Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_CENPE |
| Enrichment Score (ES) | -0.892844 |
| Normalized Enrichment Score (NES) | -1.680885 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.1591534E-4 |
| FWER p-Value | 0.002 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2357 | 0.761 | -0.0569 | No |
| 2 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25820 | 0.000 | -0.6901 | No |
| 3 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31130 | -0.553 | -0.8285 | No |
| 4 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32921 | -0.962 | -0.8684 | No |
| 5 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8663 | No |
| 6 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.8677 | No |
| 7 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.8793 | Yes |
| 8 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 34898 | -1.687 | -0.8734 | Yes |
| 9 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35601 | -2.118 | -0.8737 | Yes |
| 10 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35613 | -2.129 | -0.8552 | Yes |
| 11 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 35625 | -2.133 | -0.8366 | Yes |
| 12 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35715 | -2.202 | -0.8195 | Yes |
| 13 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35996 | -2.449 | -0.8054 | Yes |
| 14 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36021 | -2.474 | -0.7842 | Yes |
| 15 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.7661 | Yes |
| 16 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36254 | -2.721 | -0.7426 | Yes |
| 17 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36318 | -2.818 | -0.7194 | Yes |
| 18 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.6946 | Yes |
| 19 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36448 | -2.956 | -0.6718 | Yes |
| 20 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36533 | -3.091 | -0.6467 | Yes |
| 21 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36549 | -3.110 | -0.6196 | Yes |
| 22 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36578 | -3.169 | -0.5924 | Yes |
| 23 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.5646 | Yes |
| 24 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36674 | -3.329 | -0.5372 | Yes |
| 25 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36684 | -3.340 | -0.5080 | Yes |
| 26 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36690 | -3.355 | -0.4784 | Yes |
| 27 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36710 | -3.387 | -0.4490 | Yes |
| 28 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36749 | -3.440 | -0.4196 | Yes |
| 29 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36778 | -3.498 | -0.3895 | Yes |
| 30 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36797 | -3.534 | -0.3587 | Yes |
| 31 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36802 | -3.541 | -0.3275 | Yes |
| 32 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36809 | -3.551 | -0.2963 | Yes |
| 33 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36819 | -3.570 | -0.2650 | Yes |
| 34 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.2335 | Yes |
| 35 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36856 | -3.657 | -0.2018 | Yes |
| 36 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36868 | -3.678 | -0.1696 | Yes |
| 37 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36886 | -3.735 | -0.1370 | Yes |
| 38 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.1037 | Yes |
| 39 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36957 | -3.986 | -0.0697 | Yes |
| 40 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36988 | -4.101 | -0.0343 | Yes |
| 41 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 37016 | -4.184 | 0.0020 | Yes |
