Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CROONQUIST_IL6_DEPRIVATION_DN |
| Enrichment Score (ES) | -0.82744247 |
| Normalized Enrichment Score (NES) | -1.7099546 |
| Nominal p-value | 0.0 |
| FDR q-value | 5.7630077E-5 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 185 | 3.492 | 0.0120 | No |
| 2 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 657 | 1.983 | 0.0089 | No |
| 3 | ABHD5 | abhydrolase domain containing 5, lysophosphatidic acid acyltransferase [Source:HGNC Symbol;Acc:HGNC:21396] | 1249 | 1.306 | -0.0008 | No |
| 4 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 1302 | 1.266 | 0.0040 | No |
| 5 | HMGA1 | high mobility group AT-hook 1 [Source:HGNC Symbol;Acc:HGNC:5010] | 1822 | 0.972 | -0.0053 | No |
| 6 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2357 | 0.761 | -0.0161 | No |
| 7 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 3931 | 0.374 | -0.0568 | No |
| 8 | PTPRC | protein tyrosine phosphatase receptor type C [Source:HGNC Symbol;Acc:HGNC:9666] | 4227 | 0.313 | -0.0632 | No |
| 9 | SNRPA1 | small nuclear ribonucleoprotein polypeptide A' [Source:HGNC Symbol;Acc:HGNC:11152] | 5089 | 0.168 | -0.0857 | No |
| 10 | AASS | aminoadipate-semialdehyde synthase [Source:HGNC Symbol;Acc:HGNC:17366] | 10310 | 0.000 | -0.2268 | No |
| 11 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12425 | 0.000 | -0.2839 | No |
| 12 | FRZB | frizzled related protein [Source:HGNC Symbol;Acc:HGNC:3959] | 16696 | 0.000 | -0.3993 | No |
| 13 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 23814 | 0.000 | -0.5917 | No |
| 14 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25820 | 0.000 | -0.6459 | No |
| 15 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 28511 | -0.184 | -0.7177 | No |
| 16 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 29469 | -0.309 | -0.7421 | No |
| 17 | CDC25A | cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725] | 30018 | -0.381 | -0.7550 | No |
| 18 | H2BC11 | H2B clustered histone 11 [Source:HGNC Symbol;Acc:HGNC:4761] | 30214 | -0.410 | -0.7583 | No |
| 19 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 30485 | -0.450 | -0.7634 | No |
| 20 | GMPS | guanine monophosphate synthase [Source:HGNC Symbol;Acc:HGNC:4378] | 31432 | -0.604 | -0.7861 | No |
| 21 | ITM2A | integral membrane protein 2A [Source:HGNC Symbol;Acc:HGNC:6173] | 31857 | -0.691 | -0.7942 | No |
| 22 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32217 | -0.779 | -0.8001 | No |
| 23 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32921 | -0.962 | -0.8144 | No |
| 24 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8165 | No |
| 25 | SEPHS1 | selenophosphate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:19685] | 33199 | -1.044 | -0.8117 | No |
| 26 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 33539 | -1.153 | -0.8153 | No |
| 27 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.8120 | No |
| 28 | SPOUT1 | SPOUT domain containing methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26933] | 34203 | -1.392 | -0.8207 | Yes |
| 29 | CHAF1A | chromatin assembly factor 1 subunit A [Source:HGNC Symbol;Acc:HGNC:1910] | 34368 | -1.462 | -0.8180 | Yes |
| 30 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 34511 | -1.519 | -0.8145 | Yes |
| 31 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.8083 | Yes |
| 32 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34573 | -1.544 | -0.8011 | Yes |
| 33 | KNTC1 | kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255] | 34787 | -1.635 | -0.7989 | Yes |
| 34 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 34916 | -1.697 | -0.7942 | Yes |
| 35 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34948 | -1.710 | -0.7867 | Yes |
| 36 | STIL | STIL centriolar assembly protein [Source:HGNC Symbol;Acc:HGNC:10879] | 35038 | -1.759 | -0.7806 | Yes |
| 37 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35107 | -1.803 | -0.7736 | Yes |
| 38 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35218 | -1.870 | -0.7675 | Yes |
| 39 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35306 | -1.922 | -0.7605 | Yes |
| 40 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 35322 | -1.930 | -0.7516 | Yes |
| 41 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35430 | -1.996 | -0.7448 | Yes |
| 42 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35462 | -2.024 | -0.7358 | Yes |
| 43 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35526 | -2.066 | -0.7274 | Yes |
| 44 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35565 | -2.097 | -0.7183 | Yes |
