Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | REACTOME_FCGR_ACTIVATION |
| Enrichment Score (ES) | 0.9248015 |
| Normalized Enrichment Score (NES) | 2.2668424 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 226 | 3.208 | 0.1750 | Yes |
| 2 | FGR | FGR proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3697] | 240 | 3.146 | 0.3523 | Yes |
| 3 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 333 | 2.781 | 0.5067 | Yes |
| 4 | LYN | LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735] | 348 | 2.711 | 0.6594 | Yes |
| 5 | FCGR2A | Fc fragment of IgG receptor IIa [Source:HGNC Symbol;Acc:HGNC:3616] | 874 | 1.669 | 0.7394 | Yes |
| 6 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 1632 | 1.070 | 0.7794 | Yes |
| 7 | FYN | FYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4037] | 1891 | 0.949 | 0.8260 | Yes |
| 8 | YES1 | YES proto-oncogene 1, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12841] | 2000 | 0.901 | 0.8739 | Yes |
| 9 | CD247 | CD247 molecule [Source:HGNC Symbol;Acc:HGNC:1677] | 2662 | 0.661 | 0.8934 | Yes |
| 10 | FCGR1A | Fc fragment of IgG receptor Ia [Source:HGNC Symbol;Acc:HGNC:3613] | 2793 | 0.619 | 0.9248 | Yes |
| 11 | IGHV2-70 | immunoglobulin heavy variable 2-70 [Source:HGNC Symbol;Acc:HGNC:5577] | 6345 | 0.000 | 0.8289 | No |
| 12 | IGHV1-69 | immunoglobulin heavy variable 1-69 [Source:HGNC Symbol;Acc:HGNC:5558] | 7111 | 0.000 | 0.8082 | No |
| 13 | IGHV1-46 | immunoglobulin heavy variable 1-46 [Source:HGNC Symbol;Acc:HGNC:5554] | 7141 | 0.000 | 0.8074 | No |
| 14 | IGLV7-43 | immunoglobulin lambda variable 7-43 [Source:HGNC Symbol;Acc:HGNC:5929] | 7763 | 0.000 | 0.7907 | No |
| 15 | IGKV2-28 | immunoglobulin kappa variable 2-28 [Source:HGNC Symbol;Acc:HGNC:5783] | 7772 | 0.000 | 0.7904 | No |
| 16 | IGKV2-30 | immunoglobulin kappa variable 2-30 [Source:HGNC Symbol;Acc:HGNC:5785] | 7781 | 0.000 | 0.7902 | No |
| 17 | IGHV3-7 | immunoglobulin heavy variable 3-7 [Source:HGNC Symbol;Acc:HGNC:5620] | 8954 | 0.000 | 0.7586 | No |
| 18 | IGHV4-59 | immunoglobulin heavy variable 4-59 [Source:HGNC Symbol;Acc:HGNC:5654] | 11001 | 0.000 | 0.7033 | No |
| 19 | IGHV4-34 | immunoglobulin heavy variable 4-34 [Source:HGNC Symbol;Acc:HGNC:5650] | 11015 | 0.000 | 0.7030 | No |
| 20 | IGHV4-39 | immunoglobulin heavy variable 4-39 [Source:HGNC Symbol;Acc:HGNC:5651] | 11016 | 0.000 | 0.7030 | No |
| 21 | FCGR3A | Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619] | 11290 | 0.000 | 0.6956 | No |
| 22 | IGLV3-19 | immunoglobulin lambda variable 3-19 [Source:HGNC Symbol;Acc:HGNC:5903] | 11563 | 0.000 | 0.6882 | No |
| 23 | IGLV3-25 | immunoglobulin lambda variable 3-25 [Source:HGNC Symbol;Acc:HGNC:5908] | 11567 | 0.000 | 0.6882 | No |
