Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_CCNB2 |
| Enrichment Score (ES) | -0.8972655 |
| Normalized Enrichment Score (NES) | -1.7435813 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2357 | 0.761 | -0.0587 | No |
| 2 | UBE2S | ubiquitin conjugating enzyme E2 S [Source:HGNC Symbol;Acc:HGNC:17895] | 6122 | 0.013 | -0.1603 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25820 | 0.000 | -0.6921 | No |
| 4 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31130 | -0.553 | -0.8319 | No |
| 5 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32217 | -0.779 | -0.8562 | No |
| 6 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32921 | -0.962 | -0.8689 | No |
| 7 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8693 | No |
| 8 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34209 | -1.394 | -0.8878 | Yes |
| 9 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.8873 | Yes |
| 10 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 34898 | -1.687 | -0.8854 | Yes |
| 11 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34948 | -1.710 | -0.8757 | Yes |
| 12 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35218 | -1.870 | -0.8708 | Yes |
| 13 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35623 | -2.133 | -0.8679 | Yes |
| 14 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 35625 | -2.133 | -0.8540 | Yes |
| 15 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35629 | -2.136 | -0.8403 | Yes |
| 16 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35715 | -2.202 | -0.8283 | Yes |
| 17 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35996 | -2.449 | -0.8199 | Yes |
| 18 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36021 | -2.474 | -0.8045 | Yes |
| 19 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36023 | -2.475 | -0.7885 | Yes |
| 20 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 36181 | -2.640 | -0.7756 | Yes |
| 21 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.7595 | Yes |
| 22 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36254 | -2.721 | -0.7424 | Yes |
| 23 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36278 | -2.752 | -0.7251 | Yes |
| 24 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36318 | -2.818 | -0.7079 | Yes |
| 25 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.6897 | Yes |
| 26 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36421 | -2.926 | -0.6733 | Yes |
| 27 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 36429 | -2.936 | -0.6544 | Yes |
| 28 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36438 | -2.948 | -0.6355 | Yes |
| 29 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36448 | -2.956 | -0.6165 | Yes |
| 30 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.5975 | Yes |
| 31 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36465 | -2.988 | -0.5782 | Yes |
| 32 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 36487 | -3.032 | -0.5591 | Yes |
| 33 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36495 | -3.045 | -0.5395 | Yes |
| 34 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36533 | -3.091 | -0.5205 | Yes |
| 35 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36549 | -3.110 | -0.5007 | Yes |
| 36 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36578 | -3.169 | -0.4809 | Yes |
| 37 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.4606 | Yes |
| 38 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.4402 | Yes |
| 39 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36652 | -3.287 | -0.4197 | Yes |
| 40 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36684 | -3.340 | -0.3989 | Yes |
| 41 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36693 | -3.364 | -0.3773 | Yes |
| 42 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36735 | -3.416 | -0.3562 | Yes |
| 43 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36771 | -3.483 | -0.3345 | Yes |
| 44 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36778 | -3.498 | -0.3120 | Yes |
| 45 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36802 | -3.541 | -0.2896 | Yes |
| 46 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36809 | -3.551 | -0.2667 | Yes |
| 47 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36819 | -3.570 | -0.2438 | Yes |
| 48 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.2207 | Yes |
| 49 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36856 | -3.657 | -0.1976 | Yes |
| 50 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36868 | -3.678 | -0.1741 | Yes |
| 51 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36871 | -3.689 | -0.1502 | Yes |
| 52 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36886 | -3.735 | -0.1263 | Yes |
| 53 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.1020 | Yes |
| 54 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36957 | -3.986 | -0.0773 | Yes |
| 55 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36988 | -4.101 | -0.0515 | Yes |
| 56 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37012 | -4.172 | -0.0251 | Yes |
| 57 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 37016 | -4.184 | 0.0020 | Yes |
