNC:11610] | 3744 | 0.403 | 0.4887 | Yes |
| 35 | MYO19 | myosin XIX [Source:HGNC Symbol;Acc:HGNC:26234] | 4130 | 0.334 | 0.4818 | No |
| 36 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4325 | 0.292 | 0.4796 | No |
| 37 | FBXO47 | F-box protein 47 [Source:HGNC Symbol;Acc:HGNC:31969] | 4971 | 0.187 | 0.4642 | No |
| 38 | LIG3 | DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600] | 5034 | 0.178 | 0.4644 | No |
| 39 | GGNBP2 | gametogenetin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19357] | 6008 | 0.032 | 0.4384 | No |
| 40 | AATF | apoptosis antagonizing transcription factor [Source:HGNC Symbol;Acc:HGNC:19235] | 6027 | 0.029 | 0.4382 | No |
| 41 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6232 | 0.000 | 0.4327 | No |
| 42 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6233 | 0.000 | 0.4327 | No |
| 43 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6234 | 0.000 | 0.4327 | No |
| 44 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6254 | 0.000 | 0.4322 | No |
| 45 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6257 | 0.000 | 0.4321 | No |
| 46 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6259 | 0.000 | 0.4321 | No |
| 47 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6263 | 0.000 | 0.4320 | No |
| 48 | TBC1D3 | TBC1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:19031] | 7401 | 0.000 | 0.4012 | No |
| 49 | LYZL6 | lysozyme like 6 [Source:HGNC Symbol;Acc:HGNC:29614] | 7704 | 0.000 | 0.3931 | No |
| 50 | ASIC2 | acid sensing ion channel subunit 2 [Source:HGNC Symbol;Acc:HGNC:99] | 7756 | 0.000 | 0.3917 | No |
| 51 | MIR2909 | microRNA 2909 [Source:HGNC Symbol;Acc:HGNC:38372] | 8922 | 0.000 | 0.3602 | No |
| 52 | RASL10B | RAS like family 10 member B [Source:HGNC Symbol;Acc:HGNC:30295] | 9667 | 0.000 | 0.3400 | No |
| 53 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 9730 | 0.000 | 0.3384 | No |
| 54 | AA06 | uncharacterized LOC100506677 [Source:NCBI gene (formerly Entrezgene);Acc:100506677] | 10028 | 0.000 | 0.3303 | No |
| 55 | PNMT | phenylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:9160] | 10409 | 0.000 | 0.3200 | No |
| 56 | C17orf78 | chromosome 17 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:26831] | 11577 | 0.000 | 0.2885 | No |
| 57 | C17orf98 | chromosome 17 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:34492] | 11599 | 0.000 | 0.2879 | No |
| 58 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 11834 | 0.000 | 0.2816 | No |
| 59 | SNHG30 | small nucleolar RNA host gene 30 [Source:HGNC Symbol;Acc:HGNC:52836] | 12033 | 0.000 | 0.2762 | No |
| 60 | SLFN14 | schlafen family member 14 [Source:HGNC Symbol;Acc:HGNC:32689] | 12092 | 0.000 | 0.2746 | No |
| 61 | LHX1 | LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6593] | 12291 | 0.000 | 0.2693 | No |
| 62 | RNU6-1192P | RNA, U6 small nuclear 1192, pseudogene [Source:HGNC Symbol;Acc:HGNC:48155] | 12822 | 0.000 | 0.2549 | No |
| 63 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14647 | 0.000 | 0.2056 | No |
| 64 | SLC35G3 | solute carrier family 35 member G3 [Source:HGNC Symbol;Acc:HGNC:26848] | 15890 | 0.000 | 0.1720 | No |
| 65 | RN7SL301P | RNA, 7SL, cytoplasmic 301, pseudogene [Source:HGNC Symbol;Acc:HGNC:46317] | 15966 | 0.000 | 0.1700 | No |
| 66 | SNORA21 | small nucleolar RNA, H/ACA box 21 [Source:HGNC Symbol;Acc:HGNC:32611] | 16042 | 0.000 | 0.1679 | No |
| 67 | C17orf102 | chromosome 17 open reading frame 102 [Source:HGNC Symbol;Acc:HGNC:34412] | 16523 | 0.000 | 0.1549 | No |
| 68 | RNU6-866P | RNA, U6 small nuclear 866, pseudogene [Source:HGNC Symbol;Acc:HGNC:47829] | 17008 | 0.000 | 0.1418 | No |