| 24 | IGLV3-27 | immunoglobulin lambda variable 3-27 [Source:HGNC Symbol;Acc:HGNC:5910] | 11569 | 0.000 | 0.6881 | No |
| 25 | IGLV3-21 | immunoglobulin lambda variable 3-21 [Source:HGNC Symbol;Acc:HGNC:5905] | 11570 | 0.000 | 0.6881 | No |
| 26 | IGLV3-1 | immunoglobulin lambda variable 3-1 [Source:HGNC Symbol;Acc:HGNC:5896] | 12505 | 0.000 | 0.6629 | No |
| 27 | IGKV1-39 | immunoglobulin kappa variable 1-39 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5740] | 12511 | 0.000 | 0.6628 | No |
| 28 | IGKV1-33 | immunoglobulin kappa variable 1-33 [Source:HGNC Symbol;Acc:HGNC:5737] | 12521 | 0.000 | 0.6625 | No |
| 29 | IGKV1-16 | immunoglobulin kappa variable 1-16 [Source:HGNC Symbol;Acc:HGNC:5732] | 12540 | 0.000 | 0.6620 | No |
| 30 | IGKV1-17 | immunoglobulin kappa variable 1-17 [Source:HGNC Symbol;Acc:HGNC:5733] | 12541 | 0.000 | 0.6620 | No |
| 31 | IGKV1-12 | immunoglobulin kappa variable 1-12 [Source:HGNC Symbol;Acc:HGNC:5730] | 12542 | 0.000 | 0.6620 | No |
| 32 | IGKV2D-28 | immunoglobulin kappa variable 2D-28 [Source:HGNC Symbol;Acc:HGNC:5799] | 12665 | 0.000 | 0.6587 | No |
| 33 | IGKV2D-30 | immunoglobulin kappa variable 2D-30 [Source:HGNC Symbol;Acc:HGNC:5801] | 12674 | 0.000 | 0.6585 | No |
| 34 | IGKV2D-40 | immunoglobulin kappa variable 2D-40 [Source:HGNC Symbol;Acc:HGNC:5804] | 12678 | 0.000 | 0.6584 | No |
| 35 | IGKV5-2 | immunoglobulin kappa variable 5-2 [Source:HGNC Symbol;Acc:HGNC:5835] | 13856 | 0.000 | 0.6267 | No |
| 36 | IGLV2-8 | immunoglobulin lambda variable 2-8 [Source:HGNC Symbol;Acc:HGNC:5895] | 14871 | 0.000 | 0.5993 | No |
| 37 | IGLV2-11 | immunoglobulin lambda variable 2-11 [Source:HGNC Symbol;Acc:HGNC:5887] | 16156 | 0.000 | 0.5646 | No |
| 38 | IGLV2-14 | immunoglobulin lambda variable 2-14 [Source:HGNC Symbol;Acc:HGNC:5888] | 16157 | 0.000 | 0.5646 | No |
| 39 | IGLV2-23 | immunoglobulin lambda variable 2-23 [Source:HGNC Symbol;Acc:HGNC:5890] | 16164 | 0.000 | 0.5644 | No |
| 40 | IGHG4 | immunoglobulin heavy constant gamma 4 (G4m marker) [Source:HGNC Symbol;Acc:HGNC:5528] | 17103 | 0.000 | 0.5391 | No |
| 41 | IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) [Source:HGNC Symbol;Acc:HGNC:5525] | 17106 | 0.000 | 0.5390 | No |
| 42 | IGHG2 | immunoglobulin heavy constant gamma 2 (G2m marker) [Source:HGNC Symbol;Acc:HGNC:5526] | 17108 | 0.000 | 0.5390 | No |
| 43 | IGLC3 | immunoglobulin lambda constant 3 (Kern-Oz+ marker) [Source:HGNC Symbol;Acc:HGNC:5857] | 17662 | 0.000 | 0.5241 | No |
| 44 | IGLC2 | immunoglobulin lambda constant 2 [Source:HGNC Symbol;Acc:HGNC:5856] | 17666 | 0.000 | 0.5240 | No |
| 45 | IGHV3-23 | immunoglobulin heavy variable 3-23 [Source:HGNC Symbol;Acc:HGNC:5588] | 17917 | 0.000 | 0.5172 | No |
| 46 | IGHV3-30 | immunoglobulin heavy variable 3-30 [Source:HGNC Symbol;Acc:HGNC:5591] | 17935 | 0.000 | 0.5168 | No |
