Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.92517966 |
| Normalized Enrichment Score (NES) | 2.3434596 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 6 | 4.961 | 0.0251 | Yes |
| 2 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 10 | 4.929 | 0.0501 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 41 | 4.677 | 0.0732 | Yes |
| 4 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 42 | 4.653 | 0.0969 | Yes |
| 5 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 50 | 4.531 | 0.1198 | Yes |
| 6 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 70 | 4.306 | 0.1412 | Yes |
| 7 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 80 | 4.213 | 0.1624 | Yes |
| 8 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 81 | 4.209 | 0.1838 | Yes |
| 9 | BCL2L1 | BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992] | 88 | 4.152 | 0.2048 | Yes |
| 10 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 91 | 4.136 | 0.2258 | Yes |
| 11 | PNP | purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892] | 95 | 4.075 | 0.2465 | Yes |
| 12 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 96 | 4.072 | 0.2673 | Yes |
| 13 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 124 | 3.892 | 0.2864 | Yes |
| 14 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 134 | 3.807 | 0.3055 | Yes |
| 15 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 136 | 3.791 | 0.3248 | Yes |
| 16 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 152 | 3.690 | 0.3432 | Yes |
| 17 | CFLAR | CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876] | 172 | 3.591 | 0.3610 | Yes |
| 18 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 173 | 3.588 | 0.3792 | Yes |
| 19 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 201 | 3.397 | 0.3958 | Yes |
| 20 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 207 | 3.333 | 0.4127 | Yes |
| 21 | GK | glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289] | 214 | 3.275 | 0.4292 | Yes |
| 22 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 216 | 3.268 | 0.4458 | Yes |
| 23 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 226 | 3.208 | 0.4619 | Yes |
| 24 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 227 | 3.202 | 0.4782 | Yes |
| 25 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 228 | 3.201 | 0.4945 | Yes |
| 26 | RHOC | ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669] | 231 | 3.193 | 0.5107 | Yes |
| 27 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 232 | 3.191 | 0.5270 | Yes |
| 28 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 234 | 3.182 | 0.5432 | Yes |
| 29 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 235 | 3.171 | 0.5593 | Yes |
| 30 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 237 | 3.163 | 0.5754 | Yes |
| 31 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 284 | 2.946 | 0.5892 | Yes |
| 32 | IRGM | immunity related GTPase M [Source:HGNC Symbol;Acc:HGNC:29597] | 302 | 2.872 | 0.6034 | Yes |
| 33 | SRGN | serglycin [Source:HGNC Symbol;Acc:HGNC:9361] | 315 | 2.849 | 0.6175 | Yes |
| 34 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 327 | 2.809 | 0.6316 | Yes |
| 35 | STK10 | serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388] | 335 | 2.777 | 0.6455 | Yes |
| 36 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 343 | 2.737 | 0.6593 | Yes |
| 37 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 357 | 2.683 | 0.6726 | Yes |
| 38 | IFRD1 | interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456] | 373 | 2.620 | 0.6855 | Yes |
| 39 | HCLS1 | hematopoietic cell-specific Lyn substrate 1 [Source:HGNC Symbol;Acc:HGNC:4844] | 374 | 2.619 | 0.6989 | Yes |
| 40 | LCP2 | lymphocyte cytosolic protein 2 [Source:HGNC Symbol;Acc:HGNC:6529] | 389 | 2.584 | 0.7117 | Yes |
| 41 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 406 | 2.528 | 0.7241 | Yes |
| 42 | IL1RL1 | interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] | 461 | 2.388 | 0.7348 | Yes |
| 43 | TGFB1 | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | 474 | 2.360 | 0.7465 | Yes |
| 44 | MYO10 | myosin X [Source:HGNC Symbol;Acc:HGNC:7593] | 488 | 2.324 | 0.7580 | Yes |