| 69 | RNA5SP440 | RNA, 5S ribosomal pseudogene 440 [Source:HGNC Symbol;Acc:HGNC:43340] | 17227 | 0.000 | 0.1359 | No |
| 70 | RNA5SP439 | RNA, 5S ribosomal pseudogene 439 [Source:HGNC Symbol;Acc:HGNC:43339] | 17262 | 0.000 | 0.1350 | No |
| 71 | RNA5SP438 | RNA, 5S ribosomal pseudogene 438 [Source:HGNC Symbol;Acc:HGNC:43338] | 17263 | 0.000 | 0.1350 | No |
| 72 | CCL15-CCL14 | CCL15-CCL14 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44436] | 17376 | 0.000 | 0.1320 | No |
| 73 | HNF1B | HNF1 homeobox B [Source:HGNC Symbol;Acc:HGNC:11630] | 17534 | 0.000 | 0.1277 | No |
| 74 | PPP1R1B | protein phosphatase 1 regulatory inhibitor subunit 1B [Source:HGNC Symbol;Acc:HGNC:9287] | 17575 | 0.000 | 0.1267 | No |
| 75 | LRRC37A9P | leucine rich repeat containing 37 member A9, pseudogene [Source:HGNC Symbol;Acc:HGNC:43813] | 17619 | 0.000 | 0.1255 | No |
| 76 | RNU6-489P | RNA, U6 small nuclear 489, pseudogene [Source:HGNC Symbol;Acc:HGNC:47452] | 18400 | 0.000 | 0.1044 | No |
| 77 | RNU6-233P | RNA, U6 small nuclear 233, pseudogene [Source:HGNC Symbol;Acc:HGNC:47196] | 18802 | 0.000 | 0.0935 | No |
| 78 | NEUROD2 | neuronal differentiation 2 [Source:HGNC Symbol;Acc:HGNC:7763] | 19148 | 0.000 | 0.0842 | No |
| 79 | LINC01989 | long intergenic non-protein coding RNA 1989 [Source:HGNC Symbol;Acc:HGNC:52821] | 20274 | 0.000 | 0.0538 | No |
| 80 | LINC02079 | long intergenic non-protein coding RNA 2079 [Source:HGNC Symbol;Acc:HGNC:52927] | 21471 | 0.000 | 0.0214 | No |
| 81 | TBC1D3K | TBC1 domain family member 3K [Source:HGNC Symbol;Acc:HGNC:51245] | 22097 | 0.000 | 0.0045 | No |
| 82 | TBC1D3L | TBC1 domain family member 3L [Source:HGNC Symbol;Acc:HGNC:51246] | 22098 | 0.000 | 0.0045 | No |
| 83 | TBC1D3B | TBC1 domain family member 3B [Source:HGNC Symbol;Acc:HGNC:27011] | 22104 | 0.000 | 0.0044 | No |
| 84 | TBC1D3E | TBC1 domain family member 3E [Source:HGNC Symbol;Acc:HGNC:27071] | 22106 | 0.000 | 0.0043 | No |
| 85 | TBC1D3F | TBC1 domain family member 3F [Source:HGNC Symbol;Acc:HGNC:18257] | 22107 | 0.000 | 0.0043 | No |
| 86 | TBC1D3C | TBC1 domain family member 3C [Source:HGNC Symbol;Acc:HGNC:24889] | 22109 | 0.000 | 0.0043 | No |
| 87 | TBC1D3D | TBC1 domain family member 3D [Source:HGNC Symbol;Acc:HGNC:28944] | 22110 | 0.000 | 0.0043 | No |
| 88 | TBC1D3I | TBC1 domain family member 3I [Source:HGNC Symbol;Acc:HGNC:32709] | 22111 | 0.000 | 0.0043 | No |
| 89 | TBC1D3J | TBC1 domain family member 3J [Source:HGNC Symbol;Acc:HGNC:51247] | 22113 | 0.000 | 0.0043 | No |
| 90 | TBC1D3G | TBC1 domain family member 3G [Source:HGNC Symbol;Acc:HGNC:29860] | 22115 | 0.000 | 0.0043 | No |
| 91 | TBC1D3H | TBC1 domain family member 3H [Source:HGNC Symbol;Acc:HGNC:30708] | 22116 | 0.000 | 0.0043 | No |
| 92 | TMEM132E | transmembrane protein 132E [Source:HGNC Symbol;Acc:HGNC:26991] | 22344 | 0.000 | -0.0019 | No |
| 93 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22723 | 0.000 | -0.0121 | No |
| 94 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22725 | 0.000 | -0.0121 | No |
| 95 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 22733 | 0.000 | -0.0123 | No |
| 96 | FNDC8 | fibronectin type III domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25286] | 25514 | 0.000 | -0.0875 | No |
| 97 | RNU6-840P | RNA, U6 small nuclear 840, pseudogene [Source:HGNC Symbol;Acc:HGNC:47803] | 25617 | 0.000 | -0.0903 | No |
| 98 | GAS2L2 | growth arrest specific 2 like 2 [Source:HGNC Symbol;Acc:HGNC:24846] | 26440 | 0.000 | -0.1125 | No |
| 99 | MIR4734 | microRNA 4734 [Source:HGNC Symbol;Acc:HGNC:41572] | 26859 | 0.000 | -0.1239 | No |
| 100 | MIR4726 | microRNA 4726 [Source:HGNC Symbol;Acc:HGNC:41722] | 26878 | 0.000 | -0.1243 | No |
