Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | GHANDHI_BYSTANDER_IRRADIATION_UP |
| Enrichment Score (ES) | 0.81510335 |
| Normalized Enrichment Score (NES) | 2.0473459 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0929261E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.995 | 0.0445 | Yes |
| 2 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 2 | 4.994 | 0.0891 | Yes |
| 3 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 6 | 4.961 | 0.1333 | Yes |
| 4 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 9 | 4.938 | 0.1773 | Yes |
| 5 | DUSP5 | dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] | 11 | 4.922 | 0.2212 | Yes |
| 6 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 26 | 4.779 | 0.2635 | Yes |
| 7 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 27 | 4.773 | 0.3061 | Yes |
| 8 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 63 | 4.395 | 0.3443 | Yes |
| 9 | CREB5 | cAMP responsive element binding protein 5 [Source:HGNC Symbol;Acc:HGNC:16844] | 64 | 4.383 | 0.3835 | Yes |
| 10 | SLC7A11 | solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059] | 74 | 4.243 | 0.4211 | Yes |
| 11 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 152 | 3.690 | 0.4519 | Yes |
| 12 | OSGIN2 | oxidative stress induced growth inhibitor family member 2 [Source:HGNC Symbol;Acc:HGNC:1355] | 153 | 3.690 | 0.4848 | Yes |
| 13 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 156 | 3.677 | 0.5176 | Yes |
| 14 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 204 | 3.345 | 0.5462 | Yes |
| 15 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 253 | 3.078 | 0.5724 | Yes |
| 16 | SERPINB2 | serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584] | 270 | 3.014 | 0.5988 | Yes |
| 17 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 272 | 3.008 | 0.6256 | Yes |
| 18 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 410 | 2.520 | 0.6444 | Yes |
| 19 | ZC3H12C | zinc finger CCCH-type containing 12C [Source:HGNC Symbol;Acc:HGNC:29362] | 623 | 2.038 | 0.6569 | Yes |
| 20 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 643 | 2.000 | 0.6742 | Yes |
| 21 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 670 | 1.967 | 0.6911 | Yes |
| 22 | TUT7 | terminal uridylyl transferase 7 [Source:HGNC Symbol;Acc:HGNC:25817] | 768 | 1.792 | 0.7044 | Yes |
| 23 | SLC39A14 | solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858] | 781 | 1.775 | 0.7199 | Yes |
| 24 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 849 | 1.693 | 0.7332 | Yes |
| 25 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 945 | 1.611 | 0.7450 | Yes |
| 26 | NAMPTP1 | nicotinamide phosphoribosyltransferase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:17633] | 1292 | 1.276 | 0.7471 | Yes |
| 27 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 1303 | 1.265 | 0.7581 | Yes |
| 28 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 1342 | 1.239 | 0.7681 | Yes |
| 29 | MT1G | metallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399] | 1512 | 1.139 | 0.7737 | Yes |
| 30 | DNAJB4 | DnaJ heat shock protein family (Hsp40) member B4 [Source:HGNC Symbol;Acc:HGNC:14886] | 1536 | 1.125 | 0.7831 | Yes |
| 31 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 1665 | 1.051 | 0.7891 | Yes |
| 32 | GADD45G | growth arrest and DNA damage inducible gamma [Source:HGNC Symbol;Acc:HGNC:4097] | 1961 | 0.918 | 0.7893 | Yes |
| 33 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 2146 | 0.838 | 0.7918 | Yes |
| 34 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2170 | 0.828 | 0.7985 | Yes |
| 35 | MT1E | metallothionein 1E [Source:HGNC Symbol;Acc:HGNC:7397] | 2179 | 0.824 | 0.8057 | Yes |
| 36 | C9orf72 | C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337] | 2252 | 0.797 | 0.8108 | Yes |
| 37 | PLEK2 | pleckstrin 2 [Source:HGNC Symbol;Acc:HGNC:19238] | 2481 | 0.719 | 0.8111 | Yes |
| 38 | PPP4R3B | protein phosphatase 4 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:29267] | 2562 | 0.691 | 0.8151 | Yes |
| 39 | ZSWIM8 | zinc finger SWIM-type containing 8 [Source:HGNC Symbol;Acc:HGNC:23528] | 3353 | 0.482 | 0.7981 | No |
| 40 | MCTP1 | multiple C2 and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26183] | 3458 | 0.462 | 0.7994 | No |
| 41 | RGS9 | regulator of G protein signaling 9 [Source:HGNC Symbol;Acc:HGNC:10004] | 4022 | 0.356 | 0.7873 | No |
