Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN |
| Enrichment Score (ES) | 0.87714326 |
| Normalized Enrichment Score (NES) | 2.163 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.995 | 0.0224 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.991 | 0.0447 | Yes |
| 3 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 6 | 4.961 | 0.0670 | Yes |
| 4 | ACOD1 | aconitate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:33904] | 7 | 4.955 | 0.0892 | Yes |
| 5 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 8 | 4.953 | 0.1114 | Yes |
| 6 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 10 | 4.929 | 0.1335 | Yes |
| 7 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 27 | 4.773 | 0.1545 | Yes |
| 8 | PHLDA1 | pleckstrin homology like domain family A member 1 [Source:HGNC Symbol;Acc:HGNC:8933] | 33 | 4.755 | 0.1757 | Yes |
| 9 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 34 | 4.731 | 0.1969 | Yes |
| 10 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 42 | 4.653 | 0.2176 | Yes |
| 11 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 50 | 4.531 | 0.2378 | Yes |
| 12 | SOCS3 | suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391] | 52 | 4.513 | 0.2580 | Yes |
| 13 | TRAF1 | TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031] | 61 | 4.416 | 0.2776 | Yes |
| 14 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 70 | 4.306 | 0.2967 | Yes |
| 15 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 73 | 4.254 | 0.3157 | Yes |
| 16 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 80 | 4.213 | 0.3345 | Yes |
| 17 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 81 | 4.209 | 0.3533 | Yes |
| 18 | ITGA5 | integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141] | 87 | 4.155 | 0.3718 | Yes |
| 19 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 96 | 4.072 | 0.3899 | Yes |
| 20 | ADORA2B | adenosine A2b receptor [Source:HGNC Symbol;Acc:HGNC:264] | 97 | 4.067 | 0.4082 | Yes |
| 21 | PIM1 | Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986] | 106 | 4.021 | 0.4260 | Yes |
| 22 | CD83 | CD83 molecule [Source:HGNC Symbol;Acc:HGNC:1703] | 107 | 4.006 | 0.4440 | Yes |
| 23 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 114 | 3.942 | 0.4615 | Yes |
| 24 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 124 | 3.892 | 0.4787 | Yes |
| 25 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 143 | 3.726 | 0.4949 | Yes |
| 26 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 156 | 3.677 | 0.5111 | Yes |
| 27 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 161 | 3.646 | 0.5274 | Yes |
| 28 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 166 | 3.616 | 0.5435 | Yes |
| 29 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 173 | 3.588 | 0.5594 | Yes |
| 30 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 185 | 3.492 | 0.5748 | Yes |
| 31 | PDLIM7 | PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958] | 202 | 3.388 | 0.5896 | Yes |
| 32 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 216 | 3.268 | 0.6039 | Yes |
| 33 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 228 | 3.201 | 0.6179 | Yes |
| 34 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 232 | 3.191 | 0.6322 | Yes |
| 35 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 234 | 3.182 | 0.6464 | Yes |
| 36 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 235 | 3.171 | 0.6606 | Yes |
| 37 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 238 | 3.159 | 0.6748 | Yes |
| 38 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 247 | 3.122 | 0.6886 | Yes |
| 39 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 267 | 3.022 | 0.7016 | Yes |
| 40 | PCDH7 | protocadherin 7 [Source:HGNC Symbol;Acc:HGNC:8659] | 271 | 3.009 | 0.7150 | Yes |
| 41 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 284 | 2.946 | 0.7279 | Yes |
| 42 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 286 | 2.932 | 0.7411 | Yes |
| 43 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 316 | 2.847 | 0.7530 | Yes |
| 44 | ACTG1 | actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144] | 350 | 2.708 | 0.7643 | Yes |
| 45 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 357 | 2.683 | 0.7762 | Yes |
| 46 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 370 | 2.641 | 0.7877 | Yes |
| 47 | BCL2L11 | BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994] | 443 | 2.431 | 0.7967 | Yes |
| 48 | IKBKE | inhibitor of nuclear factor kappa B kinase subunit epsilon [Source:HGNC Symbol;Acc:HGNC:14552] | 454 | 2.405 | 0.8072 | Yes |
| 49 | IL18RAP | interleukin 18 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5989] | 498 | 2.297 | 0.8163 | Yes |
| 50 | SRPRA | SRP receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:11307] | 531 | 2.235 | 0.8255 | Yes |
| 51 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 551 | 2.174 | 0.8347 | Yes |
| 52 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 637 | 2.010 | 0.8414 | Yes |
| 53 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 639 | 2.009 | 0.8504 | Yes |
| 54 | HERPUD1 | homocysteine inducible ER protein with ubiquitin like domain 1 [Source:HGNC Symbol;Acc:HGNC:13744] | 707 | 1.887 | 0.8571 | Yes |
| 55 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 945 | 1.611 | 0.8579 | Yes |
| 56 | RAC2 | Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802] | 1150 | 1.389 | 0.8586 | Yes |
| 57 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1327 | 1.250 | 0.8595 | Yes |
| 58 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 1412 | 1.197 | 0.8626 | Yes |
| 59 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1419 | 1.192 | 0.8678 | Yes |
| 60 | TSC22D1 | TSC22 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:16826] | 1458 | 1.168 | 0.8720 | Yes |
| 61 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 1462 | 1.167 | 0.8771 | Yes |
| 62 | UBB | ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463] | 3080 | 0.545 | 0.8359 | No |
| 63 | CDC42EP4 | CDC42 effector protein 4 [Source:HGNC Symbol;Acc:HGNC:17147] | 3461 | 0.461 | 0.8277 | No |
| 64 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 3515 | 0.450 | 0.8283 | No |
| 65 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 5220 | 0.150 | 0.7829 | No |
| 66 | UBC | ubiquitin C [Source:HGNC Symbol;Acc:HGNC:12468] | 5534 | 0.104 | 0.7749 | No |
| 67 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6263 | 0.000 | 0.7553 | No |
| 68 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8653 | 0.000 | 0.6907 | No |
| 69 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13366 | 0.000 | 0.5634 | No |
| 70 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19345 | 0.000 | 0.4019 | No |
| 71 | PLAUR | plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] | 25337 | 0.000 | 0.2400 | No |
| 72 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 30012 | -0.381 | 0.1154 | No |
| 73 | RREB1 | ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449] | 31881 | -0.698 | 0.0681 | No |
| 74 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 34138 | -1.362 | 0.0132 | No |
| 75 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141] | 34624 | -1.564 | 0.0072 | No |
| 76 | PKM | pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] | 34671 | -1.583 | 0.0130 | No |
| 77 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 35357 | -1.949 | 0.0033 | No |
| 78 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35798 | -2.267 | 0.0015 | No |
| 79 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36406 | -2.907 | -0.0018 | No |
| 80 | SCD | stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] | 37066 | -4.518 | 0.0006 | No |