| 101 | MIR4728 | microRNA 4728 [Source:HGNC Symbol;Acc:HGNC:41632] | 26881 | 0.000 | -0.1244 | No |
| 102 | MIR4727 | microRNA 4727 [Source:HGNC Symbol;Acc:HGNC:41709] | 26882 | 0.000 | -0.1244 | No |
| 103 | LRRC37A11P | leucine rich repeat containing 37 member A11, pseudogene [Source:HGNC Symbol;Acc:HGNC:43815] | 27134 | 0.000 | -0.1312 | No |
| 104 | SOCS7 | suppressor of cytokine signaling 7 [Source:HGNC Symbol;Acc:HGNC:29846] | 27301 | -0.030 | -0.1354 | No |
| 105 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 27365 | -0.040 | -0.1366 | No |
| 106 | ARL5C | ADP ribosylation factor like GTPase 5C [Source:HGNC Symbol;Acc:HGNC:31111] | 28129 | -0.131 | -0.1559 | No |
| 107 | RPL23 | ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316] | 28160 | -0.135 | -0.1553 | No |
| 108 | RPL19 | ribosomal protein L19 [Source:HGNC Symbol;Acc:HGNC:10312] | 28545 | -0.188 | -0.1637 | No |
| 109 | MLLT6 | MLLT6, PHD finger containing [Source:HGNC Symbol;Acc:HGNC:7138] | 29443 | -0.306 | -0.1847 | No |
| 110 | PGAP3 | post-GPI attachment to proteins phospholipase 3 [Source:HGNC Symbol;Acc:HGNC:23719] | 29539 | -0.317 | -0.1839 | No |
| 111 | TOMM20P2 | TOMM20 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:50519] | 30078 | -0.391 | -0.1943 | No |
| 112 | ARHGAP23 | Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293] | 30648 | -0.476 | -0.2047 | No |
| 113 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 31564 | -0.630 | -0.2227 | No |
| 114 | EPOP | elongin BC and polycomb repressive complex 2 associated protein [Source:HGNC Symbol;Acc:HGNC:34493] | 31673 | -0.650 | -0.2188 | No |
| 115 | SYNRG | synergin gamma [Source:HGNC Symbol;Acc:HGNC:557] | 32009 | -0.732 | -0.2201 | No |
| 116 | PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:8998] | 32419 | -0.830 | -0.2223 | No |
| 117 | MMP28 | matrix metallopeptidase 28 [Source:HGNC Symbol;Acc:HGNC:14366] | 33451 | -1.124 | -0.2383 | No |
| 118 | CISD3 | CDGSH iron sulfur domain 3 [Source:HGNC Symbol;Acc:HGNC:27578] | 34061 | -1.332 | -0.2407 | No |
| 119 | HMGB1P24 | high mobility group box 1 pseudogene 24 [Source:HGNC Symbol;Acc:HGNC:39115] | 34088 | -1.342 | -0.2271 | No |
| 120 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 34135 | -1.361 | -0.2140 | No |
| 121 | ACACA | acetyl-CoA carboxylase alpha [Source:HGNC Symbol;Acc:HGNC:84] | 34335 | -1.447 | -0.2040 | No |
| 122 | LINC00672 | long intergenic non-protein coding RNA 672 [Source:HGNC Symbol;Acc:HGNC:44353] | 34568 | -1.541 | -0.1939 | No |
| 123 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:1401] | 34581 | -1.545 | -0.1779 | No |
| 124 | MRM1 | mitochondrial rRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26202] | 34889 | -1.684 | -0.1683 | No |
| 125 | DDX52 | DExD-box helicase 52 [Source:HGNC Symbol;Acc:HGNC:20038] | 35114 | -1.806 | -0.1552 | No |
| 126 | GPR179 | G protein-coupled receptor 179 [Source:HGNC Symbol;Acc:HGNC:31371] | 35546 | -2.080 | -0.1448 | No |
| 127 | RDM1 | RAD52 motif containing 1 [Source:HGNC Symbol;Acc:HGNC:19950] | 35836 | -2.299 | -0.1283 | No |
| 128 | TADA2A | transcriptional adaptor 2A [Source:HGNC Symbol;Acc:HGNC:11531] | 36126 | -2.573 | -0.1088 | No |
| 129 | STAC2 | SH3 and cysteine rich domain 2 [Source:HGNC Symbol;Acc:HGNC:23990] | 36345 | -2.850 | -0.0845 | No |
| 130 | PLXDC1 | plexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20945] | 36486 | -3.030 | -0.0562 | No |
| 131 | FBXL20 | F-box and leucine rich repeat protein 20 [Source:HGNC Symbol;Acc:HGNC:24679] | 36725 | -3.405 | -0.0265 | No |
| 132 | PCGF2 | polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929] | 36742 | -3.428 | 0.0094 | No |
