Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CROONQUIST_NRAS_SIGNALING_DN |
| Enrichment Score (ES) | -0.85821 |
| Normalized Enrichment Score (NES) | -1.7214841 |
| Nominal p-value | 0.0 |
| FDR q-value | 7.334737E-5 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 1302 | 1.266 | -0.0273 | No |
| 2 | GNAI1 | G protein subunit alpha i1 [Source:HGNC Symbol;Acc:HGNC:4384] | 1378 | 1.217 | -0.0218 | No |
| 3 | HMGA1 | high mobility group AT-hook 1 [Source:HGNC Symbol;Acc:HGNC:5010] | 1822 | 0.972 | -0.0278 | No |
| 4 | EIF5 | eukaryotic translation initiation factor 5 [Source:HGNC Symbol;Acc:HGNC:3299] | 2204 | 0.814 | -0.0330 | No |
| 5 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 3931 | 0.374 | -0.0774 | No |
| 6 | SNRPA1 | small nuclear ribonucleoprotein polypeptide A' [Source:HGNC Symbol;Acc:HGNC:11152] | 5089 | 0.168 | -0.1076 | No |
| 7 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12425 | 0.000 | -0.3057 | No |
| 8 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 23814 | 0.000 | -0.6133 | No |
| 9 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25820 | 0.000 | -0.6675 | No |
| 10 | PLOD2 | procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [Source:HGNC Symbol;Acc:HGNC:9082] | 30517 | -0.456 | -0.7915 | No |
| 11 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32217 | -0.779 | -0.8326 | No |
| 12 | CSE1L | chromosome segregation 1 like [Source:HGNC Symbol;Acc:HGNC:2431] | 32517 | -0.856 | -0.8354 | No |
| 13 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8470 | No |
| 14 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 33539 | -1.153 | -0.8493 | No |
| 15 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.8444 | No |
| 16 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 34141 | -1.363 | -0.8498 | Yes |
| 17 | CHAF1A | chromatin assembly factor 1 subunit A [Source:HGNC Symbol;Acc:HGNC:1910] | 34368 | -1.462 | -0.8468 | Yes |
| 18 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.8425 | Yes |
| 19 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34948 | -1.710 | -0.8424 | Yes |
| 20 | POLD3 | DNA polymerase delta 3, accessory subunit [Source:HGNC Symbol;Acc:HGNC:20932] | 35017 | -1.748 | -0.8334 | Yes |
| 21 | STIL | STIL centriolar assembly protein [Source:HGNC Symbol;Acc:HGNC:10879] | 35038 | -1.759 | -0.8231 | Yes |
| 22 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35107 | -1.803 | -0.8137 | Yes |
| 23 | CDC25C | cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727] | 35141 | -1.826 | -0.8033 | Yes |
| 24 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35218 | -1.870 | -0.7938 | Yes |
| 25 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35306 | -1.922 | -0.7843 | Yes |
| 26 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35430 | -1.996 | -0.7753 | Yes |
| 27 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35462 | -2.024 | -0.7636 | Yes |
| 28 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35526 | -2.066 | -0.7525 | Yes |
| 29 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35590 | -2.112 | -0.7411 | Yes |
| 30 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35601 | -2.118 | -0.7283 | Yes |
| 31 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35623 | -2.133 | -0.7157 | Yes |
| 32 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35629 | -2.136 | -0.7026 | Yes |
| 33 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35715 | -2.202 | -0.6913 | Yes |
| 34 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35976 | -2.431 | -0.6833 | Yes |
| 35 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35996 | -2.449 | -0.6686 | Yes |
| 36 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 36013 | -2.468 | -0.6538 | Yes |
| 37 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 36054 | -2.502 | -0.6394 | Yes |
| 38 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 36180 | -2.639 | -0.6264 | Yes |
| 39 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 36181 | -2.640 | -0.6101 | Yes |
| 40 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 36216 | -2.675 | -0.5945 | Yes |
| 41 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.5782 | Yes |
| 42 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36278 | -2.752 | -0.5624 | Yes |
| 43 | GALE | UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116] | 36374 | -2.879 | -0.5472 | Yes |
| 44 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36404 | -2.906 | -0.5300 | Yes |
| 45 | TRAIP | TRAF interacting protein [Source:HGNC Symbol;Acc:HGNC:30764] | 36414 | -2.913 | -0.5122 | Yes |
| 46 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36438 | -2.948 | -0.4946 | Yes |
| 47 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.4767 | Yes |
| 48 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 36487 | -3.032 | -0.4587 | Yes |
| 49 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36533 | -3.091 | -0.4408 | Yes |
| 50 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36549 | -3.110 | -0.4220 | Yes |
| 51 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.4035 | Yes |
| 52 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.3841 | Yes |
| 53 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36620 | -3.234 | -0.3641 | Yes |
| 54 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.3445 | Yes |
| 55 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36677 | -3.335 | -0.3246 | Yes |
| 56 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36684 | -3.340 | -0.3041 | Yes |
| 57 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36693 | -3.364 | -0.2835 | Yes |
| 58 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36710 | -3.387 | -0.2630 | Yes |
| 59 | CHEK2 | checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627] | 36718 | -3.398 | -0.2422 | Yes |
| 60 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36729 | -3.410 | -0.2214 | Yes |
| 61 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36732 | -3.413 | -0.2003 | Yes |
| 62 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36749 | -3.440 | -0.1795 | Yes |
| 63 | PTP4A3 | protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636] | 36792 | -3.522 | -0.1588 | Yes |
| 64 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36797 | -3.534 | -0.1371 | Yes |
| 65 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36819 | -3.570 | -0.1155 | Yes |
| 66 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.0936 | Yes |
| 67 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36871 | -3.689 | -0.0718 | Yes |
| 68 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36874 | -3.693 | -0.0490 | Yes |
| 69 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 37016 | -4.184 | -0.0269 | Yes |
| 70 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37079 | -4.675 | 0.0003 | Yes |
