Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_RFC4 |
| Enrichment Score (ES) | -0.8557363 |
| Normalized Enrichment Score (NES) | -1.698446 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RANBP1 | RAN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9847] | 1997 | 0.902 | -0.0468 | No |
| 2 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2357 | 0.761 | -0.0505 | No |
| 3 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 4300 | 0.299 | -0.1006 | No |
| 4 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 4896 | 0.198 | -0.1151 | No |
| 5 | CCT2 | chaperonin containing TCP1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:1615] | 5272 | 0.140 | -0.1241 | No |
| 6 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25820 | 0.000 | -0.6790 | No |
| 7 | SNRPE | small nuclear ribonucleoprotein polypeptide E [Source:HGNC Symbol;Acc:HGNC:11161] | 27388 | -0.043 | -0.7210 | No |
| 8 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 28221 | -0.143 | -0.7423 | No |
| 9 | ITGB3BP | integrin subunit beta 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6157] | 28964 | -0.240 | -0.7604 | No |
| 10 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 29423 | -0.303 | -0.7704 | No |
| 11 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 29558 | -0.319 | -0.7715 | No |
| 12 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 32678 | -0.899 | -0.8486 | Yes |
| 13 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit [Source:HGNC Symbol;Acc:HGNC:11465] | 32865 | -0.942 | -0.8462 | Yes |
| 14 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32921 | -0.962 | -0.8401 | Yes |
| 15 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 32979 | -0.978 | -0.8340 | Yes |
| 16 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8313 | Yes |
| 17 | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 33347 | -1.092 | -0.8270 | Yes |
| 18 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.8252 | Yes |
| 19 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 34033 | -1.321 | -0.8257 | Yes |
| 20 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34209 | -1.394 | -0.8194 | Yes |
| 21 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.8168 | Yes |
| 22 | KNTC1 | kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255] | 34787 | -1.635 | -0.8100 | Yes |
| 23 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35070 | -1.784 | -0.8035 | Yes |
| 24 | H2AZ1 | H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HGNC:4741] | 35155 | -1.829 | -0.7913 | Yes |
| 25 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35218 | -1.870 | -0.7783 | Yes |
| 26 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 35250 | -1.890 | -0.7642 | Yes |
| 27 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35462 | -2.024 | -0.7539 | Yes |
| 28 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35526 | -2.066 | -0.7393 | Yes |
| 29 | CTPS1 | CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] | 35532 | -2.069 | -0.7231 | Yes |
| 30 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35601 | -2.118 | -0.7083 | Yes |
| 31 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35613 | -2.129 | -0.6918 | Yes |
| 32 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35629 | -2.136 | -0.6753 | Yes |
| 33 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35976 | -2.431 | -0.6655 | Yes |
| 34 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35996 | -2.449 | -0.6467 | Yes |
| 35 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36006 | -2.459 | -0.6275 | Yes |
| 36 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36023 | -2.475 | -0.6084 | Yes |
| 37 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36050 | -2.499 | -0.5894 | Yes |
| 38 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36121 | -2.570 | -0.5710 | Yes |
| 39 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36278 | -2.752 | -0.5535 | Yes |
| 40 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.5325 | Yes |
| 41 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36333 | -2.835 | -0.5103 | Yes |
| 42 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.4902 | Yes |
| 43 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36495 | -3.045 | -0.4671 | Yes |
| 44 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36549 | -3.110 | -0.4440 | Yes |
| 45 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.4201 | Yes |
| 46 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36612 | -3.224 | -0.3950 | Yes |
| 47 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.3697 | Yes |
| 48 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36642 | -3.270 | -0.3445 | Yes |
| 49 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.3187 | Yes |
| 50 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36684 | -3.340 | -0.2933 | Yes |
| 51 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36704 | -3.383 | -0.2671 | Yes |
| 52 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36819 | -3.570 | -0.2421 | Yes |
| 53 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.2139 | Yes |
| 54 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36886 | -3.735 | -0.1859 | Yes |
| 55 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36917 | -3.858 | -0.1563 | Yes |
| 56 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36946 | -3.945 | -0.1259 | Yes |
| 57 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36957 | -3.986 | -0.0948 | Yes |
| 58 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36988 | -4.101 | -0.0632 | Yes |
| 59 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37012 | -4.172 | -0.0309 | Yes |
| 60 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 37016 | -4.184 | 0.0020 | Yes |