| 45 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 506 | 2.270 | 0.7691 | Yes |
| 46 | ATF3 | activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785] | 526 | 2.244 | 0.7800 | Yes |
| 47 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 547 | 2.184 | 0.7906 | Yes |
| 48 | CLN3 | CLN3 lysosomal/endosomal transmembrane protein, battenin [Source:HGNC Symbol;Acc:HGNC:2074] | 578 | 2.128 | 0.8006 | Yes |
| 49 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 670 | 1.967 | 0.8082 | Yes |
| 50 | RNF11 | ring finger protein 11 [Source:HGNC Symbol;Acc:HGNC:10056] | 695 | 1.919 | 0.8173 | Yes |
| 51 | ETF1 | eukaryotic translation termination factor 1 [Source:HGNC Symbol;Acc:HGNC:3477] | 702 | 1.902 | 0.8268 | Yes |
| 52 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 765 | 1.794 | 0.8343 | Yes |
| 53 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 775 | 1.781 | 0.8431 | Yes |
| 54 | SLC20A1 | solute carrier family 20 member 1 [Source:HGNC Symbol;Acc:HGNC:10946] | 864 | 1.678 | 0.8493 | Yes |
| 55 | DEGS1 | delta 4-desaturase, sphingolipid 1 [Source:HGNC Symbol;Acc:HGNC:13709] | 890 | 1.654 | 0.8571 | Yes |
| 56 | CLEC4D | C-type lectin domain family 4 member D [Source:HGNC Symbol;Acc:HGNC:14554] | 898 | 1.645 | 0.8652 | Yes |
| 57 | JUND | JunD proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6206] | 912 | 1.636 | 0.8732 | Yes |
| 58 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 945 | 1.611 | 0.8806 | Yes |
| 59 | APBB1IP | amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379] | 949 | 1.607 | 0.8887 | Yes |
| 60 | EIF1 | eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249] | 1066 | 1.465 | 0.8930 | Yes |
| 61 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] | 1071 | 1.461 | 0.9003 | Yes |
| 62 | MAP2K1 | mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840] | 1172 | 1.371 | 0.9046 | Yes |
| 63 | MLLT11 | MLLT11 transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997] | 1380 | 1.216 | 0.9052 | Yes |
| 64 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1419 | 1.192 | 0.9103 | Yes |
| 65 | SLC2A1 | solute carrier family 2 member 1 [Source:HGNC Symbol;Acc:HGNC:11005] | 1494 | 1.148 | 0.9141 | Yes |
| 66 | WSB1 | WD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:19221] | 1692 | 1.038 | 0.9141 | Yes |
| 67 | KPNA3 | karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396] | 1730 | 1.014 | 0.9182 | Yes |
| 68 | RCN1 | reticulocalbin 1 [Source:HGNC Symbol;Acc:HGNC:9934] | 1932 | 0.930 | 0.9175 | Yes |
| 69 | TOP1 | DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986] | 1938 | 0.926 | 0.9221 | Yes |
| 70 | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 [Source:HGNC Symbol;Acc:HGNC:1987] | 2061 | 0.876 | 0.9233 | Yes |
| 71 | PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase type 1 beta [Source:HGNC Symbol;Acc:HGNC:8995] | 2150 | 0.838 | 0.9252 | Yes |
| 72 | SAP30 | Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532] | 2892 | 0.592 | 0.9082 | No |
| 73 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 3005 | 0.564 | 0.9080 | No |
| 74 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 3735 | 0.404 | 0.8904 | No |
| 75 | PRKCD | protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399] | 3782 | 0.397 | 0.8912 | No |
| 76 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 4036 | 0.353 | 0.8861 | No |
| 77 | FCGR2B | Fc fragment of IgG receptor IIb [Source:HGNC Symbol;Acc:HGNC:3618] | 5044 | 0.176 | 0.8598 | No |
| 78 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6263 | 0.000 | 0.8269 | No |
| 79 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8653 | 0.000 | 0.7623 | No |
| 80 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 9095 | 0.000 | 0.7504 | No |
| 81 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11315 | 0.000 | 0.6905 | No |
| 82 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13366 | 0.000 | 0.6351 | No |
| 83 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 26444 | 0.000 | 0.2817 | No |
| 84 | MAPKAPK2 | MAPK activated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:6887] | 29444 | -0.306 | 0.2022 | No |
| 85 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 32552 | -0.862 | 0.1226 | No |
