Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | SEKI_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.8487194 |
| Normalized Enrichment Score (NES) | 2.0995147 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 2 | 4.994 | 0.0337 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 14 | 4.897 | 0.0665 | Yes |
| 3 | GBP6 | guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395] | 19 | 4.854 | 0.0992 | Yes |
| 4 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 26 | 4.779 | 0.1313 | Yes |
| 5 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 34 | 4.731 | 0.1631 | Yes |
| 6 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 44 | 4.595 | 0.1939 | Yes |
| 7 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 71 | 4.291 | 0.2221 | Yes |
| 8 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 73 | 4.254 | 0.2509 | Yes |
| 9 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 86 | 4.166 | 0.2787 | Yes |
| 10 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 96 | 4.072 | 0.3060 | Yes |
| 11 | ZC3H12A | zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259] | 116 | 3.937 | 0.3320 | Yes |
| 12 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 122 | 3.897 | 0.3582 | Yes |
| 13 | RND1 | Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314] | 125 | 3.891 | 0.3845 | Yes |
| 14 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 152 | 3.690 | 0.4087 | Yes |
| 15 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 156 | 3.677 | 0.4335 | Yes |
| 16 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 158 | 3.659 | 0.4582 | Yes |
| 17 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 166 | 3.616 | 0.4824 | Yes |
| 18 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 173 | 3.588 | 0.5065 | Yes |
| 19 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 204 | 3.345 | 0.5283 | Yes |
| 20 | SLC4A7 | solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033] | 208 | 3.330 | 0.5507 | Yes |
| 21 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 216 | 3.268 | 0.5726 | Yes |
| 22 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 234 | 3.182 | 0.5936 | Yes |
| 23 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 256 | 3.068 | 0.6138 | Yes |
| 24 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 275 | 2.999 | 0.6336 | Yes |
| 25 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 316 | 2.847 | 0.6517 | Yes |
| 26 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 338 | 2.762 | 0.6698 | Yes |
| 27 | ZMYND15 | zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] | 359 | 2.675 | 0.6873 | Yes |
| 28 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 396 | 2.549 | 0.7036 | Yes |
| 29 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 410 | 2.520 | 0.7203 | Yes |
| 30 | SLC11A2 | solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908] | 438 | 2.433 | 0.7360 | Yes |
| 31 | SH3PXD2B | SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242] | 445 | 2.422 | 0.7522 | Yes |
| 32 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 453 | 2.407 | 0.7683 | Yes |
| 33 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 503 | 2.286 | 0.7824 | Yes |
| 34 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 634 | 2.013 | 0.7925 | Yes |
| 35 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 654 | 1.986 | 0.8054 | Yes |
| 36 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 698 | 1.916 | 0.8171 | Yes |
| 37 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 749 | 1.814 | 0.8281 | Yes |
| 38 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 755 | 1.813 | 0.8402 | Yes |
| 39 | FAS | Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920] | 1064 | 1.467 | 0.8418 | Yes |
| 40 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1327 | 1.250 | 0.8431 | Yes |
| 41 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1419 | 1.192 | 0.8487 | Yes |
| 42 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 2685 | 0.657 | 0.8190 | No |
| 43 | EXOC3L4 | exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120] | 2758 | 0.630 | 0.8213 | No |
| 44 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4325 | 0.292 | 0.7810 | No |
| 45 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 4625 | 0.243 | 0.7745 | No |
| 46 | SELE | selectin E [Source:HGNC Symbol;Acc:HGNC:10718] | 7007 | 0.000 | 0.7102 | No |
| 47 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8418 | 0.000 | 0.6721 | No |
| 48 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8551 | 0.000 | 0.6685 | No |
| 49 | NGFR | nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809] | 10193 | 0.000 | 0.6242 | No |
| 50 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11042 | 0.000 | 0.6013 | No |
| 51 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11340 | 0.000 | 0.5933 | No |
| 52 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13797 | 0.000 | 0.5269 | No |
| 53 | LRATD1 | LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743] | 17952 | 0.000 | 0.4147 | No |
| 54 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18173 | 0.000 | 0.4087 | No |
| 55 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18785 | 0.000 | 0.3922 | No |
| 56 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18898 | 0.000 | 0.3892 | No |
| 57 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19329 | 0.000 | 0.3776 | No |
| 58 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19343 | 0.000 | 0.3772 | No |
| 59 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19345 | 0.000 | 0.3772 | No |
| 60 | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223] | 19925 | 0.000 | 0.3616 | No |
| 61 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 21925 | 0.000 | 0.3075 | No |
| 62 | EGFR | epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236] | 21957 | 0.000 | 0.3067 | No |
| 63 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22725 | 0.000 | 0.2860 | No |
| 64 | SCHIP1 | schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678] | 23270 | 0.000 | 0.2713 | No |
| 65 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 26444 | 0.000 | 0.1856 | No |
| 66 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 27756 | -0.088 | 0.1507 | No |
| 67 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 28059 | -0.124 | 0.1434 | No |
| 68 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 28521 | -0.185 | 0.1322 | No |
| 69 | NEURL3 | neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] | 31051 | -0.539 | 0.0675 | No |
| 70 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 31802 | -0.679 | 0.0519 | No |
| 71 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 33020 | -0.989 | 0.0257 | No |
| 72 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 33098 | -1.012 | 0.0304 | No |
| 73 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 34605 | -1.557 | 0.0002 | No |
| 74 | RFX5 | regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986] | 34991 | -1.733 | 0.0015 | No |
| 75 | SLCO4A1 | solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] | 35120 | -1.808 | 0.0103 | No |
| 76 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 35262 | -1.901 | 0.0193 | No |
| 77 | BMP2 | bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069] | 35641 | -2.145 | 0.0236 | No |
| 78 | TJP2 | tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828] | 35833 | -2.295 | 0.0340 | No |
