Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | KANG_DOXORUBICIN_RESISTANCE_UP |
| Enrichment Score (ES) | -0.8756275 |
| Normalized Enrichment Score (NES) | -1.6916819 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.4230983E-4 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797] | 764 | 1.796 | -0.0065 | No |
| 2 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 1110 | 1.419 | -0.0047 | No |
| 3 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 23814 | 0.000 | -0.6177 | No |
| 4 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25820 | 0.000 | -0.6718 | No |
| 5 | POLA2 | DNA polymerase alpha 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:30073] | 27587 | -0.068 | -0.7189 | No |
| 6 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 28025 | -0.122 | -0.7298 | No |
| 7 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 31175 | -0.560 | -0.8104 | No |
| 8 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32921 | -0.962 | -0.8500 | No |
| 9 | POLQ | DNA polymerase theta [Source:HGNC Symbol;Acc:HGNC:9186] | 33092 | -1.009 | -0.8466 | No |
| 10 | NEMP1 | nuclear envelope integral membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:29001] | 34167 | -1.377 | -0.8648 | Yes |
| 11 | NPIPA1 | nuclear pore complex interacting protein family member A1 [Source:HGNC Symbol;Acc:HGNC:7909] | 34339 | -1.449 | -0.8580 | Yes |
| 12 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.8519 | Yes |
| 13 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 34590 | -1.550 | -0.8405 | Yes |
| 14 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 34898 | -1.687 | -0.8355 | Yes |
| 15 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34948 | -1.710 | -0.8234 | Yes |
| 16 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35218 | -1.870 | -0.8160 | Yes |
| 17 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 35322 | -1.930 | -0.8036 | Yes |
| 18 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35430 | -1.996 | -0.7908 | Yes |
| 19 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35526 | -2.066 | -0.7771 | Yes |
| 20 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35565 | -2.097 | -0.7617 | Yes |
| 21 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35623 | -2.133 | -0.7465 | Yes |
| 22 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35629 | -2.136 | -0.7298 | Yes |
| 23 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35715 | -2.202 | -0.7148 | Yes |
| 24 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35883 | -2.351 | -0.7009 | Yes |
| 25 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35976 | -2.431 | -0.6842 | Yes |
| 26 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36006 | -2.459 | -0.6657 | Yes |
| 27 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36023 | -2.475 | -0.6467 | Yes |
| 28 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36050 | -2.499 | -0.6278 | Yes |
| 29 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 36054 | -2.502 | -0.6082 | Yes |
| 30 | BARD1 | BRCA1 associated RING domain 1 [Source:HGNC Symbol;Acc:HGNC:952] | 36117 | -2.567 | -0.5897 | Yes |
| 31 | NCAPG2 | non-SMC condensin II complex subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904] | 36141 | -2.588 | -0.5700 | Yes |
| 32 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 36181 | -2.640 | -0.5503 | Yes |
| 33 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.5305 | Yes |
| 34 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36318 | -2.818 | -0.5106 | Yes |
| 35 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.4886 | Yes |
| 36 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 36429 | -2.936 | -0.4683 | Yes |
| 37 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36438 | -2.948 | -0.4454 | Yes |
| 38 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36448 | -2.956 | -0.4224 | Yes |
| 39 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36465 | -2.988 | -0.3993 | Yes |
| 40 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36475 | -3.005 | -0.3759 | Yes |
| 41 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 36489 | -3.036 | -0.3524 | Yes |
| 42 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36512 | -3.058 | -0.3290 | Yes |
| 43 | DSCC1 | DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453] | 36555 | -3.131 | -0.3055 | Yes |
| 44 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.2818 | Yes |
| 45 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36620 | -3.234 | -0.2564 | Yes |
| 46 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36684 | -3.340 | -0.2319 | Yes |
| 47 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36710 | -3.387 | -0.2059 | Yes |
| 48 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36809 | -3.551 | -0.1807 | Yes |
| 49 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36856 | -3.657 | -0.1532 | Yes |
| 50 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36868 | -3.678 | -0.1246 | Yes |
| 51 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.0955 | Yes |
| 52 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36957 | -3.986 | -0.0654 | Yes |
| 53 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36988 | -4.101 | -0.0340 | Yes |
| 54 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37079 | -4.675 | 0.0003 | Yes |