| 45 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35590 | -2.112 | -0.7087 | Yes |
| 46 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35601 | -2.118 | -0.6986 | Yes |
| 47 | BRCA1 | BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100] | 35622 | -2.133 | -0.6888 | Yes |
| 48 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35623 | -2.133 | -0.6785 | Yes |
| 49 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35629 | -2.136 | -0.6682 | Yes |
| 50 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35715 | -2.202 | -0.6598 | Yes |
| 51 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35976 | -2.431 | -0.6550 | Yes |
| 52 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35996 | -2.449 | -0.6437 | Yes |
| 53 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 36013 | -2.468 | -0.6321 | Yes |
| 54 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36050 | -2.499 | -0.6209 | Yes |
| 55 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 36054 | -2.502 | -0.6089 | Yes |
| 56 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 36180 | -2.639 | -0.5994 | Yes |
| 57 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 36181 | -2.640 | -0.5866 | Yes |
| 58 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.5749 | Yes |
| 59 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36254 | -2.721 | -0.5622 | Yes |
| 60 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36278 | -2.752 | -0.5495 | Yes |
| 61 | GALE | UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116] | 36374 | -2.879 | -0.5380 | Yes |
| 62 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36404 | -2.906 | -0.5247 | Yes |
| 63 | TRAIP | TRAF interacting protein [Source:HGNC Symbol;Acc:HGNC:30764] | 36414 | -2.913 | -0.5108 | Yes |
| 64 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36416 | -2.915 | -0.4967 | Yes |
| 65 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36438 | -2.948 | -0.4829 | Yes |
| 66 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36448 | -2.956 | -0.4688 | Yes |
| 67 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.4546 | Yes |
| 68 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 36487 | -3.032 | -0.4406 | Yes |
| 69 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36506 | -3.053 | -0.4263 | Yes |
| 70 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 36527 | -3.075 | -0.4119 | Yes |
| 71 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36549 | -3.110 | -0.3973 | Yes |
| 72 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.3831 | Yes |
| 73 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.3679 | Yes |
| 74 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36620 | -3.234 | -0.3522 | Yes |
| 75 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.3370 | Yes |
| 76 | GALK1 | galactokinase 1 [Source:HGNC Symbol;Acc:HGNC:4118] | 36654 | -3.289 | -0.3212 | Yes |
| 77 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36674 | -3.329 | -0.3055 | Yes |
| 78 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36677 | -3.335 | -0.2894 | Yes |
| 79 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36684 | -3.340 | -0.2733 | Yes |
| 80 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36693 | -3.364 | -0.2572 | Yes |
| 81 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36704 | -3.383 | -0.2410 | Yes |
| 82 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36710 | -3.387 | -0.2247 | Yes |
| 83 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36729 | -3.410 | -0.2086 | Yes |
| 84 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36732 | -3.413 | -0.1921 | Yes |
| 85 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36749 | -3.440 | -0.1758 | Yes |
| 86 | PTP4A3 | protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636] | 36792 | -3.522 | -0.1598 | Yes |
| 87 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36797 | -3.534 | -0.1428 | Yes |
| 88 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36809 | -3.551 | -0.1258 | Yes |
| 89 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36819 | -3.570 | -0.1087 | Yes |
| 90 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.0915 | Yes |
| 91 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36871 | -3.689 | -0.0747 | Yes |
| 92 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36874 | -3.693 | -0.0568 | Yes |
| 93 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.0391 | Yes |
| 94 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37042 | -4.354 | -0.0214 | Yes |
| 95 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37079 | -4.675 | 0.0003 | Yes |
