Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ISHIDA_E2F_TARGETS |
| Enrichment Score (ES) | -0.8906113 |
| Normalized Enrichment Score (NES) | -1.7225556 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.964678E-5 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ANXA8L1 | annexin A8 like 1 [Source:HGNC Symbol;Acc:HGNC:23334] | 21932 | 0.000 | -0.5921 | No |
| 2 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 29558 | -0.319 | -0.7956 | No |
| 3 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32217 | -0.779 | -0.8615 | No |
| 4 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 32241 | -0.783 | -0.8563 | No |
| 5 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8741 | No |
| 6 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.8771 | No |
| 7 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 34129 | -1.359 | -0.8805 | Yes |
| 8 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34209 | -1.394 | -0.8722 | Yes |
| 9 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 34511 | -1.519 | -0.8690 | Yes |
| 10 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.8588 | Yes |
| 11 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 34906 | -1.690 | -0.8555 | Yes |
| 12 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34948 | -1.710 | -0.8439 | Yes |
| 13 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35107 | -1.803 | -0.8347 | Yes |
| 14 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35306 | -1.922 | -0.8257 | Yes |
| 15 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35462 | -2.024 | -0.8148 | Yes |
| 16 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35613 | -2.129 | -0.8030 | Yes |
| 17 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35634 | -2.139 | -0.7876 | Yes |
| 18 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35898 | -2.368 | -0.7770 | Yes |
| 19 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35996 | -2.449 | -0.7613 | Yes |
| 20 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 36013 | -2.468 | -0.7434 | Yes |
| 21 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 36189 | -2.647 | -0.7283 | Yes |
| 22 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36195 | -2.657 | -0.7087 | Yes |
| 23 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36231 | -2.691 | -0.6895 | Yes |
| 24 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.6694 | Yes |
| 25 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 36245 | -2.709 | -0.6496 | Yes |
| 26 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.6306 | Yes |
| 27 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36404 | -2.906 | -0.6111 | Yes |
| 28 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36408 | -2.907 | -0.5895 | Yes |
| 29 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36475 | -3.005 | -0.5688 | Yes |
| 30 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36596 | -3.195 | -0.5482 | Yes |
| 31 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.5244 | Yes |
| 32 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36602 | -3.206 | -0.5006 | Yes |
| 33 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 36609 | -3.217 | -0.4767 | Yes |
| 34 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.4529 | Yes |
| 35 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.4291 | Yes |
| 36 | ANLN | anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082] | 36657 | -3.298 | -0.4048 | Yes |
| 37 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36693 | -3.364 | -0.3806 | Yes |
| 38 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36704 | -3.383 | -0.3557 | Yes |
| 39 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36710 | -3.387 | -0.3305 | Yes |
| 40 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36790 | -3.518 | -0.3064 | Yes |
| 41 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36797 | -3.534 | -0.2802 | Yes |
| 42 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36809 | -3.551 | -0.2540 | Yes |
| 43 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.2277 | Yes |
| 44 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36856 | -3.657 | -0.2011 | Yes |
| 45 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36868 | -3.678 | -0.1740 | Yes |
| 46 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36871 | -3.689 | -0.1465 | Yes |
| 47 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.1189 | Yes |
| 48 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36915 | -3.854 | -0.0902 | Yes |
| 49 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36943 | -3.937 | -0.0616 | Yes |
| 50 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36992 | -4.105 | -0.0323 | Yes |
| 51 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37079 | -4.675 | 0.0003 | Yes |