| 47 | IGHV3-33 | immunoglobulin heavy variable 3-33 [Source:HGNC Symbol;Acc:HGNC:5596] | 17938 | 0.000 | 0.5167 | No |
| 48 | IGHV3-11 | immunoglobulin heavy variable 3-11 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5580] | 17977 | 0.000 | 0.5157 | No |
| 49 | IGHV3-13 | immunoglobulin heavy variable 3-13 [Source:HGNC Symbol;Acc:HGNC:5581] | 17980 | 0.000 | 0.5156 | No |
| 50 | IGHV3-48 | immunoglobulin heavy variable 3-48 [Source:HGNC Symbol;Acc:HGNC:5606] | 18154 | 0.000 | 0.5110 | No |
| 51 | IGHV3-53 | immunoglobulin heavy variable 3-53 [Source:HGNC Symbol;Acc:HGNC:5610] | 18163 | 0.000 | 0.5108 | No |
| 52 | IGKV1-5 | immunoglobulin kappa variable 1-5 [Source:HGNC Symbol;Acc:HGNC:5741] | 18212 | 0.000 | 0.5095 | No |
| 53 | IGKV4-1 | immunoglobulin kappa variable 4-1 [Source:HGNC Symbol;Acc:HGNC:5834] | 19193 | 0.000 | 0.4830 | No |
| 54 | IGKV1D-39 | immunoglobulin kappa variable 1D-39 [Source:HGNC Symbol;Acc:HGNC:5756] | 22646 | 0.000 | 0.3897 | No |
| 55 | IGKV1D-33 | immunoglobulin kappa variable 1D-33 [Source:HGNC Symbol;Acc:HGNC:5753] | 22648 | 0.000 | 0.3897 | No |
| 56 | IGKV1D-16 | immunoglobulin kappa variable 1D-16 [Source:HGNC Symbol;Acc:HGNC:5748] | 22680 | 0.000 | 0.3889 | No |
| 57 | IGKV1D-12 | immunoglobulin kappa variable 1D-12 [Source:HGNC Symbol;Acc:HGNC:5746] | 22687 | 0.000 | 0.3887 | No |
| 58 | CD3G | CD3g molecule [Source:HGNC Symbol;Acc:HGNC:1675] | 22812 | 0.000 | 0.3854 | No |
| 59 | IGLV6-57 | immunoglobulin lambda variable 6-57 [Source:HGNC Symbol;Acc:HGNC:5927] | 22919 | 0.000 | 0.3825 | No |
| 60 | IGKV3D-20 | immunoglobulin kappa variable 3D-20 [Source:HGNC Symbol;Acc:HGNC:5825] | 23574 | 0.000 | 0.3648 | No |
| 61 | IGLV1-40 | immunoglobulin lambda variable 1-40 [Source:HGNC Symbol;Acc:HGNC:5877] | 24291 | 0.000 | 0.3455 | No |
| 62 | IGLV1-47 | immunoglobulin lambda variable 1-47 [Source:HGNC Symbol;Acc:HGNC:5880] | 24292 | 0.000 | 0.3455 | No |
| 63 | IGLV1-44 | immunoglobulin lambda variable 1-44 [Source:HGNC Symbol;Acc:HGNC:5879] | 24293 | 0.000 | 0.3455 | No |
| 64 | IGLV1-51 | immunoglobulin lambda variable 1-51 [Source:HGNC Symbol;Acc:HGNC:5882] | 24307 | 0.000 | 0.3451 | No |
| 65 | IGKV3-15 | immunoglobulin kappa variable 3-15 [Source:HGNC Symbol;Acc:HGNC:5816] | 24832 | 0.000 | 0.3310 | No |
| 66 | IGKV3-11 | immunoglobulin kappa variable 3-11 [Source:HGNC Symbol;Acc:HGNC:5815] | 24839 | 0.000 | 0.3308 | No |
| 67 | IGKV3-20 | immunoglobulin kappa variable 3-20 [Source:HGNC Symbol;Acc:HGNC:5817] | 24865 | 0.000 | 0.3302 | No |
| 68 | IGHV1-2 | immunoglobulin heavy variable 1-2 [Source:HGNC Symbol;Acc:HGNC:5550] | 26542 | 0.000 | 0.2849 | No |
| 69 | IGHV2-5 | immunoglobulin heavy variable 2-5 [Source:HGNC Symbol;Acc:HGNC:5576] | 26952 | 0.000 | 0.2738 | No |
