Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #KO_LPS_versus_KO_NA.greenbergcls.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | greenbergcls.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_RRM1 |
| Enrichment Score (ES) | -0.8285895 |
| Normalized Enrichment Score (NES) | -1.6942927 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCT6A | chaperonin containing TCP1 subunit 6A [Source:HGNC Symbol;Acc:HGNC:1620] | 1425 | 1.190 | -0.0323 | No |
| 2 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 1529 | 1.129 | -0.0292 | No |
| 3 | PSMD14 | proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889] | 1718 | 1.020 | -0.0289 | No |
| 4 | USP14 | ubiquitin specific peptidase 14 [Source:HGNC Symbol;Acc:HGNC:12612] | 2039 | 0.883 | -0.0329 | No |
| 5 | PTGES3 | prostaglandin E synthase 3 [Source:HGNC Symbol;Acc:HGNC:16049] | 2095 | 0.864 | -0.0299 | No |
| 6 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2357 | 0.761 | -0.0330 | No |
| 7 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 2440 | 0.733 | -0.0314 | No |
| 8 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2463 | 0.725 | -0.0282 | No |
| 9 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 2528 | 0.700 | -0.0262 | No |
| 10 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 4896 | 0.198 | -0.0892 | No |
| 11 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5133 | 0.163 | -0.0947 | No |
| 12 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25820 | 0.000 | -0.6537 | No |
| 13 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 27322 | -0.034 | -0.6941 | No |
| 14 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 27614 | -0.072 | -0.7016 | No |
| 15 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 28221 | -0.143 | -0.7172 | No |
| 16 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 28432 | -0.171 | -0.7220 | No |
| 17 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 28511 | -0.184 | -0.7231 | No |
| 18 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 29558 | -0.319 | -0.7497 | No |
| 19 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 30485 | -0.450 | -0.7724 | No |
| 20 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31130 | -0.553 | -0.7869 | No |
| 21 | CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21906] | 32515 | -0.856 | -0.8199 | No |
| 22 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 32676 | -0.898 | -0.8195 | No |
| 23 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32921 | -0.962 | -0.8210 | No |
| 24 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 32979 | -0.978 | -0.8175 | No |
| 25 | NUP37 | nucleoporin 37 [Source:HGNC Symbol;Acc:HGNC:29929] | 33001 | -0.982 | -0.8129 | No |
| 26 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 33043 | -0.994 | -0.8088 | No |
| 27 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33187 | -1.040 | -0.8072 | No |
| 28 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33629 | -1.186 | -0.8129 | No |
| 29 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34209 | -1.394 | -0.8213 | Yes |
| 30 | FH | fumarate hydratase [Source:HGNC Symbol;Acc:HGNC:3700] | 34337 | -1.448 | -0.8172 | Yes |
| 31 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34560 | -1.537 | -0.8151 | Yes |
| 32 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 34841 | -1.659 | -0.8140 | Yes |
| 33 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34948 | -1.710 | -0.8079 | Yes |
| 34 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35070 | -1.784 | -0.8019 | Yes |
| 35 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35218 | -1.870 | -0.7960 | Yes |
| 36 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 35322 | -1.930 | -0.7887 | Yes |
| 37 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35462 | -2.024 | -0.7819 | Yes |
| 38 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35526 | -2.066 | -0.7728 | Yes |
| 39 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35590 | -2.112 | -0.7635 | Yes |
| 40 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35613 | -2.129 | -0.7529 | Yes |
| 41 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35629 | -2.136 | -0.7421 | Yes |
| 42 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35715 | -2.202 | -0.7329 | Yes |
| 43 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35883 | -2.351 | -0.7251 | Yes |
| 44 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35976 | -2.431 | -0.7149 | Yes |
| 45 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35996 | -2.449 | -0.7026 | Yes |
| 46 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36006 | -2.459 | -0.6900 | Yes |
| 47 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36021 | -2.474 | -0.6774 | Yes |
| 48 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36023 | -2.475 | -0.6645 | Yes |
| 49 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 36043 | -2.495 | -0.6520 | Yes |
| 50 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36050 | -2.499 | -0.6391 | Yes |
| 51 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36232 | -2.692 | -0.6299 | Yes |
| 52 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36254 | -2.721 | -0.6162 | Yes |
| 53 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36278 | -2.752 | -0.6024 | Yes |
| 54 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36318 | -2.818 | -0.5887 | Yes |
| 55 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36325 | -2.825 | -0.5741 | Yes |
| 56 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36333 | -2.835 | -0.5595 | Yes |
| 57 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36438 | -2.948 | -0.5469 | Yes |
| 58 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36448 | -2.956 | -0.5317 | Yes |
| 59 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36458 | -2.975 | -0.5163 | Yes |
| 60 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36495 | -3.045 | -0.5014 | Yes |
| 61 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36506 | -3.053 | -0.4857 | Yes |
| 62 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36533 | -3.091 | -0.4702 | Yes |
| 63 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36549 | -3.110 | -0.4543 | Yes |
| 64 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36578 | -3.169 | -0.4385 | Yes |
| 65 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36597 | -3.196 | -0.4223 | Yes |
| 66 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36612 | -3.224 | -0.4058 | Yes |
| 67 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36619 | -3.233 | -0.3891 | Yes |
| 68 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36622 | -3.236 | -0.3722 | Yes |
| 69 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36647 | -3.278 | -0.3557 | Yes |
| 70 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36652 | -3.287 | -0.3386 | Yes |
| 71 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36684 | -3.340 | -0.3220 | Yes |
| 72 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36690 | -3.355 | -0.3045 | Yes |
| 73 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36710 | -3.387 | -0.2873 | Yes |
| 74 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36735 | -3.416 | -0.2701 | Yes |
| 75 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36797 | -3.534 | -0.2533 | Yes |
| 76 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36802 | -3.541 | -0.2349 | Yes |
| 77 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36819 | -3.570 | -0.2166 | Yes |
| 78 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36831 | -3.600 | -0.1981 | Yes |
| 79 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36856 | -3.657 | -0.1796 | Yes |
| 80 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36868 | -3.678 | -0.1607 | Yes |
| 81 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36886 | -3.735 | -0.1416 | Yes |
| 82 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36911 | -3.844 | -0.1221 | Yes |
| 83 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36915 | -3.854 | -0.1021 | Yes |
| 84 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36946 | -3.945 | -0.0822 | Yes |
| 85 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36957 | -3.986 | -0.0617 | Yes |
| 86 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36988 | -4.101 | -0.0410 | Yes |
| 87 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37012 | -4.172 | -0.0198 | Yes |
| 88 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 37016 | -4.184 | 0.0020 | Yes |