| 42 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 4086 | 0.342 | 0.7887 | No |
| 43 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 4625 | 0.243 | 0.7763 | No |
| 44 | ATP6V1C1 | ATPase H+ transporting V1 subunit C1 [Source:HGNC Symbol;Acc:HGNC:856] | 4662 | 0.235 | 0.7774 | No |
| 45 | MT1H | metallothionein 1H [Source:HGNC Symbol;Acc:HGNC:7400] | 4864 | 0.204 | 0.7738 | No |
| 46 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 4969 | 0.187 | 0.7727 | No |
| 47 | SLC39A8 | solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862] | 5218 | 0.150 | 0.7673 | No |
| 48 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 5884 | 0.054 | 0.7499 | No |
| 49 | MCTP2 | multiple C2 and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25636] | 7780 | 0.000 | 0.6986 | No |
| 50 | POPDC3 | popeye domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17649] | 8516 | 0.000 | 0.6788 | No |
| 51 | SLC16A6P1 | SLC16A6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:48932] | 10285 | 0.000 | 0.6310 | No |
| 52 | B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:15684] | 10599 | 0.000 | 0.6226 | No |
| 53 | SLC6A15 | solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621] | 11664 | 0.000 | 0.5938 | No |
| 54 | PTGFR | prostaglandin F receptor [Source:HGNC Symbol;Acc:HGNC:9600] | 11680 | 0.000 | 0.5934 | No |
| 55 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13746 | 0.000 | 0.5376 | No |
| 56 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208] | 14299 | 0.000 | 0.5227 | No |
| 57 | EPB41L4B | erythrocyte membrane protein band 4.1 like 4B [Source:HGNC Symbol;Acc:HGNC:19818] | 14939 | 0.000 | 0.5054 | No |
| 58 | PRR7-AS1 | PRR7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27961] | 17047 | 0.000 | 0.4485 | No |
| 59 | SRSF12 | serine and arginine rich splicing factor 12 [Source:HGNC Symbol;Acc:HGNC:21220] | 17455 | 0.000 | 0.4375 | No |
| 60 | MMP1 | matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] | 18999 | 0.000 | 0.3958 | No |
| 61 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19334 | 0.000 | 0.3868 | No |
| 62 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19343 | 0.000 | 0.3866 | No |
| 63 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19345 | 0.000 | 0.3865 | No |
| 64 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19347 | 0.000 | 0.3865 | No |
| 65 | IFNE | interferon epsilon [Source:HGNC Symbol;Acc:HGNC:18163] | 20690 | 0.000 | 0.3502 | No |
| 66 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 21850 | 0.000 | 0.3189 | No |
| 67 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 21925 | 0.000 | 0.3169 | No |
| 68 | CD69 | CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694] | 22900 | 0.000 | 0.2906 | No |
| 69 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23458 | 0.000 | 0.2755 | No |
| 70 | C2CD4B | C2 calcium dependent domain containing 4B [Source:HGNC Symbol;Acc:HGNC:33628] | 24391 | 0.000 | 0.2504 | No |
| 71 | FGF2 | fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] | 25064 | 0.000 | 0.2322 | No |
| 72 | STC1 | stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373] | 27545 | -0.063 | 0.1658 | No |
| 73 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 28059 | -0.124 | 0.1530 | No |
| 74 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 28688 | -0.206 | 0.1379 | No |
| 75 | TESC | tescalcin [Source:HGNC Symbol;Acc:HGNC:26065] | 28721 | -0.212 | 0.1389 | No |
| 76 | IRAK3 | interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020] | 29853 | -0.360 | 0.1115 | No |
| 77 | MT1B | metallothionein 1B [Source:HGNC Symbol;Acc:HGNC:7394] | 29959 | -0.375 | 0.1120 | No |
| 78 | PHEX | phosphate regulating endopeptidase homolog X-linked [Source:HGNC Symbol;Acc:HGNC:8918] | 30410 | -0.437 | 0.1038 | No |
| 79 | SLC16A6 | solute carrier family 16 member 6 [Source:HGNC Symbol;Acc:HGNC:10927] | 32516 | -0.856 | 0.0545 | No |
| 80 | PLA2G4A | phospholipase A2 group IVA [Source:HGNC Symbol;Acc:HGNC:9035] | 32984 | -0.979 | 0.0507 | No |
| 81 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 33098 | -1.012 | 0.0566 | No |
| 82 | RNF128 | ring finger protein 128 [Source:HGNC Symbol;Acc:HGNC:21153] | 35543 | -2.076 | 0.0091 | No |
| 83 | LRRC8B | leucine rich repeat containing 8 VRAC subunit B [Source:HGNC Symbol;Acc:HGNC:30692] | 36857 | -3.658 | 0.0063 | No |
