Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | WORSCHECH_TUMOR_REJECTION_UP |
| Enrichment Score (ES) | 0.8464563 |
| Normalized Enrichment Score (NES) | 2.032197 |
| Nominal p-value | 0.0 |
| FDR q-value | 9.778812E-5 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.995 | 0.0775 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.991 | 0.1550 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 9 | 4.938 | 0.2315 | Yes |
| 4 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 26 | 4.779 | 0.3053 | Yes |
| 5 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 28 | 4.772 | 0.3793 | Yes |
| 6 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 41 | 4.677 | 0.4516 | Yes |
| 7 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 63 | 4.395 | 0.5193 | Yes |
| 8 | IL4I1 | interleukin 4 induced 1 [Source:HGNC Symbol;Acc:HGNC:19094] | 77 | 4.239 | 0.5847 | Yes |
| 9 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 99 | 4.056 | 0.6471 | Yes |
| 10 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 227 | 3.202 | 0.6934 | Yes |
| 11 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 551 | 2.174 | 0.7184 | Yes |
| 12 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 560 | 2.161 | 0.7518 | Yes |
| 13 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 570 | 2.140 | 0.7847 | Yes |
| 14 | TLR6 | toll like receptor 6 [Source:HGNC Symbol;Acc:HGNC:16711] | 576 | 2.130 | 0.8177 | Yes |
| 15 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 836 | 1.712 | 0.8373 | Yes |
| 16 | NKRF | NFKB repressing factor [Source:HGNC Symbol;Acc:HGNC:19374] | 1383 | 1.213 | 0.8413 | Yes |
| 17 | IRF4 | interferon regulatory factor 4 [Source:HGNC Symbol;Acc:HGNC:6119] | 2082 | 0.867 | 0.8360 | Yes |
| 18 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2170 | 0.828 | 0.8465 | Yes |
| 19 | CKLF | chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253] | 2797 | 0.619 | 0.8392 | No |
| 20 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 3190 | 0.519 | 0.8366 | No |
| 21 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 4925 | 0.194 | 0.7928 | No |
| 22 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 4979 | 0.186 | 0.7943 | No |
| 23 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 5084 | 0.170 | 0.7941 | No |
| 24 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 5426 | 0.118 | 0.7867 | No |
| 25 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 5950 | 0.041 | 0.7732 | No |
| 26 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6234 | 0.000 | 0.7656 | No |
| 27 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6263 | 0.000 | 0.7649 | No |
| 28 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6264 | 0.000 | 0.7649 | No |
| 29 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8551 | 0.000 | 0.7031 | No |
| 30 | LY6H | lymphocyte antigen 6 family member H [Source:HGNC Symbol;Acc:HGNC:6728] | 9012 | 0.000 | 0.6907 | No |
| 31 | TNFRSF4 | TNF receptor superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11918] | 9627 | 0.000 | 0.6741 | No |
| 32 | ACKR1 | atypical chemokine receptor 1 (Duffy blood group) [Source:HGNC Symbol;Acc:HGNC:4035] | 10937 | 0.000 | 0.6388 | No |
| 33 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11315 | 0.000 | 0.6286 | No |
| 34 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12001 | 0.000 | 0.6101 | No |
| 35 | TNFSF11 | TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926] | 12387 | 0.000 | 0.5997 | No |
| 36 | TCL1B | T cell leukemia/lymphoma 1B [Source:HGNC Symbol;Acc:HGNC:11649] | 13005 | 0.000 | 0.5830 | No |
| 37 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13366 | 0.000 | 0.5733 | No |
| 38 | IL31 | interleukin 31 [Source:HGNC Symbol;Acc:HGNC:19372] | 13749 | 0.000 | 0.5630 | No |
| 39 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14230 | 0.000 | 0.5500 | No |
| 40 | EBF4 | EBF family member 4 [Source:HGNC Symbol;Acc:HGNC:29278] | 14892 | 0.000 | 0.5322 | No |
| 41 | IL17RB | interleukin 17 receptor B [Source:HGNC Symbol;Acc:HGNC:18015] | 14958 | 0.000 | 0.5304 | No |
| 42 | IL36G | interleukin 36 gamma [Source:HGNC Symbol;Acc:HGNC:15741] | 15633 | 0.000 | 0.5122 | No |
| 43 | CLEC10A | C-type lectin domain containing 10A [Source:HGNC Symbol;Acc:HGNC:16916] | 15720 | 0.000 | 0.5099 | No |
| 44 | IL23R | interleukin 23 receptor [Source:HGNC Symbol;Acc:HGNC:19100] | 15845 | 0.000 | 0.5065 | No |
| 45 | IL5 | interleukin 5 [Source:HGNC Symbol;Acc:HGNC:6016] | 17653 | 0.000 | 0.4577 | No |
| 46 | ITK | IL2 inducible T cell kinase [Source:HGNC Symbol;Acc:HGNC:6171] | 17713 | 0.000 | 0.4561 | No |
| 47 | IFNA13 | interferon alpha 13 [Source:HGNC Symbol;Acc:HGNC:5419] | 18098 | 0.000 | 0.4458 | No |
| 48 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19345 | 0.000 | 0.4121 | No |
| 49 | FASLG | Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936] | 20147 | 0.000 | 0.3905 | No |
| 50 | IFNG | interferon gamma [Source:HGNC Symbol;Acc:HGNC:5438] | 20687 | 0.000 | 0.3759 | No |
| 51 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22723 | 0.000 | 0.3210 | No |
| 52 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 22733 | 0.000 | 0.3207 | No |
| 53 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 23677 | 0.000 | 0.2953 | No |
| 54 | IL17F | interleukin 17F [Source:HGNC Symbol;Acc:HGNC:16404] | 26682 | 0.000 | 0.2141 | No |
| 55 | JCHAIN | joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713] | 27073 | 0.000 | 0.2036 | No |
| 56 | IRF6 | interferon regulatory factor 6 [Source:HGNC Symbol;Acc:HGNC:6121] | 27417 | -0.048 | 0.1951 | No |
| 57 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 29282 | -0.285 | 0.1492 | No |
| 58 | TAGAP | T cell activation RhoGTPase activating protein [Source:HGNC Symbol;Acc:HGNC:15669] | 30058 | -0.388 | 0.1343 | No |
| 59 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 30715 | -0.484 | 0.1241 | No |
| 60 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 31688 | -0.653 | 0.1080 | No |
| 61 | NKIRAS2 | NFKB inhibitor interacting Ras like 2 [Source:HGNC Symbol;Acc:HGNC:17898] | 33683 | -1.204 | 0.0728 | No |
| 62 | TLR4 | toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850] | 33764 | -1.235 | 0.0898 | No |
