Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| Enrichment Score (ES) | -0.8429558 |
| Normalized Enrichment Score (NES) | -1.7211102 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.7235094E-5 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1039 | 1.503 | -0.0202 | No |
| 2 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 1635 | 1.068 | -0.0306 | No |
| 3 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 2048 | 0.881 | -0.0371 | No |
| 4 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2463 | 0.725 | -0.0445 | No |
| 5 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 3685 | 0.413 | -0.0753 | No |
| 6 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 4036 | 0.353 | -0.0829 | No |
| 7 | CBX1 | chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551] | 4438 | 0.273 | -0.0923 | No |
| 8 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 4956 | 0.190 | -0.1053 | No |
| 9 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12470 | 0.000 | -0.3083 | No |
| 10 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16665 | 0.000 | -0.4217 | No |
| 11 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18354 | 0.000 | -0.4673 | No |
| 12 | RAMP1 | receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843] | 20221 | 0.000 | -0.5177 | No |
| 13 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 23814 | 0.000 | -0.6148 | No |
| 14 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 27156 | -0.003 | -0.7051 | No |
| 15 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 27294 | -0.030 | -0.7086 | No |
| 16 | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101] | 28693 | -0.207 | -0.7453 | No |
| 17 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 29558 | -0.319 | -0.7670 | No |
| 18 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 30013 | -0.381 | -0.7773 | No |
| 19 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 30485 | -0.450 | -0.7876 | No |
| 20 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 30870 | -0.510 | -0.7953 | No |
| 21 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 31175 | -0.560 | -0.8006 | No |
| 22 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 31384 | -0.594 | -0.8031 | No |
| 23 | ACTN4 | actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166] | 32024 | -0.735 | -0.8165 | No |
| 24 | HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941] | 32826 | -0.932 | -0.8332 | No |
| 25 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8375 | Yes |
| 26 | UCK2 | uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562] | 33228 | -1.053 | -0.8330 | Yes |
| 27 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 33528 | -1.150 | -0.8350 | Yes |
| 28 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 33539 | -1.153 | -0.8292 | Yes |
| 29 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 33732 | -1.222 | -0.8280 | Yes |
| 30 | SLC16A1 | solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922] | 33909 | -1.283 | -0.8260 | Yes |
| 31 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 34033 | -1.321 | -0.8223 | Yes |
| 32 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 34184 | -1.384 | -0.8191 | Yes |
| 33 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 34289 | -1.430 | -0.8144 | Yes |
| 34 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 34418 | -1.480 | -0.8100 | Yes |
| 35 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 34511 | -1.519 | -0.8045 | Yes |
| 36 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.7977 | Yes |
| 37 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34573 | -1.544 | -0.7899 | Yes |
| 38 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 34590 | -1.550 | -0.7822 | Yes |
| 39 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34948 | -1.710 | -0.7828 | Yes |
| 40 | XRCC6 | X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055] | 35134 | -1.818 | -0.7782 | Yes |
| 41 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35462 | -2.024 | -0.7764 | Yes |
| 42 | CKAP5 | cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] | 35489 | -2.041 | -0.7664 | Yes |
| 43 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35601 | -2.118 | -0.7582 | Yes |
| 44 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35613 | -2.129 | -0.7473 | Yes |
| 45 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35634 | -2.139 | -0.7366 | Yes |
| 46 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 35752 | -2.227 | -0.7280 | Yes |
| 47 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 35896 | -2.366 | -0.7194 | Yes |
| 48 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35996 | -2.449 | -0.7092 | Yes |
| 49 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 36013 | -2.468 | -0.6966 | Yes |
| 50 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36021 | -2.474 | -0.6838 | Yes |
| 51 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 36054 | -2.502 | -0.6715 | Yes |
| 52 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 36076 | -2.525 | -0.6587 | Yes |
| 53 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36121 | -2.570 | -0.6464 | Yes |
| 54 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36195 | -2.657 | -0.6343 | Yes |
| 55 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36231 | -2.691 | -0.6211 | Yes |
| 56 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.6069 | Yes |
| 57 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 36270 | -2.741 | -0.5935 | Yes |
| 58 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36278 | -2.752 | -0.5792 | Yes |
| 59 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.5655 | Yes |
| 60 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36333 | -2.835 | -0.5508 | Yes |
| 61 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36404 | -2.906 | -0.5374 | Yes |
| 62 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.5231 | Yes |
| 63 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 36527 | -3.075 | -0.5088 | Yes |
| 64 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36533 | -3.091 | -0.4926 | Yes |
| 65 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36549 | -3.110 | -0.4767 | Yes |
| 66 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 36569 | -3.154 | -0.4606 | Yes |
| 67 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.4444 | Yes |
| 68 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.4280 | Yes |
| 69 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36622 | -3.236 | -0.4110 | Yes |
| 70 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.3944 | Yes |
| 71 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36652 | -3.287 | -0.3772 | Yes |
| 72 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36690 | -3.355 | -0.3605 | Yes |
| 73 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36693 | -3.364 | -0.3428 | Yes |
| 74 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 36703 | -3.380 | -0.3253 | Yes |
| 75 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36704 | -3.383 | -0.3074 | Yes |
| 76 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36710 | -3.387 | -0.2897 | Yes |
| 77 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36717 | -3.397 | -0.2720 | Yes |
| 78 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36778 | -3.498 | -0.2552 | Yes |
| 79 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36790 | -3.518 | -0.2370 | Yes |
| 80 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36798 | -3.535 | -0.2185 | Yes |
| 81 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.2004 | Yes |
| 82 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36856 | -3.657 | -0.1818 | Yes |
| 83 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36868 | -3.678 | -0.1627 | Yes |
| 84 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.1436 | Yes |
| 85 | PTGR1 | prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429] | 36912 | -3.844 | -0.1234 | Yes |
| 86 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36915 | -3.854 | -0.1031 | Yes |
| 87 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36925 | -3.878 | -0.0829 | Yes |
| 88 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36992 | -4.105 | -0.0631 | Yes |
| 89 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36993 | -4.108 | -0.0415 | Yes |
| 90 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37012 | -4.172 | -0.0200 | Yes |
| 91 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 37016 | -4.184 | 0.0020 | Yes |
